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Copper-enhanced TiO2 nanostructured thin films: Structural, chemical, and antibacterial properties

Authorized Users Only
2025
Authors
Potočnik, Jelena
Latas, Nemanja
Milošević, Milena
Janakiev, Tamara
Stamenković, Tijana
Srejić, Irina
Article (Published version)
Metadata
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Abstract
In this study, titanium was evaporated via e-beam glancing angle deposition in order to obtain nanostructured thin films. Additionally, copper (Cu) nanoparticles (NPs) were electrochemically deposited on top of them. Comprehensive structural analysis showed that the thin film, with a thickness of around 370 nm, consists of slanted columns with an average diameter of 7 nm, while copper nanoparticles range in size from 19 nm to 180 nm. A detailed chemical examination revealed that the deposited thin film contained TiO2, Ti2O3, and TiO phases, where TiO2 is identified as the dominant phase in the sample, while the Cu nanoparticles are composed of metallic Cu and Cu2O. This research intended to evaluate the effect of Cu NPs on the antibacterial activity of TiO2 thin films. Antibacterial tests were carried out on gram-positive Staphylococcus aureus and gram-negative Escherichia coli, Klebsiella aerogenes, and Pseudomonas aeruginosa. The obtained results show that copper nanoparticles improv...e the inhibition of gram-positive bacterial growth.

Keywords:
Titanium dioxide / Copper / Nanostructures / Antibacterial activity
Source:
Applied Surface Science, 2025, 708, 163747-
Funding / projects:
  • Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200017 (University of Belgrade, Institute of Nuclear Sciences 'Vinča', Belgrade-Vinča) (RS-MESTD-inst-2020-200017)
  • Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200178 (University of Belgrade, Faculty of Biology) (RS-MESTD-inst-2020-200178)

DOI: 10.1016/j.apsusc.2025.163747

ISSN: 0169-4332

Scopus: 2-s2.0-105007433642
[ Google Scholar ]
URI
https://vinar.vin.bg.ac.rs/handle/123456789/14945
Collections
  • 040 - Laboratorija za atomsku fiziku
  • Radovi istraživača
Institution/Community
Vinča
TY  - JOUR
AU  - Potočnik, Jelena
AU  - Latas, Nemanja
AU  - Milošević, Milena
AU  - Janakiev, Tamara
AU  - Stamenković, Tijana
AU  - Srejić, Irina
PY  - 2025
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/14945
AB  - In this study, titanium was evaporated via e-beam glancing angle deposition in order to obtain nanostructured thin films. Additionally, copper (Cu) nanoparticles (NPs) were electrochemically deposited on top of them. Comprehensive structural analysis showed that the thin film, with a thickness of around 370 nm, consists of slanted columns with an average diameter of 7 nm, while copper nanoparticles range in size from 19 nm to 180 nm. A detailed chemical examination revealed that the deposited thin film contained TiO2, Ti2O3, and TiO phases, where TiO2 is identified as the dominant phase in the sample, while the Cu nanoparticles are composed of metallic Cu and Cu2O. This research intended to evaluate the effect of Cu NPs on the antibacterial activity of TiO2 thin films. Antibacterial tests were carried out on gram-positive Staphylococcus aureus and gram-negative Escherichia coli, Klebsiella aerogenes, and Pseudomonas aeruginosa. The obtained results show that copper nanoparticles improve the inhibition of gram-positive bacterial growth.
T2  - Applied Surface Science
T1  - Copper-enhanced TiO2 nanostructured thin films: Structural, chemical, and antibacterial properties
VL  - 708
SP  - 163747
DO  - 10.1016/j.apsusc.2025.163747
ER  - 
@article{
author = "Potočnik, Jelena and Latas, Nemanja and Milošević, Milena and Janakiev, Tamara and Stamenković, Tijana and Srejić, Irina",
year = "2025",
abstract = "In this study, titanium was evaporated via e-beam glancing angle deposition in order to obtain nanostructured thin films. Additionally, copper (Cu) nanoparticles (NPs) were electrochemically deposited on top of them. Comprehensive structural analysis showed that the thin film, with a thickness of around 370 nm, consists of slanted columns with an average diameter of 7 nm, while copper nanoparticles range in size from 19 nm to 180 nm. A detailed chemical examination revealed that the deposited thin film contained TiO2, Ti2O3, and TiO phases, where TiO2 is identified as the dominant phase in the sample, while the Cu nanoparticles are composed of metallic Cu and Cu2O. This research intended to evaluate the effect of Cu NPs on the antibacterial activity of TiO2 thin films. Antibacterial tests were carried out on gram-positive Staphylococcus aureus and gram-negative Escherichia coli, Klebsiella aerogenes, and Pseudomonas aeruginosa. The obtained results show that copper nanoparticles improve the inhibition of gram-positive bacterial growth.",
journal = "Applied Surface Science",
title = "Copper-enhanced TiO2 nanostructured thin films: Structural, chemical, and antibacterial properties",
volume = "708",
pages = "163747",
doi = "10.1016/j.apsusc.2025.163747"
}
Potočnik, J., Latas, N., Milošević, M., Janakiev, T., Stamenković, T.,& Srejić, I.. (2025). Copper-enhanced TiO2 nanostructured thin films: Structural, chemical, and antibacterial properties. in Applied Surface Science, 708, 163747.
https://doi.org/10.1016/j.apsusc.2025.163747
Potočnik J, Latas N, Milošević M, Janakiev T, Stamenković T, Srejić I. Copper-enhanced TiO2 nanostructured thin films: Structural, chemical, and antibacterial properties. in Applied Surface Science. 2025;708:163747.
doi:10.1016/j.apsusc.2025.163747 .
Potočnik, Jelena, Latas, Nemanja, Milošević, Milena, Janakiev, Tamara, Stamenković, Tijana, Srejić, Irina, "Copper-enhanced TiO2 nanostructured thin films: Structural, chemical, and antibacterial properties" in Applied Surface Science, 708 (2025):163747,
https://doi.org/10.1016/j.apsusc.2025.163747 . .

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