TY  - JOUR
AU  - Romčević, M.
AU  - Kilanski, L.
AU  - Ćurčić, M.
AU  - Paunović, N.
AU  - Prekajski-Đorđević, Marija D.
AU  - Romčević, N.
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/13441
AB  - The interaction between charge carriers and phonons is the primary mechanism through which charge carriers exchange energy with the crystal lattice. A proper understanding of the electron-phonon interaction is of great importance. We conducted a comprehensive investigation to examine the electron-phonon interaction in semiconductor crystals of Zn1-xCdxGeAs2 (0 ≤ x ≤ 1). For this objective, X-ray diffraction, far-infrared reflection, and Raman scattering studies were employed. In addition to the two primary phases, namely ZnGeAs2 and CdGeAs2, four component phases were also identified: ZnAs2, CdAs2, GeAs, and GeAs2. A spatially inhomogeneous distribution of charge carriers was detected, with the highest concentration in the vicinity of the formed GeAs. Analysis of the Far-infrared reflection spectrum of ZnGeAs2 (x = 0) revealed that plasmon-4 phonon interaction occurs, while in CdGeAs2 (x = 1), there is a plasmon-3 phonon interaction. All other samples have both of these interactions, according to their percentage in the composition. Raman measurements revealed that due to the influence of free charge carriers, there is an increase in the intensity of phonon modes, their displacement, or their splitting into two modes. The intensity and the way the electron-phonon interaction vary depending on the local concentration of free carriers, and it is the strongest in the areas around the formed GeAs.  The obtained results and performed analyses revealed the existence of different phases in the material, inhomogeneous charge distribution, and electron-phonon interaction, which are essential properties of thermoelectric materials.
T2  - Physica B: Condensed Matter
T1  - Some aspects of electron-phonon interaction in Zn1-xCdxGeAs2
VL  - 690
SP  - 416264
DO  - 10.1016/j.physb.2024.416264
ER  - 

@article{
author = "Romčević, M. and Kilanski, L. and Ćurčić, M. and Paunović, N. and Prekajski-Đorđević, Marija D. and Romčević, N.",
abstract = "The interaction between charge carriers and phonons is the primary mechanism through which charge carriers exchange energy with the crystal lattice. A proper understanding of the electron-phonon interaction is of great importance. We conducted a comprehensive investigation to examine the electron-phonon interaction in semiconductor crystals of Zn1-xCdxGeAs2 (0 ≤ x ≤ 1). For this objective, X-ray diffraction, far-infrared reflection, and Raman scattering studies were employed. In addition to the two primary phases, namely ZnGeAs2 and CdGeAs2, four component phases were also identified: ZnAs2, CdAs2, GeAs, and GeAs2. A spatially inhomogeneous distribution of charge carriers was detected, with the highest concentration in the vicinity of the formed GeAs. Analysis of the Far-infrared reflection spectrum of ZnGeAs2 (x = 0) revealed that plasmon-4 phonon interaction occurs, while in CdGeAs2 (x = 1), there is a plasmon-3 phonon interaction. All other samples have both of these interactions, according to their percentage in the composition. Raman measurements revealed that due to the influence of free charge carriers, there is an increase in the intensity of phonon modes, their displacement, or their splitting into two modes. The intensity and the way the electron-phonon interaction vary depending on the local concentration of free carriers, and it is the strongest in the areas around the formed GeAs.  The obtained results and performed analyses revealed the existence of different phases in the material, inhomogeneous charge distribution, and electron-phonon interaction, which are essential properties of thermoelectric materials.",
journal = "Physica B: Condensed Matter",
title = "Some aspects of electron-phonon interaction in Zn1-xCdxGeAs2",
volume = "690",
pages = "416264",
doi = "10.1016/j.physb.2024.416264"
}

Romčević, M., Kilanski, L., Ćurčić, M., Paunović, N., Prekajski-Đorđević, M. D.,& Romčević, N..Some aspects of electron-phonon interaction in Zn1-xCdxGeAs2. in Physica B: Condensed Matter, 690, 416264.
https://doi.org/10.1016/j.physb.2024.416264

Romčević M, Kilanski L, Ćurčić M, Paunović N, Prekajski-Đorđević MD, Romčević N. Some aspects of electron-phonon interaction in Zn1-xCdxGeAs2. in Physica B: Condensed Matter.690:416264.
doi:10.1016/j.physb.2024.416264 .

Romčević, M., Kilanski, L., Ćurčić, M., Paunović, N., Prekajski-Đorđević, Marija D., Romčević, N., "Some aspects of electron-phonon interaction in Zn1-xCdxGeAs2" in Physica B: Condensed Matter, 690:416264,
https://doi.org/10.1016/j.physb.2024.416264 . .

TY  - JOUR
AU  - Kočović, David
AU  - Holló, Berta Barta
AU  - Borišev, Ivana
AU  - Leovac, Vukadin
AU  - Vojinović Ješić, Ljiljana
AU  - Giester, Gerald
AU  - Shova, Sergiu
AU  - Tomić, Zoran D.
AU  - Jaćimović, Željko
PY  - 2025
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/13739
AB  - In this paper, the coordination of 4-methylpyrazole (L) to Ni(II) and Zn(II) ions is studied through the reactions of Ni(OAc)2·4H2O and Zn(OAc)2·2H₂O with 4-methylpyrazole in a 1:2 metal-to-ligand molar ratio in ethanol at room temperature. From the reaction mixtures, new complex compounds of formulae: [Ni(OAc)2L4] and [Zn(OAc)2L2] were crystallized. The crystal and molecular structure of the synthesized complexes were determined by single-crystal X-ray structure analysis. The coordination environment of Ni(II) in its complex is octahedral, while that of Zn(II) is tetrahedral. The compounds are characterized by IR spectra and elemental analysis. Their thermal stability, a crucial property, is analyzed by thermogravimetry. To get a better insight into the decomposition mechanism coupled TG-MS measurements were carried out, too. The tests of the antioxidative activity of the new complexes on DPPH radical showed that the Zn(II) complex is more effective than the Ni(II) complex.
T2  - Inorganica Chimica Acta
T1  - Synthesis, characterization and antioxidative capacity of nickel(II) and zinc(II) complexes with 4-methylpyrazole
VL  - 574
SP  - 122363
DO  - 10.1016/j.ica.2024.122363
ER  - 

@article{
author = "Kočović, David and Holló, Berta Barta and Borišev, Ivana and Leovac, Vukadin and Vojinović Ješić, Ljiljana and Giester, Gerald and Shova, Sergiu and Tomić, Zoran D. and Jaćimović, Željko",
year = "2025",
abstract = "In this paper, the coordination of 4-methylpyrazole (L) to Ni(II) and Zn(II) ions is studied through the reactions of Ni(OAc)2·4H2O and Zn(OAc)2·2H₂O with 4-methylpyrazole in a 1:2 metal-to-ligand molar ratio in ethanol at room temperature. From the reaction mixtures, new complex compounds of formulae: [Ni(OAc)2L4] and [Zn(OAc)2L2] were crystallized. The crystal and molecular structure of the synthesized complexes were determined by single-crystal X-ray structure analysis. The coordination environment of Ni(II) in its complex is octahedral, while that of Zn(II) is tetrahedral. The compounds are characterized by IR spectra and elemental analysis. Their thermal stability, a crucial property, is analyzed by thermogravimetry. To get a better insight into the decomposition mechanism coupled TG-MS measurements were carried out, too. The tests of the antioxidative activity of the new complexes on DPPH radical showed that the Zn(II) complex is more effective than the Ni(II) complex.",
journal = "Inorganica Chimica Acta",
title = "Synthesis, characterization and antioxidative capacity of nickel(II) and zinc(II) complexes with 4-methylpyrazole",
volume = "574",
pages = "122363",
doi = "10.1016/j.ica.2024.122363"
}

Kočović, D., Holló, B. B., Borišev, I., Leovac, V., Vojinović Ješić, L., Giester, G., Shova, S., Tomić, Z. D.,& Jaćimović, Ž.. (2025). Synthesis, characterization and antioxidative capacity of nickel(II) and zinc(II) complexes with 4-methylpyrazole. in Inorganica Chimica Acta, 574, 122363.
https://doi.org/10.1016/j.ica.2024.122363

Kočović D, Holló BB, Borišev I, Leovac V, Vojinović Ješić L, Giester G, Shova S, Tomić ZD, Jaćimović Ž. Synthesis, characterization and antioxidative capacity of nickel(II) and zinc(II) complexes with 4-methylpyrazole. in Inorganica Chimica Acta. 2025;574:122363.
doi:10.1016/j.ica.2024.122363 .

Kočović, David, Holló, Berta Barta, Borišev, Ivana, Leovac, Vukadin, Vojinović Ješić, Ljiljana, Giester, Gerald, Shova, Sergiu, Tomić, Zoran D., Jaćimović, Željko, "Synthesis, characterization and antioxidative capacity of nickel(II) and zinc(II) complexes with 4-methylpyrazole" in Inorganica Chimica Acta, 574 (2025):122363,
https://doi.org/10.1016/j.ica.2024.122363 . .

TY  - JOUR
AU  - Mirković, Marija
AU  - Belaj, Ferdinand
AU  - Perić, Marko
AU  - Stanković, Dalibor
AU  - Radović, Magdalena
AU  - Milanović, Zorana
AU  - Vranješ-Đurić, Sanja
AU  - Janković, Drina
AU  - Cvijetić, Ilija
AU  - Mihajlović-Lalić, Ljiljana E.
PY  - 2025
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/13738
AB  - In this work, Cu(II) complexes with meso‑HMPAO and d,l-HMPAO were synthesized. The structural characterisation of the isolated compounds has been done by single-crystal X-ray diffraction analysis, FTIR, and mass spectroscopy. Redox properties of complexes and binding to deoxyribonucleic acid (DNA) molecule have been analysed in detail by cyclic voltammetry and DFT calculations. The results of cyclic voltammetry fully agree with the data obtained by DFT calculations and indicate that the first electron removal takes place from the metal, while the second electron is removed from the ligand. The formation of the complex leads to the shift in oxidation peaks of the ligand from ‒0.29 V to 0,47 V and from 1.18 V to 1,24 V, indicating that ligand in the complex is much more difficult to oxidize. Electrochemical data confirmed the binding between the complex and DNA molecules through guanine. DFT calculations show that the complex is suitable not only for binding purine and pyrimidine bases through a coordination bond but also for additional hydrogen and CH-π interactions of the bases with the ligand. The fluorescence titration experiments revealed a moderate binding affinity of the [Cu-HMPAO]ClO4 complex to human serum albumin (HSA). Molecular docking revealed that this ligand preferentially binds to drug binding site 3 of HSA. Therefore, the novel compounds could be of great interest for further investigation, considering the potential anticancer activity, and as a model for the development of radiopharmaceutical with 64Cu.
T2  - Journal of Molecular Structure
T1  - Synthesis and characterization of Cu(II)‑meso-HMPAO complex as a model for the development of potential 64Cu radiopharmaceutical
VL  - 1321
DO  - 10.1016/j.molstruc.2024.139791
ER  - 

