Enzymatic glucose biosensor based on manganese dioxide nanoparticles decorated on graphene nanoribbons

Abstract

A disposable glucose biosensor was prepared using nanoparticles of MnO2 decorated on graphene nanoribbons by surface modification with drop coating with the GOx and Nafion®. Tested material was synthesized and characterized using several techniques. The biosensor could be operated under physiological conditions (0.1 M phosphate buffer, pH 7.4) and exhibited good reproducibility and stability. The linear range for the amperometric response of the biosensor at operating potential of +0.50 (versus Ag/AgCl) was from 0.1 to 1.4 mmol/l, with a detection limit of 0.05 mmol/l and high sensitivity of 56.32 μA/mmol cm2. Developed method was tested toward glucose quantification in real samples with satisfactory accuracy and precision.