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Prikaz rezultata 1561-1570 od 1724
Prevention and recovery of CuSO4-induced inhibition of Na+/K+-ATPase and Mg2+-ATPase in rat brain synaptosomes by EDTA
(Toxicology Letters, 1999)
Enzymatic activities of Na+/K+-ATPase and Mg2+-ATPase from rat brain synaptic plasma membrane were studied in the absence and presence of EDTA. The aim of the study was to examine the ability of this strong chelator to ...
The influence of malathion and its decomposition products on free and immobilized acetylcholinesterase
(Russian Journal of Physical Chemistry A, 2008)
The influence of malathion and its four main degradation products found in irradiated solutions (malaoxon, isomalathion, diethyl maleate and O,O-dimethyl phosphate) on acetylcholinesterase (AChE) of free and immobilized ...
The effect of subchronic supplementation with folic acid on homocysteine induced seizures
(Acta Physiologica Hungarica, 2015)
Influence of folic acid on the CNS is still unclear. Folate has a neuroprotective effect, while on the other hand excess folate can exacerbate seizures in epileptics. The aim of the present study was to examine the effect ...
The influence of Al3+ion on porcine pepsin activity in vitro
(Journal of Enzyme Inhibition and Medicinal Chemistry, 2008)
The in vitro effect of Al3+ ions in the concentration range 1.710-6M-8.710-3M on pepsin activity at pH 2, via kinetic parameters and its electrophoretic mobility was evaluated. Kinetic study demonstrated the existence of ...
The effects of omega 3 fatty acid supplementation on brain tissue oxidative status in aged wistar rats
(Hippokratia, 2012)
Background: The omega 3 fatty acids play an important role in many physiological processes. Their effect is well documented in neurodegenerative diseases and inflammatory diseases. Also, aging as a biophysiological process ...
Different Sensitivity of Various Brain Structures to Thioacetamide-Induced Lipid Peroxidation
(Medicinal Chemistry, 2012)
Thioacetamide (TAA) exerts hepatotoxic, neurotoxic and carcinogenic effects. The aim of our study was to investigate the effects of TAA on lipid peroxidation and catalase activity in various rat brain regions. Male Wistar ...
Inhibition of AChE by malathion and some structurally similar compounds
(Journal of Enzyme Inhibition and Medicinal Chemistry, 2008)
Inhibition of bovine erythrocyte acetylcholinesterase (free and immobilized on controlled pore glass) by separate and simultaneous exposure to malathion and malathion transformation products which are generally formed ...
Mechanism of Na+/K+-Atpase and Mg2+-Atpase Inhibition By Metal Ions and Complexes / Mehanizam inhibicije Na+/K+–ATPaze i Mg2+–ATPaze metalnim jonima i kompleksima
(Hemijska industrija, 2009)
The aim of the study was to give an overview of the mechanism of inhibition of Na+/K+-ATPase and Mg2+-ATPase activity, the enzymes playing a key role in the active transport of monovalent cations (Na+ and K+) across the ...
The activity of erythrocyte and brain Na+/K+ and Mg2+-ATPases in rats subjected to acute homocysteine and homocysteine thiolactone administration
(Molecular and Cellular Biochemistry, 2009)
Hyperhomocysteinemia is associated with various pathologies including cardiovascular disease, stroke, and cognitive dysfunctions. Systemic administration of homocysteine can trigger seizures in animals, and patients with ...
Effects of digoxin and gitoxin on the enzymatic activity and kinetic parameters of Na+/K+-ATPase
(Journal of Enzyme Inhibition and Medicinal Chemistry, 2004)
Inhibition of Na+/K+-ATPase activity from human erythrocyte membranes and commercial porcine cerebral cortex by in vitro single and simultaneous exposure to digoxin and gitoxin was investigated to elucidate the difference ...