@article{
author = "Mirković, Marija and Belaj, Ferdinand and Perić, Marko and Stanković, Dalibor and Radović, Magdalena and Milanović, Zorana and Vranješ-Đurić, Sanja and Janković, Drina and Cvijetić, Ilija and Mihajlović-Lalić, Ljiljana E.",
year = "2025",
abstract = "In this work, Cu(II) complexes with meso‑HMPAO and d,l-HMPAO were synthesized. The structural characterisation of the isolated compounds has been done by single-crystal X-ray diffraction analysis, FTIR, and mass spectroscopy. Redox properties of complexes and binding to deoxyribonucleic acid (DNA) molecule have been analysed in detail by cyclic voltammetry and DFT calculations. The results of cyclic voltammetry fully agree with the data obtained by DFT calculations and indicate that the first electron removal takes place from the metal, while the second electron is removed from the ligand. The formation of the complex leads to the shift in oxidation peaks of the ligand from ‒0.29 V to 0,47 V and from 1.18 V to 1,24 V, indicating that ligand in the complex is much more difficult to oxidize. Electrochemical data confirmed the binding between the complex and DNA molecules through guanine. DFT calculations show that the complex is suitable not only for binding purine and pyrimidine bases through a coordination bond but also for additional hydrogen and CH-π interactions of the bases with the ligand. The fluorescence titration experiments revealed a moderate binding affinity of the [Cu-HMPAO]ClO4 complex to human serum albumin (HSA). Molecular docking revealed that this ligand preferentially binds to drug binding site 3 of HSA. Therefore, the novel compounds could be of great interest for further investigation, considering the potential anticancer activity, and as a model for the development of radiopharmaceutical with 64Cu.",
journal = "Journal of Molecular Structure",
title = "Synthesis and characterization of Cu(II)‑meso-HMPAO complex as a model for the development of potential 64Cu radiopharmaceutical",
volume = "1321",
doi = "10.1016/j.molstruc.2024.139791"
}

Mirković, M., Belaj, F., Perić, M., Stanković, D., Radović, M., Milanović, Z., Vranješ-Đurić, S., Janković, D., Cvijetić, I.,& Mihajlović-Lalić, L. E.. (2025). Synthesis and characterization of Cu(II)‑meso-HMPAO complex as a model for the development of potential 64Cu radiopharmaceutical. in Journal of Molecular Structure, 1321.
https://doi.org/10.1016/j.molstruc.2024.139791

Mirković M, Belaj F, Perić M, Stanković D, Radović M, Milanović Z, Vranješ-Đurić S, Janković D, Cvijetić I, Mihajlović-Lalić LE. Synthesis and characterization of Cu(II)‑meso-HMPAO complex as a model for the development of potential 64Cu radiopharmaceutical. in Journal of Molecular Structure. 2025;1321.
doi:10.1016/j.molstruc.2024.139791 .

Mirković, Marija, Belaj, Ferdinand, Perić, Marko, Stanković, Dalibor, Radović, Magdalena, Milanović, Zorana, Vranješ-Đurić, Sanja, Janković, Drina, Cvijetić, Ilija, Mihajlović-Lalić, Ljiljana E., "Synthesis and characterization of Cu(II)‑meso-HMPAO complex as a model for the development of potential 64Cu radiopharmaceutical" in Journal of Molecular Structure, 1321 (2025),
https://doi.org/10.1016/j.molstruc.2024.139791 . .

TY  - JOUR
AU  - Cvijović-Alagić, Ivana
AU  - Laketić, Slađana
AU  - Momčilović, Miloš
AU  - Coganović, Jovan
AU  - Veljović, Đorđe
AU  - Bajat, Jelena
AU  - Kojić, Vesna
AU  - Rakin, Marko
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/13747
AB  - The Ti−45Nb (wt.%) alloy properties were investigated in relation to its potential biomedical use. Laser surface modification was utilized to improve its performance in biological systems. As a result of the laser treatment, (Ti,Nb)O scale was formed and various morphological features appeared on the alloy surface. The electrochemical behavior of Ti−45Nb alloy in simulated body conditions was evaluated and showed that the alloy was highly resistant to corrosion deterioration regardless of additional laser surface modification treatment. Nevertheless, the improved corrosion resistance after laser treatment was evident (the corrosion current density of the alloy before laser irradiation was 2.84×10−8 A/cm2, while that after laser treatment with 5 mJ was 0.65×10−8 A/cm2) and ascribed to the rapid formation of a complex and passivating bi-modal surface oxide layer. Alloy cytotoxicity and effects of the Ti−45Nb alloy laser surface modification on the MRC-5 cell viability, morphology, and proliferation were also investigated. The Ti−45Nb alloy showed no cytotoxic effect. Moreover, cells showed improved viability and adherence to the alloy surface after the laser irradiation treatment. The highest average cell viability of 115.37% was attained for the alloy laser-irradiated with 15 mJ. Results showed that the laser surface modification can be successfully utilized to significantly improve alloy performance in a biological environment.
T2  - Transactions of Nonferrous Metals Society of China
T1  - Laser processing effects on Ti−45Nb alloy surface, corrosive and biocompatible properties
VL  - 34
IS  - 8
SP  - 2533
EP  - 2551
DO  - 10.1016/S1003-6326(24)66558-1
ER  - 

@article{
author = "Cvijović-Alagić, Ivana and Laketić, Slađana and Momčilović, Miloš and Coganović, Jovan and Veljović, Đorđe and Bajat, Jelena and Kojić, Vesna and Rakin, Marko",
year = "2024",
abstract = "The Ti−45Nb (wt.%) alloy properties were investigated in relation to its potential biomedical use. Laser surface modification was utilized to improve its performance in biological systems. As a result of the laser treatment, (Ti,Nb)O scale was formed and various morphological features appeared on the alloy surface. The electrochemical behavior of Ti−45Nb alloy in simulated body conditions was evaluated and showed that the alloy was highly resistant to corrosion deterioration regardless of additional laser surface modification treatment. Nevertheless, the improved corrosion resistance after laser treatment was evident (the corrosion current density of the alloy before laser irradiation was 2.84×10−8 A/cm2, while that after laser treatment with 5 mJ was 0.65×10−8 A/cm2) and ascribed to the rapid formation of a complex and passivating bi-modal surface oxide layer. Alloy cytotoxicity and effects of the Ti−45Nb alloy laser surface modification on the MRC-5 cell viability, morphology, and proliferation were also investigated. The Ti−45Nb alloy showed no cytotoxic effect. Moreover, cells showed improved viability and adherence to the alloy surface after the laser irradiation treatment. The highest average cell viability of 115.37% was attained for the alloy laser-irradiated with 15 mJ. Results showed that the laser surface modification can be successfully utilized to significantly improve alloy performance in a biological environment.",
journal = "Transactions of Nonferrous Metals Society of China",
title = "Laser processing effects on Ti−45Nb alloy surface, corrosive and biocompatible properties",
volume = "34",
number = "8",
pages = "2533-2551",
doi = "10.1016/S1003-6326(24)66558-1"
}

Cvijović-Alagić, I., Laketić, S., Momčilović, M., Coganović, J., Veljović, Đ., Bajat, J., Kojić, V.,& Rakin, M.. (2024). Laser processing effects on Ti−45Nb alloy surface, corrosive and biocompatible properties. in Transactions of Nonferrous Metals Society of China, 34(8), 2533-2551.
https://doi.org/10.1016/S1003-6326(24)66558-1

Cvijović-Alagić I, Laketić S, Momčilović M, Coganović J, Veljović Đ, Bajat J, Kojić V, Rakin M. Laser processing effects on Ti−45Nb alloy surface, corrosive and biocompatible properties. in Transactions of Nonferrous Metals Society of China. 2024;34(8):2533-2551.
doi:10.1016/S1003-6326(24)66558-1 .

Cvijović-Alagić, Ivana, Laketić, Slađana, Momčilović, Miloš, Coganović, Jovan, Veljović, Đorđe, Bajat, Jelena, Kojić, Vesna, Rakin, Marko, "Laser processing effects on Ti−45Nb alloy surface, corrosive and biocompatible properties" in Transactions of Nonferrous Metals Society of China, 34, no. 8 (2024):2533-2551,
https://doi.org/10.1016/S1003-6326(24)66558-1 . .

TY  - JOUR
AU  - Milovanović, Dubravka
AU  - Rajčić, Boris
AU  - Ranković, Dragan
AU  - Stankov, Biljana
AU  - Čekada, Miha
AU  - Ciganović, Jovan
AU  - Đurđević-Milošević, Dragica
AU  - Stević, Zoran
AU  - Kuzmanović, Miroslav
AU  - Šibalija, Tatjana
AU  - Petronić, Sanja
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12723
AB  - This paper presents a study and comparison of surface effects induced by picosecond and nanosecond laser modification of a Ti6Al4V alloy surface under different ambient conditions: air and argon- and nitrogen-rich atmospheres. Detailed surface characterization was performed for all experimental conditions. Damage threshold fluences for picosecond and nanosecond laser irradiation in all three ambient conditions were determined. The observed surface features were a resolidified pool of molten material, craters, hydrodynamic effects and parallel periodic surface structures. Laser-induced periodic surface structures are formed by multi-mode-beam nanosecond laser action and picosecond laser action. Crown-like structures at crater rims are specific features for picosecond Nd:YAG laser action in argon-rich ambient conditions. Elemental analysis of the surfaces indicated nitride compound formation only in the nitrogen-rich ambient conditions. The constituents of the formed plasma were also investigated. Exploring the impact of process control parameters on output responses has been undertaken within the context of laser modification under different environmental conditions. Parametric optimization of the nanosecond laser modification was carried out by implementing an advanced method based on Taguchi’s parametric design and multivariate statistical techniques, and optimal settings are proposed for each atmosphere.
T2  - Micromachines
T1  - Microstructure Formations Resulting from Nanosecond and Picosecond Laser Irradiation of a Ti-Based Alloy under Controlled Atmospheric Conditions and Optimization of the Irradiation Process
VL  - 15
IS  - 1
SP  - 5
DO  - 10.3390/mi15010005
ER  - 

