Cu(II) complexes with meso-HMPAO and d,l-HMPAO were synthesized and characterized using single-crystal X-ray diffraction analysis, FTIR spectroscopy, cyclic voltammetry, and mass spectrometry. The electrochemical data indicated that the complexes bind to DNA molecules, specifically through guanine. These findings suggest that the new compounds have significant potential for further investigation, particularly for their anticancer activity and as models for the development of radiopharmaceuticals with 64Cu.
Source:
PHYSICAL CHEMISTRY 2024 : 17th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings, 2024, 2, 569-572
TY - CONF
AU - Mirković, Marija
AU - Belaj, F.
AU - Perić, Marko
AU - Stanković, D.
AU - Radović, Milan
AU - Milanović, Zorana
AU - Vranješ-Đurić, Sanja
AU - Janković, Drina
AU - Mihajlović-Lalić, Lj.E.
PY - 2024
UR - https://vinar.vin.bg.ac.rs/handle/123456789/14426
AB - Cu(II) complexes with meso-HMPAO and d,l-HMPAO were synthesized and characterized using single-crystal X-ray diffraction analysis, FTIR spectroscopy, cyclic voltammetry, and mass spectrometry. The electrochemical data indicated that the complexes bind to DNA molecules, specifically through guanine. These findings suggest that the new compounds have significant potential for further investigation, particularly for their anticancer activity and as models for the development of radiopharmaceuticals with 64Cu.
PB - Belgrade : Society of Physical Chemists of Serbia
C3 - PHYSICAL CHEMISTRY 2024 : 17th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings
T1 - Development of Cu(II)-MESO-HMPAO complex as a model for potential 64Cu radiopharmaceuticals
VL - 2
SP - 569
EP - 572
DO - 10.46793/Phys.Chem24II.569M
UR - https://hdl.handle.net/21.15107/rcub_vinar_14100
ER -
@conference{
author = "Mirković, Marija and Belaj, F. and Perić, Marko and Stanković, D. and Radović, Milan and Milanović, Zorana and Vranješ-Đurić, Sanja and Janković, Drina and Mihajlović-Lalić, Lj.E.",
year = "2024",
abstract = "Cu(II) complexes with meso-HMPAO and d,l-HMPAO were synthesized and characterized using single-crystal X-ray diffraction analysis, FTIR spectroscopy, cyclic voltammetry, and mass spectrometry. The electrochemical data indicated that the complexes bind to DNA molecules, specifically through guanine. These findings suggest that the new compounds have significant potential for further investigation, particularly for their anticancer activity and as models for the development of radiopharmaceuticals with 64Cu.",
publisher = "Belgrade : Society of Physical Chemists of Serbia",
journal = "PHYSICAL CHEMISTRY 2024 : 17th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings",
title = "Development of Cu(II)-MESO-HMPAO complex as a model for potential 64Cu radiopharmaceuticals",
volume = "2",
pages = "569-572",
doi = "10.46793/Phys.Chem24II.569M",
url = "https://hdl.handle.net/21.15107/rcub_vinar_14100"
}
Mirković, M., Belaj, F., Perić, M., Stanković, D., Radović, M., Milanović, Z., Vranješ-Đurić, S., Janković, D.,& Mihajlović-Lalić, Lj.E.. (2024). Development of Cu(II)-MESO-HMPAO complex as a model for potential 64Cu radiopharmaceuticals. in PHYSICAL CHEMISTRY 2024 : 17th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings
Belgrade : Society of Physical Chemists of Serbia., 2, 569-572.
https://doi.org/10.46793/Phys.Chem24II.569M
https://hdl.handle.net/21.15107/rcub_vinar_14100
Mirković M, Belaj F, Perić M, Stanković D, Radović M, Milanović Z, Vranješ-Đurić S, Janković D, Mihajlović-Lalić L. Development of Cu(II)-MESO-HMPAO complex as a model for potential 64Cu radiopharmaceuticals. in PHYSICAL CHEMISTRY 2024 : 17th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings. 2024;2:569-572.
doi:10.46793/Phys.Chem24II.569M
https://hdl.handle.net/21.15107/rcub_vinar_14100 .
Mirković, Marija, Belaj, F., Perić, Marko, Stanković, D., Radović, Milan, Milanović, Zorana, Vranješ-Đurić, Sanja, Janković, Drina, Mihajlović-Lalić, Lj.E., "Development of Cu(II)-MESO-HMPAO complex as a model for potential 64Cu radiopharmaceuticals" in PHYSICAL CHEMISTRY 2024 : 17th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings, 2 (2024):569-572,
https://doi.org/10.46793/Phys.Chem24II.569M .,
https://hdl.handle.net/21.15107/rcub_vinar_14100 .