@article{
author = "Milovanović, Dubravka and Rajčić, Boris and Ranković, Dragan and Stankov, Biljana and Čekada, Miha and Ciganović, Jovan and Đurđević-Milošević, Dragica and Stević, Zoran and Kuzmanović, Miroslav and Šibalija, Tatjana and Petronić, Sanja",
year = "2024",
abstract = "This paper presents a study and comparison of surface effects induced by picosecond and nanosecond laser modification of a Ti6Al4V alloy surface under different ambient conditions: air and argon- and nitrogen-rich atmospheres. Detailed surface characterization was performed for all experimental conditions. Damage threshold fluences for picosecond and nanosecond laser irradiation in all three ambient conditions were determined. The observed surface features were a resolidified pool of molten material, craters, hydrodynamic effects and parallel periodic surface structures. Laser-induced periodic surface structures are formed by multi-mode-beam nanosecond laser action and picosecond laser action. Crown-like structures at crater rims are specific features for picosecond Nd:YAG laser action in argon-rich ambient conditions. Elemental analysis of the surfaces indicated nitride compound formation only in the nitrogen-rich ambient conditions. The constituents of the formed plasma were also investigated. Exploring the impact of process control parameters on output responses has been undertaken within the context of laser modification under different environmental conditions. Parametric optimization of the nanosecond laser modification was carried out by implementing an advanced method based on Taguchi’s parametric design and multivariate statistical techniques, and optimal settings are proposed for each atmosphere.",
journal = "Micromachines",
title = "Microstructure Formations Resulting from Nanosecond and Picosecond Laser Irradiation of a Ti-Based Alloy under Controlled Atmospheric Conditions and Optimization of the Irradiation Process",
volume = "15",
number = "1",
pages = "5",
doi = "10.3390/mi15010005"
}

Milovanović, D., Rajčić, B., Ranković, D., Stankov, B., Čekada, M., Ciganović, J., Đurđević-Milošević, D., Stević, Z., Kuzmanović, M., Šibalija, T.,& Petronić, S.. (2024). Microstructure Formations Resulting from Nanosecond and Picosecond Laser Irradiation of a Ti-Based Alloy under Controlled Atmospheric Conditions and Optimization of the Irradiation Process. in Micromachines, 15(1), 5.
https://doi.org/10.3390/mi15010005

Milovanović D, Rajčić B, Ranković D, Stankov B, Čekada M, Ciganović J, Đurđević-Milošević D, Stević Z, Kuzmanović M, Šibalija T, Petronić S. Microstructure Formations Resulting from Nanosecond and Picosecond Laser Irradiation of a Ti-Based Alloy under Controlled Atmospheric Conditions and Optimization of the Irradiation Process. in Micromachines. 2024;15(1):5.
doi:10.3390/mi15010005 .

Milovanović, Dubravka, Rajčić, Boris, Ranković, Dragan, Stankov, Biljana, Čekada, Miha, Ciganović, Jovan, Đurđević-Milošević, Dragica, Stević, Zoran, Kuzmanović, Miroslav, Šibalija, Tatjana, Petronić, Sanja, "Microstructure Formations Resulting from Nanosecond and Picosecond Laser Irradiation of a Ti-Based Alloy under Controlled Atmospheric Conditions and Optimization of the Irradiation Process" in Micromachines, 15, no. 1 (2024):5,
https://doi.org/10.3390/mi15010005 . .

TY  - JOUR
AU  - Cvijović-Alagić, Ivana
AU  - Laketić, Slađana
AU  - Momčilović, Miloš
AU  - Ciganović, Jovan
AU  - Bajat, Jelena
AU  - Kojić, Vesna
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/13227
AB  - The Ti-45Nb (mass%) alloy’s corrosive and biocompatible response in simulated physiological conditions was investigated before and after its additional high-pressure torsion (HPT) and laser irradiation processing. The grain size reduction from 2.76 μm to ~ 200 nm and the appearance of laser-induced morphologically altered and highly oxidized surface led to the significant improvement of alloy corrosion resistance and cell–implant interaction. Moreover, an additional increase of the laser pulse energy from 5 to 15 mJ during the alloy irradiation in the air led to an increase in the surface oxygen content from 13.64 to 23.89% accompanied by an increase of excellent cell viability from 127.18 to 134.42%. As a result of the controlled alloy microstructural and surface modifications, the formation of protective bi-modal mixed Ti- and Nb-oxide external scale was enabled. The presence of this surface oxide scale enhanced the alloy’s resistance to corrosion deterioration and simultaneously boosted cell viability and proliferation.
T2  - Acta Metallurgica Sinica (English Letters)
T1  - Impact of Microstructural and Surface Modifications on the Ti-45Nb Alloy’s Response to Bio-Environment
DO  - 10.1007/s40195-024-01705-0
ER  - 

@article{
author = "Cvijović-Alagić, Ivana and Laketić, Slađana and Momčilović, Miloš and Ciganović, Jovan and Bajat, Jelena and Kojić, Vesna",
year = "2024",
abstract = "The Ti-45Nb (mass%) alloy’s corrosive and biocompatible response in simulated physiological conditions was investigated before and after its additional high-pressure torsion (HPT) and laser irradiation processing. The grain size reduction from 2.76 μm to ~ 200 nm and the appearance of laser-induced morphologically altered and highly oxidized surface led to the significant improvement of alloy corrosion resistance and cell–implant interaction. Moreover, an additional increase of the laser pulse energy from 5 to 15 mJ during the alloy irradiation in the air led to an increase in the surface oxygen content from 13.64 to 23.89% accompanied by an increase of excellent cell viability from 127.18 to 134.42%. As a result of the controlled alloy microstructural and surface modifications, the formation of protective bi-modal mixed Ti- and Nb-oxide external scale was enabled. The presence of this surface oxide scale enhanced the alloy’s resistance to corrosion deterioration and simultaneously boosted cell viability and proliferation.",
journal = "Acta Metallurgica Sinica (English Letters)",
title = "Impact of Microstructural and Surface Modifications on the Ti-45Nb Alloy’s Response to Bio-Environment",
doi = "10.1007/s40195-024-01705-0"
}

Cvijović-Alagić, I., Laketić, S., Momčilović, M., Ciganović, J., Bajat, J.,& Kojić, V.. (2024). Impact of Microstructural and Surface Modifications on the Ti-45Nb Alloy’s Response to Bio-Environment. in Acta Metallurgica Sinica (English Letters).
https://doi.org/10.1007/s40195-024-01705-0

Cvijović-Alagić I, Laketić S, Momčilović M, Ciganović J, Bajat J, Kojić V. Impact of Microstructural and Surface Modifications on the Ti-45Nb Alloy’s Response to Bio-Environment. in Acta Metallurgica Sinica (English Letters). 2024;.
doi:10.1007/s40195-024-01705-0 .

Cvijović-Alagić, Ivana, Laketić, Slađana, Momčilović, Miloš, Ciganović, Jovan, Bajat, Jelena, Kojić, Vesna, "Impact of Microstructural and Surface Modifications on the Ti-45Nb Alloy’s Response to Bio-Environment" in Acta Metallurgica Sinica (English Letters) (2024),
https://doi.org/10.1007/s40195-024-01705-0 . .

TY  - JOUR
AU  - Zagorac, Dejan
AU  - Prasad, Dasari
AU  - Škundrić, Tamara
AU  - Yadav, Kedar
AU  - Singh, Surender
AU  - Laketić, Slađana
AU  - Zagorac, Jelena
AU  - Momčilović, Miloš
AU  - Cvijović-Alagić, Ivana
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/13300
AB  - Mechanical properties and structure-property relationship of the Ti-45Nb (mass%) alloy with potential applications in biomedicine were investigated using a multidisciplinary approach. Because the biomechanical compatibility of metallic implant materials can be significantly improved by microstructural refinement and laser surface modification (LSM), the present study concentrates on the investigation of the mechanical properties of the Ti-45Nb alloy subjected to extreme processing conditions to evaluate their impact on the alloy improved applicability in the bio-environment. The alloy was therefore subjected to high-pressure torsion (HPT) and LSM processing to obtain favorable alloy characteristics. Crystal structure prediction was conducted using data mining (DM) and evolutionary algorithms (EA). All the obtained potential structure candidates were submitted to the local optimizations at the level of density functional theory (DFT); subsequently, the phonon lattice dynamics and mechanical properties were systematically investigated. The alloy structure progression and mechanical characteristics were examined under the influence of extremely high temperatures induced during the LSM processing and the extreme pressure achieved during the HPT treatment. XRD characterization was performed using experimental and theoretical methods showing the presence of bcc β-Ti and orthorhombic Cmcm Ti4Nb phase. Mechanical properties such as Young's modulus, Vicker's hardness, and plasticity of the most relevant Ti4Nb modifications predicted after DM-EA-DFT were found to corroborate well with the experimental results of nanoindentation measurements. The present study reveals that the additional processing of the Ti-45Nb alloy under extreme conditions leads to significant improvement in the alloy's bio-mechanical compatibility.
T2  - CrystEngComm
T1  - Mechanical properties and behavior of the Ti–45Nb alloy subjected to extreme conditions
VL  - 26
IS  - 22
SP  - 2989
EP  - 3004
DO  - 10.1039/D4CE00076E
ER  - 

@article{
author = "Zagorac, Dejan and Prasad, Dasari and Škundrić, Tamara and Yadav, Kedar and Singh, Surender and Laketić, Slađana and Zagorac, Jelena and Momčilović, Miloš and Cvijović-Alagić, Ivana",
year = "2024",
abstract = "Mechanical properties and structure-property relationship of the Ti-45Nb (mass%) alloy with potential applications in biomedicine were investigated using a multidisciplinary approach. Because the biomechanical compatibility of metallic implant materials can be significantly improved by microstructural refinement and laser surface modification (LSM), the present study concentrates on the investigation of the mechanical properties of the Ti-45Nb alloy subjected to extreme processing conditions to evaluate their impact on the alloy improved applicability in the bio-environment. The alloy was therefore subjected to high-pressure torsion (HPT) and LSM processing to obtain favorable alloy characteristics. Crystal structure prediction was conducted using data mining (DM) and evolutionary algorithms (EA). All the obtained potential structure candidates were submitted to the local optimizations at the level of density functional theory (DFT); subsequently, the phonon lattice dynamics and mechanical properties were systematically investigated. The alloy structure progression and mechanical characteristics were examined under the influence of extremely high temperatures induced during the LSM processing and the extreme pressure achieved during the HPT treatment. XRD characterization was performed using experimental and theoretical methods showing the presence of bcc β-Ti and orthorhombic Cmcm Ti4Nb phase. Mechanical properties such as Young's modulus, Vicker's hardness, and plasticity of the most relevant Ti4Nb modifications predicted after DM-EA-DFT were found to corroborate well with the experimental results of nanoindentation measurements. The present study reveals that the additional processing of the Ti-45Nb alloy under extreme conditions leads to significant improvement in the alloy's bio-mechanical compatibility.",
journal = "CrystEngComm",
title = "Mechanical properties and behavior of the Ti–45Nb alloy subjected to extreme conditions",
volume = "26",
number = "22",
pages = "2989-3004",
doi = "10.1039/D4CE00076E"
}

Zagorac, D., Prasad, D., Škundrić, T., Yadav, K., Singh, S., Laketić, S., Zagorac, J., Momčilović, M.,& Cvijović-Alagić, I.. (2024). Mechanical properties and behavior of the Ti–45Nb alloy subjected to extreme conditions. in CrystEngComm, 26(22), 2989-3004.
https://doi.org/10.1039/D4CE00076E

Zagorac D, Prasad D, Škundrić T, Yadav K, Singh S, Laketić S, Zagorac J, Momčilović M, Cvijović-Alagić I. Mechanical properties and behavior of the Ti–45Nb alloy subjected to extreme conditions. in CrystEngComm. 2024;26(22):2989-3004.
doi:10.1039/D4CE00076E .

Zagorac, Dejan, Prasad, Dasari, Škundrić, Tamara, Yadav, Kedar, Singh, Surender, Laketić, Slađana, Zagorac, Jelena, Momčilović, Miloš, Cvijović-Alagić, Ivana, "Mechanical properties and behavior of the Ti–45Nb alloy subjected to extreme conditions" in CrystEngComm, 26, no. 22 (2024):2989-3004,
https://doi.org/10.1039/D4CE00076E . .

TY  - JOUR
AU  - Gavrilović, Tamara
AU  - Ćirić, Aleksandar
AU  - Medić, Mina M.
AU  - Ristić, Zoran
AU  - Periša, Jovana
AU  - Antić, Željka
AU  - Dramićanin, Miroslav
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/13710
AB  - first_pagesettingsOrder Article Reprints Open AccessArticle Structure–Dopant Concentration Relations in Europium-Doped Yttrium Molybdate and Peak-Sharpening for Luminescence Temperature Sensing by Tamara Gavrilović *,Aleksandar Ćirić *,Mina Medić,Zoran RistićORCID,Jovana Periša,Željka AntićORCID andMiroslav D. Dramićanin Center of Excellence for Photoconversion, Vinča Institute of Nuclear Sciences-National Institute of the Republic of Serbia, University of Belgrade, 11001 Belgrade, Serbia * Authors to whom correspondence should be addressed. Materials 2024, 17(17), 4267; https://doi.org/10.3390/ma17174267 Submission received: 23 July 2024 / Revised: 12 August 2024 / Accepted: 20 August 2024 / Published: 28 August 2024 (This article belongs to the Special Issue Exploring the Versatility of Piezoelectric and Dielectric Electroceramics: Synthesis, Characterization, and Applications) Downloadkeyboard_arrow_down Browse Figures Versions Notes Abstract A set of Eu3+-doped molybdates, Y2−xEuxMo3O12 (x = 0.04; 0.16; 0.2; 0.4; 0.8; 1; 1.6; 2), was synthesized using a solid-state technique and their properties studied as a function of Eu3+ concentration. X-ray diffraction showed that the replacement of Y3+ with larger Eu3+ resulted in a transformation from orthorhombic (low doping concentrations) through tetragonal (high doping concentrations), reaching monoclinic structure for full replacement in Eu2Mo3O12. The intensity of typical Eu3+ red emission slightly increases in the orthorhombic structure then rises significantly with dopant concentration and has the highest value for the tetragonal Y2Mo3O12:80mol% Eu3+. Further, the complete substitution of Y3+ with Eu3+ in the case of monoclinic Eu2Mo3O12 leads to decreased emission intensity. Lifetime follows a similar trend; it is lower in the orthorhombic structure, reaching slightly higher values for the tetragonal structure and showing a strong decrease for monoclinic Eu2Mo3O12. Temperature-sensing properties of the sample with the highest red Eu3+ emission, Y2Mo3O12:80mol% Eu3+, were analyzed by the luminescence intensity ratio method. For the first time, the peak-sharpening algorithm was employed to separate overlapping peaks in luminescence thermometry, in contrast to the peak deconvolution method. The Sr (relative sensitivity) value of 2.8 % K−1 was obtained at room temperature.
T2  - Materials
T1  - Structure–Dopant Concentration Relations in Europium-Doped Yttrium Molybdate and Peak-Sharpening for Luminescence Temperature Sensing
VL  - 17
IS  - 17
SP  - 4267
DO  - 10.3390/ma17174267
ER  - 

@article{
author = "Gavrilović, Tamara and Ćirić, Aleksandar and Medić, Mina M. and Ristić, Zoran and Periša, Jovana and Antić, Željka and Dramićanin, Miroslav",
year = "2024",
abstract = "first_pagesettingsOrder Article Reprints Open AccessArticle Structure–Dopant Concentration Relations in Europium-Doped Yttrium Molybdate and Peak-Sharpening for Luminescence Temperature Sensing by Tamara Gavrilović *,Aleksandar Ćirić *,Mina Medić,Zoran RistićORCID,Jovana Periša,Željka AntićORCID andMiroslav D. Dramićanin Center of Excellence for Photoconversion, Vinča Institute of Nuclear Sciences-National Institute of the Republic of Serbia, University of Belgrade, 11001 Belgrade, Serbia * Authors to whom correspondence should be addressed. Materials 2024, 17(17), 4267; https://doi.org/10.3390/ma17174267 Submission received: 23 July 2024 / Revised: 12 August 2024 / Accepted: 20 August 2024 / Published: 28 August 2024 (This article belongs to the Special Issue Exploring the Versatility of Piezoelectric and Dielectric Electroceramics: Synthesis, Characterization, and Applications) Downloadkeyboard_arrow_down Browse Figures Versions Notes Abstract A set of Eu3+-doped molybdates, Y2−xEuxMo3O12 (x = 0.04; 0.16; 0.2; 0.4; 0.8; 1; 1.6; 2), was synthesized using a solid-state technique and their properties studied as a function of Eu3+ concentration. X-ray diffraction showed that the replacement of Y3+ with larger Eu3+ resulted in a transformation from orthorhombic (low doping concentrations) through tetragonal (high doping concentrations), reaching monoclinic structure for full replacement in Eu2Mo3O12. The intensity of typical Eu3+ red emission slightly increases in the orthorhombic structure then rises significantly with dopant concentration and has the highest value for the tetragonal Y2Mo3O12:80mol% Eu3+. Further, the complete substitution of Y3+ with Eu3+ in the case of monoclinic Eu2Mo3O12 leads to decreased emission intensity. Lifetime follows a similar trend; it is lower in the orthorhombic structure, reaching slightly higher values for the tetragonal structure and showing a strong decrease for monoclinic Eu2Mo3O12. Temperature-sensing properties of the sample with the highest red Eu3+ emission, Y2Mo3O12:80mol% Eu3+, were analyzed by the luminescence intensity ratio method. For the first time, the peak-sharpening algorithm was employed to separate overlapping peaks in luminescence thermometry, in contrast to the peak deconvolution method. The Sr (relative sensitivity) value of 2.8 % K−1 was obtained at room temperature.",
journal = "Materials",
title = "Structure–Dopant Concentration Relations in Europium-Doped Yttrium Molybdate and Peak-Sharpening for Luminescence Temperature Sensing",
volume = "17",
number = "17",
pages = "4267",
doi = "10.3390/ma17174267"
}

Gavrilović, T., Ćirić, A., Medić, M. M., Ristić, Z., Periša, J., Antić, Ž.,& Dramićanin, M.. (2024). Structure–Dopant Concentration Relations in Europium-Doped Yttrium Molybdate and Peak-Sharpening for Luminescence Temperature Sensing. in Materials, 17(17), 4267.
https://doi.org/10.3390/ma17174267

Gavrilović T, Ćirić A, Medić MM, Ristić Z, Periša J, Antić Ž, Dramićanin M. Structure–Dopant Concentration Relations in Europium-Doped Yttrium Molybdate and Peak-Sharpening for Luminescence Temperature Sensing. in Materials. 2024;17(17):4267.
doi:10.3390/ma17174267 .

Gavrilović, Tamara, Ćirić, Aleksandar, Medić, Mina M., Ristić, Zoran, Periša, Jovana, Antić, Željka, Dramićanin, Miroslav, "Structure–Dopant Concentration Relations in Europium-Doped Yttrium Molybdate and Peak-Sharpening for Luminescence Temperature Sensing" in Materials, 17, no. 17 (2024):4267,
https://doi.org/10.3390/ma17174267 . .

TY  - JOUR
AU  - Radenković, Marina
AU  - Petrović, Jelena
AU  - Pap, Sabolc
AU  - Kalijadis, Ana
AU  - Momčilović, Miloš
AU  - Krstulović, Nikša
AU  - Živković, Sanja
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12206
AB  - Toxic elements, lead, and copper are often found in wastewater discharged from industries such as mining. The discharge of untreated effluent poses severe environmental challenges and sorption methods using agricultural waste materials are proposed as an efficient and cost-effective solution. For this research, activated sunflower material (ASM) was prepared from abundantly available agricultural sunflower waste residues and utilised to remove Pb2+ and Cu2+ ions from an aqueous medium. To begin, we examine variables that may have an impact on the adsorption process, such as pH, contact time, adsorbent dose, and initial concentration using Box-Behnken Design (BBD) to find optimal conditions. Maximum removal efficiency was found at a pH of 5, contact time of 180 min, and initial concentration of 50 mg/L for Pb2+ and 150 mg/L for Cu2+. Additionally, adsorbent dose differed by element, for Cu2+ it was 200 mg, whilst for Pb2+ it was 124 mg. Features of activated carbon such as morphology, elemental composition, textural properties, and surface functionalities were characterised using SEM-EDS, BET, FTIR, and XPS. The adsorption equilibrium data were analysed by Langmuir, Freundlich, and Dubinin-Radushkevich isotherm models. It was found that the obtained results for Pb2+ adsorption were better described with the Freundlich isotherm model. Maximum adsorption capacities for Pb2+ and Cu2+ were 91.8 mg/g and 20.5 mg/g, respectively. Furthermore, kinetic studies confirmed that the adsorption process followed a pseudo-first-order kinetic model for Pb2+, but for Cu2+ all applied kinetic models fitted experimental data with the same values of the correlation coefficient (R2 = 0.99). After comprehensive analysis using the methods mentioned above, ASM was tested for the removal of Cu2+ from mining wastewater sample, and the obtained removal efficiency was 98.6% ± 2.0%. The results of desorption experiments conducted, confirm that ASM has good potential to be reused for the purpose of removing Cu2+ from wastewater.
T2  - Chemosphere
T1  - Waste biomass derived highly-porous carbon material for toxic metal removal: Optimisation, mechanisms and environmental implications
VL  - 347
SP  - 140684
DO  - 10.1016/j.chemosphere.2023.140684
ER  - 

@article{
author = "Radenković, Marina and Petrović, Jelena and Pap, Sabolc and Kalijadis, Ana and Momčilović, Miloš and Krstulović, Nikša and Živković, Sanja",
year = "2024",
abstract = "Toxic elements, lead, and copper are often found in wastewater discharged from industries such as mining. The discharge of untreated effluent poses severe environmental challenges and sorption methods using agricultural waste materials are proposed as an efficient and cost-effective solution. For this research, activated sunflower material (ASM) was prepared from abundantly available agricultural sunflower waste residues and utilised to remove Pb2+ and Cu2+ ions from an aqueous medium. To begin, we examine variables that may have an impact on the adsorption process, such as pH, contact time, adsorbent dose, and initial concentration using Box-Behnken Design (BBD) to find optimal conditions. Maximum removal efficiency was found at a pH of 5, contact time of 180 min, and initial concentration of 50 mg/L for Pb2+ and 150 mg/L for Cu2+. Additionally, adsorbent dose differed by element, for Cu2+ it was 200 mg, whilst for Pb2+ it was 124 mg. Features of activated carbon such as morphology, elemental composition, textural properties, and surface functionalities were characterised using SEM-EDS, BET, FTIR, and XPS. The adsorption equilibrium data were analysed by Langmuir, Freundlich, and Dubinin-Radushkevich isotherm models. It was found that the obtained results for Pb2+ adsorption were better described with the Freundlich isotherm model. Maximum adsorption capacities for Pb2+ and Cu2+ were 91.8 mg/g and 20.5 mg/g, respectively. Furthermore, kinetic studies confirmed that the adsorption process followed a pseudo-first-order kinetic model for Pb2+, but for Cu2+ all applied kinetic models fitted experimental data with the same values of the correlation coefficient (R2 = 0.99). After comprehensive analysis using the methods mentioned above, ASM was tested for the removal of Cu2+ from mining wastewater sample, and the obtained removal efficiency was 98.6% ± 2.0%. The results of desorption experiments conducted, confirm that ASM has good potential to be reused for the purpose of removing Cu2+ from wastewater.",
journal = "Chemosphere",
title = "Waste biomass derived highly-porous carbon material for toxic metal removal: Optimisation, mechanisms and environmental implications",
volume = "347",
pages = "140684",
doi = "10.1016/j.chemosphere.2023.140684"
}

Radenković, M., Petrović, J., Pap, S., Kalijadis, A., Momčilović, M., Krstulović, N.,& Živković, S.. (2024). Waste biomass derived highly-porous carbon material for toxic metal removal: Optimisation, mechanisms and environmental implications. in Chemosphere, 347, 140684.
https://doi.org/10.1016/j.chemosphere.2023.140684

Radenković M, Petrović J, Pap S, Kalijadis A, Momčilović M, Krstulović N, Živković S. Waste biomass derived highly-porous carbon material for toxic metal removal: Optimisation, mechanisms and environmental implications. in Chemosphere. 2024;347:140684.
doi:10.1016/j.chemosphere.2023.140684 .

Radenković, Marina, Petrović, Jelena, Pap, Sabolc, Kalijadis, Ana, Momčilović, Miloš, Krstulović, Nikša, Živković, Sanja, "Waste biomass derived highly-porous carbon material for toxic metal removal: Optimisation, mechanisms and environmental implications" in Chemosphere, 347 (2024):140684,
https://doi.org/10.1016/j.chemosphere.2023.140684 . .

TY  - JOUR
AU  - Jovanović Macura, Irena
AU  - Đuričić, Ivana
AU  - Major, Tamara
AU  - Milanović, Desanka
AU  - Šobajić, Slađana
AU  - Kanazir, Selma
AU  - Ivković, Sanja
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12541
AB  - Introduction: During fetal development, the proper development of neural and visual systems relies on the maternal supplementation of omega-3 fatty acids through placental transfer. Pregnant women are strongly advised to augment their diet with additional sources of omega-3, such as fish oil (FO). This supplementation has been linked to a reduced risk of preterm birth, pre-eclampsia, and perinatal depression. Recently, higher doses of omega-3 supplementation have been recommended for pregnant women. Considering that omega-3 fatty acids, particularly docosahexaenoic acid (DHA), play a crucial role in maintaining the delicate homeostasis required for the proper functioning of the retina and photoreceptors the effects of high-dose fish oil (FO) supplementation during pregnancy and lactation on the retina and retinal pigmented epithelium (RPE) in healthy offspring warrant better understanding.  Methods: The fatty acid content and the changes in the expression of the genes regulating cholesterol homeostasis and DHA transport in the retina and RPE were evaluated following the high-dose FO supplementation.  Results: Our study demonstrated that despite the high-dose FO treatment during pregnancy and lactation, the rigorous DHA homeostasis in the retina and RPE of the two-month-old offspring remained balanced. Another significant finding of this study is the increase in the expression levels of major facilitator superfamily domain-containing protein (Mfsd2a), a primary DHA transporter. Mfsd2a also serves as a major regulator of transcytosis during development, and a reduction in Mfsd2a levels poses a major risk for the development of leaky blood vessels.  Conclusion: Impairment of the blood-retinal barrier (BRB) is associated with the development of numerous ocular diseases, and a better understanding of how to manipulate transcytosis in the BRB during development can enhance drug delivery through the BRB or contribute to the repair of central nervous system (CNS) barriers.
T2  - Frontiers in Nutrition
T1  - The supplementation of a high dose of fish oil during pregnancy and lactation led to an elevation in Mfsd2a expression without any changes in docosahexaenoic acid levels in the retina of healthy 2-month-old mouse offspring
VL  - 10
SP  - 1330414
DO  - 10.3389/fnut.2023.1330414
ER  - 

@article{
author = "Jovanović Macura, Irena and Đuričić, Ivana and Major, Tamara and Milanović, Desanka and Šobajić, Slađana and Kanazir, Selma and Ivković, Sanja",
year = "2024",
abstract = "Introduction: During fetal development, the proper development of neural and visual systems relies on the maternal supplementation of omega-3 fatty acids through placental transfer. Pregnant women are strongly advised to augment their diet with additional sources of omega-3, such as fish oil (FO). This supplementation has been linked to a reduced risk of preterm birth, pre-eclampsia, and perinatal depression. Recently, higher doses of omega-3 supplementation have been recommended for pregnant women. Considering that omega-3 fatty acids, particularly docosahexaenoic acid (DHA), play a crucial role in maintaining the delicate homeostasis required for the proper functioning of the retina and photoreceptors the effects of high-dose fish oil (FO) supplementation during pregnancy and lactation on the retina and retinal pigmented epithelium (RPE) in healthy offspring warrant better understanding.  Methods: The fatty acid content and the changes in the expression of the genes regulating cholesterol homeostasis and DHA transport in the retina and RPE were evaluated following the high-dose FO supplementation.  Results: Our study demonstrated that despite the high-dose FO treatment during pregnancy and lactation, the rigorous DHA homeostasis in the retina and RPE of the two-month-old offspring remained balanced. Another significant finding of this study is the increase in the expression levels of major facilitator superfamily domain-containing protein (Mfsd2a), a primary DHA transporter. Mfsd2a also serves as a major regulator of transcytosis during development, and a reduction in Mfsd2a levels poses a major risk for the development of leaky blood vessels.  Conclusion: Impairment of the blood-retinal barrier (BRB) is associated with the development of numerous ocular diseases, and a better understanding of how to manipulate transcytosis in the BRB during development can enhance drug delivery through the BRB or contribute to the repair of central nervous system (CNS) barriers.",
journal = "Frontiers in Nutrition",
title = "The supplementation of a high dose of fish oil during pregnancy and lactation led to an elevation in Mfsd2a expression without any changes in docosahexaenoic acid levels in the retina of healthy 2-month-old mouse offspring",
volume = "10",
pages = "1330414",
doi = "10.3389/fnut.2023.1330414"
}

Jovanović Macura, I., Đuričić, I., Major, T., Milanović, D., Šobajić, S., Kanazir, S.,& Ivković, S.. (2024). The supplementation of a high dose of fish oil during pregnancy and lactation led to an elevation in Mfsd2a expression without any changes in docosahexaenoic acid levels in the retina of healthy 2-month-old mouse offspring. in Frontiers in Nutrition, 10, 1330414.
https://doi.org/10.3389/fnut.2023.1330414

Jovanović Macura I, Đuričić I, Major T, Milanović D, Šobajić S, Kanazir S, Ivković S. The supplementation of a high dose of fish oil during pregnancy and lactation led to an elevation in Mfsd2a expression without any changes in docosahexaenoic acid levels in the retina of healthy 2-month-old mouse offspring. in Frontiers in Nutrition. 2024;10:1330414.
doi:10.3389/fnut.2023.1330414 .

Jovanović Macura, Irena, Đuričić, Ivana, Major, Tamara, Milanović, Desanka, Šobajić, Slađana, Kanazir, Selma, Ivković, Sanja, "The supplementation of a high dose of fish oil during pregnancy and lactation led to an elevation in Mfsd2a expression without any changes in docosahexaenoic acid levels in the retina of healthy 2-month-old mouse offspring" in Frontiers in Nutrition, 10 (2024):1330414,
https://doi.org/10.3389/fnut.2023.1330414 . .

TY  - JOUR
AU  - Dragićević, Nina
AU  - Predić-Atkinson, Jelena
AU  - Nikolić, Bojan
AU  - Pajović, Snežana B.
AU  - Ivković, Sanja
AU  - Adžić, Miroslav
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12828
AB  - Introduction  Photodynamic therapy (PDT) has gained significant attention due to its superiority over conventional treatments. In the context of skin cancers and nonmalignant skin diseases, topical application of photosensitizer formulations onto affected skin, followed by illumination, offers distinct advantages. Topical PDT simplifies therapy by providing easy access to the skin, increasing drug concentration within the target area, and confining residual photosensitivity to the treated skin. However, the effectiveness of topical PDT is often hindered by challenges such as limited skin penetration or photosensitizer instability. Additionally, the hypoxic tumor environment poses further limitations. Nanocarriers present a promising solution to address these challenges. Areas covered  The objective of this review is to comprehensively explore and highlight the role of various nanocarriers in advancing topical PDT for the treatment of skin diseases. The primary focus is to address the challenges associated with conventional topical PDT approaches and demonstrate how nanotechnology-based strategies can overcome these challenges, thereby improving the overall efficiency and efficacy of PDT. Expert opinion  Nanotechnology has revolutionized the field of PDT, offering innovative tools to combat the unfavorable features of photosensitizers and hurdles in PDT. Nanocarriers enhance skin penetration and stability of photosensitizers, provide controlled drug release, reduce needed dose, increase production of reactive oxygen species, while reducing side effects, thereby improving PDT effectiveness.
T2  - Expert Opinion on Drug Delivery
T1  - Nanocarriers in topical photodynamic therapy
VL  - 21
IS  - 2
DO  - 10.1080/17425247.2024.2318460
ER  - 

@article{
author = "Dragićević, Nina and Predić-Atkinson, Jelena and Nikolić, Bojan and Pajović, Snežana B. and Ivković, Sanja and Adžić, Miroslav",
year = "2024",
abstract = "Introduction  Photodynamic therapy (PDT) has gained significant attention due to its superiority over conventional treatments. In the context of skin cancers and nonmalignant skin diseases, topical application of photosensitizer formulations onto affected skin, followed by illumination, offers distinct advantages. Topical PDT simplifies therapy by providing easy access to the skin, increasing drug concentration within the target area, and confining residual photosensitivity to the treated skin. However, the effectiveness of topical PDT is often hindered by challenges such as limited skin penetration or photosensitizer instability. Additionally, the hypoxic tumor environment poses further limitations. Nanocarriers present a promising solution to address these challenges. Areas covered  The objective of this review is to comprehensively explore and highlight the role of various nanocarriers in advancing topical PDT for the treatment of skin diseases. The primary focus is to address the challenges associated with conventional topical PDT approaches and demonstrate how nanotechnology-based strategies can overcome these challenges, thereby improving the overall efficiency and efficacy of PDT. Expert opinion  Nanotechnology has revolutionized the field of PDT, offering innovative tools to combat the unfavorable features of photosensitizers and hurdles in PDT. Nanocarriers enhance skin penetration and stability of photosensitizers, provide controlled drug release, reduce needed dose, increase production of reactive oxygen species, while reducing side effects, thereby improving PDT effectiveness.",
journal = "Expert Opinion on Drug Delivery",
title = "Nanocarriers in topical photodynamic therapy",
volume = "21",
number = "2",
doi = "10.1080/17425247.2024.2318460"
}

Dragićević, N., Predić-Atkinson, J., Nikolić, B., Pajović, S. B., Ivković, S.,& Adžić, M.. (2024). Nanocarriers in topical photodynamic therapy. in Expert Opinion on Drug Delivery, 21(2).
https://doi.org/10.1080/17425247.2024.2318460

Dragićević N, Predić-Atkinson J, Nikolić B, Pajović SB, Ivković S, Adžić M. Nanocarriers in topical photodynamic therapy. in Expert Opinion on Drug Delivery. 2024;21(2).
doi:10.1080/17425247.2024.2318460 .

Dragićević, Nina, Predić-Atkinson, Jelena, Nikolić, Bojan, Pajović, Snežana B., Ivković, Sanja, Adžić, Miroslav, "Nanocarriers in topical photodynamic therapy" in Expert Opinion on Drug Delivery, 21, no. 2 (2024),
https://doi.org/10.1080/17425247.2024.2318460 . .

TY  - JOUR
AU  - Casian-Plaza, F.A.
AU  - Janovszky, P.M.
AU  - Palásti, D.J.
AU  - Kohut, A.
AU  - Geretovszky, Zs.
AU  - Kopniczky, J.
AU  - Schubert, F.
AU  - Živković, Sanja
AU  - Galbács, Z.
AU  - Galbács, G.
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12938
AB  - In this study, we compared the applicability of three nanoparticle deposition techniques (spray coating, spark discharge nanoparticle generation, magnetron sputtering) towards elemental mapping by nanoparticle-enhanced laser-induced breakdown spectroscopy (NE-LIBS). It was found that sputtering followed by a thermal treatment at 550 °C can provide a homogenous, practical and controllable way of NE-LIBS sample preparation with gold nanoparticles. The laser ablation properties of the created NP layer was also studied in detail and it was established that a 200 μm laser spot size is good compromise between the NE-LIBS signal enhancement and the spatial resolution required for mapping. A signal enhancement of about a factor of 10 with good repeatability (ca. 5 %RSD) in a line scanning demonstration was achieved on glass for Si detection. For samples that are fairly temperature and vacuum stable, this approach allows the signal enhancement to be used in mapping applications.
T2  - Applied Surface Science
T1  - Comparison of three nanoparticle deposition techniques potentially applicable to elemental mapping by nanoparticle-enhanced laser-induced breakdown spectroscopy
VL  - 657
SP  - 159844
DO  - 10.1016/j.apsusc.2024.159844
ER  - 

@article{
author = "Casian-Plaza, F.A. and Janovszky, P.M. and Palásti, D.J. and Kohut, A. and Geretovszky, Zs. and Kopniczky, J. and Schubert, F. and Živković, Sanja and Galbács, Z. and Galbács, G.",
year = "2024",
abstract = "In this study, we compared the applicability of three nanoparticle deposition techniques (spray coating, spark discharge nanoparticle generation, magnetron sputtering) towards elemental mapping by nanoparticle-enhanced laser-induced breakdown spectroscopy (NE-LIBS). It was found that sputtering followed by a thermal treatment at 550 °C can provide a homogenous, practical and controllable way of NE-LIBS sample preparation with gold nanoparticles. The laser ablation properties of the created NP layer was also studied in detail and it was established that a 200 μm laser spot size is good compromise between the NE-LIBS signal enhancement and the spatial resolution required for mapping. A signal enhancement of about a factor of 10 with good repeatability (ca. 5 %RSD) in a line scanning demonstration was achieved on glass for Si detection. For samples that are fairly temperature and vacuum stable, this approach allows the signal enhancement to be used in mapping applications.",
journal = "Applied Surface Science",
title = "Comparison of three nanoparticle deposition techniques potentially applicable to elemental mapping by nanoparticle-enhanced laser-induced breakdown spectroscopy",
volume = "657",
pages = "159844",
doi = "10.1016/j.apsusc.2024.159844"
}

Casian-Plaza, F.A., Janovszky, P.M., Palásti, D.J., Kohut, A., Geretovszky, Zs., Kopniczky, J., Schubert, F., Živković, S., Galbács, Z.,& Galbács, G.. (2024). Comparison of three nanoparticle deposition techniques potentially applicable to elemental mapping by nanoparticle-enhanced laser-induced breakdown spectroscopy. in Applied Surface Science, 657, 159844.
https://doi.org/10.1016/j.apsusc.2024.159844

Casian-Plaza F, Janovszky P, Palásti D, Kohut A, Geretovszky Z, Kopniczky J, Schubert F, Živković S, Galbács Z, Galbács G. Comparison of three nanoparticle deposition techniques potentially applicable to elemental mapping by nanoparticle-enhanced laser-induced breakdown spectroscopy. in Applied Surface Science. 2024;657:159844.
doi:10.1016/j.apsusc.2024.159844 .

Casian-Plaza, F.A., Janovszky, P.M., Palásti, D.J., Kohut, A., Geretovszky, Zs., Kopniczky, J., Schubert, F., Živković, Sanja, Galbács, Z., Galbács, G., "Comparison of three nanoparticle deposition techniques potentially applicable to elemental mapping by nanoparticle-enhanced laser-induced breakdown spectroscopy" in Applied Surface Science, 657 (2024):159844,
https://doi.org/10.1016/j.apsusc.2024.159844 . .

TY  - JOUR
AU  - Jovičić, Katarina
AU  - Đikanović, Vesna
AU  - Santrač, Isidora
AU  - Živković, Sanja
AU  - Dimitrijević, Milena
AU  - Vranković, Jelena S.
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/13023
AB  - Anthropogenic pollution poses a major threat to aquatic ecosystems, which can lead to their degradation. The accumulation and toxicity of metals and trace elements in fish leads to physiological and chemical changes in the fish body. In this study, we investigated the effects of bioaccumulation of metals and trace elements on freshwater fish fatty acid profiles at two different sites before and after the discharge of untreated municipal wastewater in two fish species with different diet habits. Although the concentrations of toxic elements were below the maximum levels proposed by the EU and the Republic of Serbia, this study showed statistically significant correlations between the presence of certain elements and the fatty acid (FA) profile in fish muscle. Lower concentrations of polyunsaturated FA in fish sampled after the discharge of untreated municipal wastewater were detected.
AB  - In this study, the concentrations of metals and trace elements (As, Cd, Co, Cr, Cu, Hg, Ni, Pb and Zn) were determined in the muscle tissue of adult roach and white bream at two different sites in the Belgrade section of the Danube. Twenty-six fatty acids, consisting of nine saturated FA (SFAs), seven monosaturated FA (MUFAs) and ten polysaturated FA (PUFAs), were identified. The analysis of the concentration of metals and trace elements of the roach and white bream showed species-specific differences in their bioaccumulation. Four of all elements analyzed (As, Hg, Ni and Pb) correlated significantly with the changes in FA profiles in fish from both sampling sites, with the exception of Cu, which correlated with the FA profile at the site before, and Zn, whose concentration influenced the FA profile at the site after wastewater discharges. The lower PUFA content in the fish from a site under higher environment pressure could indicate that the fish are stressed. The results suggest that changes in lipid composition may be one of the protective mechanisms of cells to cope with anthropogenic stressors.
T2  - Animals
T1  - Effects of Trace Elements on the Fatty Acid Composition in Danubian Fish Species
VL  - 14
IS  - 6
SP  - 954
DO  - 10.3390/ani14060954
ER  - 

@article{
author = "Jovičić, Katarina and Đikanović, Vesna and Santrač, Isidora and Živković, Sanja and Dimitrijević, Milena and Vranković, Jelena S.",
year = "2024",
abstract = "Anthropogenic pollution poses a major threat to aquatic ecosystems, which can lead to their degradation. The accumulation and toxicity of metals and trace elements in fish leads to physiological and chemical changes in the fish body. In this study, we investigated the effects of bioaccumulation of metals and trace elements on freshwater fish fatty acid profiles at two different sites before and after the discharge of untreated municipal wastewater in two fish species with different diet habits. Although the concentrations of toxic elements were below the maximum levels proposed by the EU and the Republic of Serbia, this study showed statistically significant correlations between the presence of certain elements and the fatty acid (FA) profile in fish muscle. Lower concentrations of polyunsaturated FA in fish sampled after the discharge of untreated municipal wastewater were detected., In this study, the concentrations of metals and trace elements (As, Cd, Co, Cr, Cu, Hg, Ni, Pb and Zn) were determined in the muscle tissue of adult roach and white bream at two different sites in the Belgrade section of the Danube. Twenty-six fatty acids, consisting of nine saturated FA (SFAs), seven monosaturated FA (MUFAs) and ten polysaturated FA (PUFAs), were identified. The analysis of the concentration of metals and trace elements of the roach and white bream showed species-specific differences in their bioaccumulation. Four of all elements analyzed (As, Hg, Ni and Pb) correlated significantly with the changes in FA profiles in fish from both sampling sites, with the exception of Cu, which correlated with the FA profile at the site before, and Zn, whose concentration influenced the FA profile at the site after wastewater discharges. The lower PUFA content in the fish from a site under higher environment pressure could indicate that the fish are stressed. The results suggest that changes in lipid composition may be one of the protective mechanisms of cells to cope with anthropogenic stressors.",
journal = "Animals",
title = "Effects of Trace Elements on the Fatty Acid Composition in Danubian Fish Species",
volume = "14",
number = "6",
pages = "954",
doi = "10.3390/ani14060954"
}

Jovičić, K., Đikanović, V., Santrač, I., Živković, S., Dimitrijević, M.,& Vranković, J. S.. (2024). Effects of Trace Elements on the Fatty Acid Composition in Danubian Fish Species. in Animals, 14(6), 954.
https://doi.org/10.3390/ani14060954

Jovičić K, Đikanović V, Santrač I, Živković S, Dimitrijević M, Vranković JS. Effects of Trace Elements on the Fatty Acid Composition in Danubian Fish Species. in Animals. 2024;14(6):954.
doi:10.3390/ani14060954 .

Jovičić, Katarina, Đikanović, Vesna, Santrač, Isidora, Živković, Sanja, Dimitrijević, Milena, Vranković, Jelena S., "Effects of Trace Elements on the Fatty Acid Composition in Danubian Fish Species" in Animals, 14, no. 6 (2024):954,
https://doi.org/10.3390/ani14060954 . .

TY  - JOUR
AU  - Ivković, Sanja
AU  - Koruga, Đuro
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/13101
T2  - Neural Regeneration Research
T1  - Role of fullerenols derivative 3HFWC in the treatment of Alzheimer's disease
VL  - 19
IS  - 8
SP  - 1641
EP  - 1642
DO  - 10.4103/1673-5374.389641
ER  - 

@article{
author = "Ivković, Sanja and Koruga, Đuro",
year = "2024",
journal = "Neural Regeneration Research",
title = "Role of fullerenols derivative 3HFWC in the treatment of Alzheimer's disease",
volume = "19",
number = "8",
pages = "1641-1642",
doi = "10.4103/1673-5374.389641"
}

Ivković, S.,& Koruga, Đ.. (2024). Role of fullerenols derivative 3HFWC in the treatment of Alzheimer's disease. in Neural Regeneration Research, 19(8), 1641-1642.
https://doi.org/10.4103/1673-5374.389641

Ivković S, Koruga Đ. Role of fullerenols derivative 3HFWC in the treatment of Alzheimer's disease. in Neural Regeneration Research. 2024;19(8):1641-1642.
doi:10.4103/1673-5374.389641 .

Ivković, Sanja, Koruga, Đuro, "Role of fullerenols derivative 3HFWC in the treatment of Alzheimer's disease" in Neural Regeneration Research, 19, no. 8 (2024):1641-1642,
https://doi.org/10.4103/1673-5374.389641 . .

TY  - JOUR
AU  - Vasović, Dolika D.
AU  - Ivković, Sanja
AU  - Živanović, Ana
AU  - Major, Tamara
AU  - Milašin, Jelena M.
AU  - Nikolić, Nađa S.
AU  - Simonović, Jelena
AU  - Šutulović, Nikola
AU  - Hrnčić, Dragan
AU  - Stanojlović, Olivera
AU  - Vesković, Milena
AU  - Rašić, Dejan M.
AU  - Mladenović, Dušan
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/13177
AB  - Diabetic retinopathy is not cured efficiently and changes of lifestyle measures may delay early retinal injury indiabetes. The aim of our study was to investigate the effects of reduced daily light exposure on retinal vascularchanges in streptozotocin (STZ)-induced model of DM with emphasis on inflammation, Aqp4 expression, visualcycle and cholesterol metabolism-related gene expression in rat retina and RPE. Male Wistar rats were dividedinto the following groups: 1. control; 2. diabetic group (DM) treated with streptozotocin (100 mg/kg); 3. groupexposed to light/dark cycle 6/18 h (6/18); 4. diabetic group exposed to light/dark cycle 6/18 h (DM+6/18).Retinal vascular abnormalities were estimated based on lectin staining, while the expression of genes involved inthe visual cycle, cholesterol metabolism, and inflammation was determined by qRT-PCR. Reduced light exposurealleviated vasculopathy, gliosis and the expression of IL-1 and TNF-α in the retina with increased perivascularAqp4 expression. The expression of genes involved in visual cycle and cholesterol metabolism was significantlyup-regulated in RPE in DM+6/18 vs. DM group. In the retina only the expression of APOE was significantlyhigher in DM+6/18 vs. DM group. Reduced light exposure mitigates vascular changes and gliosis in DM via itsanti-inflammatory effect, increased retinal cholesterol turnover and perivascular Aqp4 expression.
T2  - Chemico-Biological Interactions
T1  - Reduced light exposure mitigates streptozotocin-induced vascular changes and gliosis in diabetic retina by an anti-inflammatory effect and increased retinal cholesterol turnover
VL  - 394
SP  - 110996
DO  - 10.1016/j.cbi.2024.110996
ER  - 

@article{
author = "Vasović, Dolika D. and Ivković, Sanja and Živanović, Ana and Major, Tamara and Milašin, Jelena M. and Nikolić, Nađa S. and Simonović, Jelena and Šutulović, Nikola and Hrnčić, Dragan and Stanojlović, Olivera and Vesković, Milena and Rašić, Dejan M. and Mladenović, Dušan",
year = "2024",
abstract = "Diabetic retinopathy is not cured efficiently and changes of lifestyle measures may delay early retinal injury indiabetes. The aim of our study was to investigate the effects of reduced daily light exposure on retinal vascularchanges in streptozotocin (STZ)-induced model of DM with emphasis on inflammation, Aqp4 expression, visualcycle and cholesterol metabolism-related gene expression in rat retina and RPE. Male Wistar rats were dividedinto the following groups: 1. control; 2. diabetic group (DM) treated with streptozotocin (100 mg/kg); 3. groupexposed to light/dark cycle 6/18 h (6/18); 4. diabetic group exposed to light/dark cycle 6/18 h (DM+6/18).Retinal vascular abnormalities were estimated based on lectin staining, while the expression of genes involved inthe visual cycle, cholesterol metabolism, and inflammation was determined by qRT-PCR. Reduced light exposurealleviated vasculopathy, gliosis and the expression of IL-1 and TNF-α in the retina with increased perivascularAqp4 expression. The expression of genes involved in visual cycle and cholesterol metabolism was significantlyup-regulated in RPE in DM+6/18 vs. DM group. In the retina only the expression of APOE was significantlyhigher in DM+6/18 vs. DM group. Reduced light exposure mitigates vascular changes and gliosis in DM via itsanti-inflammatory effect, increased retinal cholesterol turnover and perivascular Aqp4 expression.",
journal = "Chemico-Biological Interactions",
title = "Reduced light exposure mitigates streptozotocin-induced vascular changes and gliosis in diabetic retina by an anti-inflammatory effect and increased retinal cholesterol turnover",
volume = "394",
pages = "110996",
doi = "10.1016/j.cbi.2024.110996"
}

Vasović, D. D., Ivković, S., Živanović, A., Major, T., Milašin, J. M., Nikolić, N. S., Simonović, J., Šutulović, N., Hrnčić, D., Stanojlović, O., Vesković, M., Rašić, D. M.,& Mladenović, D.. (2024). Reduced light exposure mitigates streptozotocin-induced vascular changes and gliosis in diabetic retina by an anti-inflammatory effect and increased retinal cholesterol turnover. in Chemico-Biological Interactions, 394, 110996.
https://doi.org/10.1016/j.cbi.2024.110996

Vasović DD, Ivković S, Živanović A, Major T, Milašin JM, Nikolić NS, Simonović J, Šutulović N, Hrnčić D, Stanojlović O, Vesković M, Rašić DM, Mladenović D. Reduced light exposure mitigates streptozotocin-induced vascular changes and gliosis in diabetic retina by an anti-inflammatory effect and increased retinal cholesterol turnover. in Chemico-Biological Interactions. 2024;394:110996.
doi:10.1016/j.cbi.2024.110996 .

Vasović, Dolika D., Ivković, Sanja, Živanović, Ana, Major, Tamara, Milašin, Jelena M., Nikolić, Nađa S., Simonović, Jelena, Šutulović, Nikola, Hrnčić, Dragan, Stanojlović, Olivera, Vesković, Milena, Rašić, Dejan M., Mladenović, Dušan, "Reduced light exposure mitigates streptozotocin-induced vascular changes and gliosis in diabetic retina by an anti-inflammatory effect and increased retinal cholesterol turnover" in Chemico-Biological Interactions, 394 (2024):110996,
https://doi.org/10.1016/j.cbi.2024.110996 . .

TY  - JOUR
AU  - Glavonić, Emilija
AU  - Dragić, Milorad
AU  - Mitić, Miloš
AU  - Aleksić, Minja
AU  - Lukić, Iva
AU  - Ivković, Sanja
AU  - Adžić, Miroslav
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/13259
AB  - Fear-related disorders, including post-traumatic stress disorder (PTSD), and anxiety disorders are pervasive psychiatric conditions marked by persistent fear, stemming from its dysregulated acquisition and extinction. The primary treatment for these disorders, exposure therapy (ET), relies heavily on fear extinction (FE) principles. Adolescence, a vulnerable period for developing psychiatric disorders, is characterized by neurobiological changes in the fear circuitry, leading to impaired FE and increased susceptibility to relapse following ET. Ketamine, known for relieving anxiety and reducing PTSD symptoms, influences fear-related learning processes and synaptic plasticity across the fear circuitry. Our study aimed to investigate the effects of ketamine (10 mg/kg) on FE in adolescent male C57 BL/6 mice at the behavioral and molecular levels. We analyzed the protein and gene expression of synaptic plasticity markers in the hippocampus (HPC) and prefrontal cortex (PFC) and sought to identify neural correlates associated with ketamine’s effects on adolescent extinction learning. Ketamine ameliorated FE in the adolescent males, likely affecting the consolidation and/or recall of extinction memory. Ketamine also increased the Akt and mTOR activity and the GluA1 and GluN2A levels in the HPC and upregulated BDNF exon IV mRNA expression in the HPC and PFC of the fear-extinguished mice. Furthermore, ketamine increased the c-Fos expression in specific brain regions, including the ventral HPC (vHPC) and the left infralimbic ventromedial PFC (IL vmPFC). Providing a comprehensive exploration of ketamine’s mechanisms in adolescent FE, our study suggests that ketamine’s effects on FE in adolescent males are associated with the activation of hippocampal Akt-mTOR-GluA1 signaling, with the vHPC and the left IL vmPFC as the proposed neural correlates.
T2  - Pharmaceuticals
T1  - Ketamine’s Amelioration of Fear Extinction in Adolescent Male Mice Is Associated with the Activation of the Hippocampal Akt-mTOR-GluA1 Pathway
VL  - 17
IS  - 6
SP  - 669
DO  - 10.3390/ph17060669
ER  - 

@article{
author = "Glavonić, Emilija and Dragić, Milorad and Mitić, Miloš and Aleksić, Minja and Lukić, Iva and Ivković, Sanja and Adžić, Miroslav",
year = "2024",
abstract = "Fear-related disorders, including post-traumatic stress disorder (PTSD), and anxiety disorders are pervasive psychiatric conditions marked by persistent fear, stemming from its dysregulated acquisition and extinction. The primary treatment for these disorders, exposure therapy (ET), relies heavily on fear extinction (FE) principles. Adolescence, a vulnerable period for developing psychiatric disorders, is characterized by neurobiological changes in the fear circuitry, leading to impaired FE and increased susceptibility to relapse following ET. Ketamine, known for relieving anxiety and reducing PTSD symptoms, influences fear-related learning processes and synaptic plasticity across the fear circuitry. Our study aimed to investigate the effects of ketamine (10 mg/kg) on FE in adolescent male C57 BL/6 mice at the behavioral and molecular levels. We analyzed the protein and gene expression of synaptic plasticity markers in the hippocampus (HPC) and prefrontal cortex (PFC) and sought to identify neural correlates associated with ketamine’s effects on adolescent extinction learning. Ketamine ameliorated FE in the adolescent males, likely affecting the consolidation and/or recall of extinction memory. Ketamine also increased the Akt and mTOR activity and the GluA1 and GluN2A levels in the HPC and upregulated BDNF exon IV mRNA expression in the HPC and PFC of the fear-extinguished mice. Furthermore, ketamine increased the c-Fos expression in specific brain regions, including the ventral HPC (vHPC) and the left infralimbic ventromedial PFC (IL vmPFC). Providing a comprehensive exploration of ketamine’s mechanisms in adolescent FE, our study suggests that ketamine’s effects on FE in adolescent males are associated with the activation of hippocampal Akt-mTOR-GluA1 signaling, with the vHPC and the left IL vmPFC as the proposed neural correlates.",
journal = "Pharmaceuticals",
title = "Ketamine’s Amelioration of Fear Extinction in Adolescent Male Mice Is Associated with the Activation of the Hippocampal Akt-mTOR-GluA1 Pathway",
volume = "17",
number = "6",
pages = "669",
doi = "10.3390/ph17060669"
}

Glavonić, E., Dragić, M., Mitić, M., Aleksić, M., Lukić, I., Ivković, S.,& Adžić, M.. (2024). Ketamine’s Amelioration of Fear Extinction in Adolescent Male Mice Is Associated with the Activation of the Hippocampal Akt-mTOR-GluA1 Pathway. in Pharmaceuticals, 17(6), 669.
https://doi.org/10.3390/ph17060669

Glavonić E, Dragić M, Mitić M, Aleksić M, Lukić I, Ivković S, Adžić M. Ketamine’s Amelioration of Fear Extinction in Adolescent Male Mice Is Associated with the Activation of the Hippocampal Akt-mTOR-GluA1 Pathway. in Pharmaceuticals. 2024;17(6):669.
doi:10.3390/ph17060669 .

Glavonić, Emilija, Dragić, Milorad, Mitić, Miloš, Aleksić, Minja, Lukić, Iva, Ivković, Sanja, Adžić, Miroslav, "Ketamine’s Amelioration of Fear Extinction in Adolescent Male Mice Is Associated with the Activation of the Hippocampal Akt-mTOR-GluA1 Pathway" in Pharmaceuticals, 17, no. 6 (2024):669,
https://doi.org/10.3390/ph17060669 . .

TY  - JOUR
AU  - Kandić, Irina
AU  - Kragović, Milan M.
AU  - Živković, Sanja
AU  - Knežević, Jelena
AU  - Vuletić, Stefana
AU  - Cvetković, Stefana
AU  - Stojmenović, Marija
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/13464
AB  - Harmful cyanobacteria blooms and the escalating impact of cyanotoxins necessitates the effective removal of cyanobacteria from water ecosystems before they release cyanotoxins. In this study, cyanobacteria removal from water samples taken from the eutrophic Aleksandrovac Lake (southern Serbia) was investigated. For that purpose, novel activated carbons derived from waste biomass—date palm leaf stalk (P_AC), black alder cone-like flowers (A_AC), and commercial activated carbon from coconut shell (C_AC) as a reference were used. To define the best adsorption conditions and explain the adsorption mechanism, the influence of contact time, reaction volume, and adsorbent mass, as well as FTIR analysis of the adsorbents before and after cyanobacteria removal, were studied. The removal efficiency of P_AC and A_AC achieved for the applied concentration of 10 mg/mL after 15 min was ~99%, while for C_AC after 24 h was only ~92% for the same concentration. To check the safety of the applied materials for human health and the environment, the concentrations of potentially toxic elements (PTEs), the health impact (HI) after water purification, and the toxicity (MTT and Comet assay) of the materials were evaluated. Although the P_AC and A_AC achieved much better removal properties in comparison with the C_AC, considering the demonstrated genotoxicity and cytotoxicity of the P_AC and the higher HI value for the C_AC, only the A_AC was further investigated. Results of the kinetics, FTIR analysis, and examination of the A_AC mass influence on removal efficiency indicated dominance of the physisorption mechanism. Initially, the findings highlighted the superior performance of A_AC, with great potential to be globally commercialized as an effective cyanobacteria cell adsorbent.
T2  - Toxins
T1  - Kinetics and Mechanism of Cyanobacteria Cell Removal Using Biowaste-Derived Activated Carbons with Assessment of Potential Human Health Impacts
VL  - 16
IS  - 7
SP  - 310
DO  - 10.3390/toxins16070310
ER  - 

@article{
author = "Kandić, Irina and Kragović, Milan M. and Živković, Sanja and Knežević, Jelena and Vuletić, Stefana and Cvetković, Stefana and Stojmenović, Marija",
year = "2024",
abstract = "Harmful cyanobacteria blooms and the escalating impact of cyanotoxins necessitates the effective removal of cyanobacteria from water ecosystems before they release cyanotoxins. In this study, cyanobacteria removal from water samples taken from the eutrophic Aleksandrovac Lake (southern Serbia) was investigated. For that purpose, novel activated carbons derived from waste biomass—date palm leaf stalk (P_AC), black alder cone-like flowers (A_AC), and commercial activated carbon from coconut shell (C_AC) as a reference were used. To define the best adsorption conditions and explain the adsorption mechanism, the influence of contact time, reaction volume, and adsorbent mass, as well as FTIR analysis of the adsorbents before and after cyanobacteria removal, were studied. The removal efficiency of P_AC and A_AC achieved for the applied concentration of 10 mg/mL after 15 min was ~99%, while for C_AC after 24 h was only ~92% for the same concentration. To check the safety of the applied materials for human health and the environment, the concentrations of potentially toxic elements (PTEs), the health impact (HI) after water purification, and the toxicity (MTT and Comet assay) of the materials were evaluated. Although the P_AC and A_AC achieved much better removal properties in comparison with the C_AC, considering the demonstrated genotoxicity and cytotoxicity of the P_AC and the higher HI value for the C_AC, only the A_AC was further investigated. Results of the kinetics, FTIR analysis, and examination of the A_AC mass influence on removal efficiency indicated dominance of the physisorption mechanism. Initially, the findings highlighted the superior performance of A_AC, with great potential to be globally commercialized as an effective cyanobacteria cell adsorbent.",
journal = "Toxins",
title = "Kinetics and Mechanism of Cyanobacteria Cell Removal Using Biowaste-Derived Activated Carbons with Assessment of Potential Human Health Impacts",
volume = "16",
number = "7",
pages = "310",
doi = "10.3390/toxins16070310"
}

Kandić, I., Kragović, M. M., Živković, S., Knežević, J., Vuletić, S., Cvetković, S.,& Stojmenović, M.. (2024). Kinetics and Mechanism of Cyanobacteria Cell Removal Using Biowaste-Derived Activated Carbons with Assessment of Potential Human Health Impacts. in Toxins, 16(7), 310.
https://doi.org/10.3390/toxins16070310

Kandić I, Kragović MM, Živković S, Knežević J, Vuletić S, Cvetković S, Stojmenović M. Kinetics and Mechanism of Cyanobacteria Cell Removal Using Biowaste-Derived Activated Carbons with Assessment of Potential Human Health Impacts. in Toxins. 2024;16(7):310.
doi:10.3390/toxins16070310 .

Kandić, Irina, Kragović, Milan M., Živković, Sanja, Knežević, Jelena, Vuletić, Stefana, Cvetković, Stefana, Stojmenović, Marija, "Kinetics and Mechanism of Cyanobacteria Cell Removal Using Biowaste-Derived Activated Carbons with Assessment of Potential Human Health Impacts" in Toxins, 16, no. 7 (2024):310,
https://doi.org/10.3390/toxins16070310 . .

TY  - JOUR
AU  - Tošić, Miloš
AU  - Savić, Jasmina
AU  - Valenta Šobot, Ana
AU  - Živković, Sanja
AU  - Dimitrijević, Aleksandra
AU  - Ilić, Nevena
AU  - Dimitrijević-Branković, Suzana
AU  - Momčilović, Miloš
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/13633
AB  - This study investigates the impact of changing parameters on the photocatalytic degradation of carbofuran (CBF) using laser-treated TiO2 nanotube arrays on a Ti mesh under simulated sunlight irradiation and assessing toxicity during photocatalytic degradation. Various parameters, including the stirring effect, light intensity, initial CBF concentration, and variation in the active surface area of laser-treated TiO2 photocatalysts, were examined to determine their impact on degradation efficiency. The photodegradation kinetics were monitored using ultra-performance liquid chromatography with a PDA detector (UPLC-PDA) and UV-Vis spectrophotometry, while mineralization was assessed by a total organic carbon (TOC) analyzer. The photocatalytic degradation of CBF is enhanced by an increase in the active surface area of the TiO2 photocatalyst, light intensity, and the introduction of stirring, but it decreases with an increase in the initial concentration of CBF. The toxicity assessments revealed that the cytotoxicity of CBF initially increased during the degradation process but decreased after further treatment, indicating the formation and subsequent breakdown of toxic intermediates. The phytotoxicity test showed that longer degradation times resulted in higher toxicity to plant growth. This study provides new insights into the photocatalytic degradation of CBF with TiO2, the importance of parameter optimization for more efficient treatment, and the use of toxicity tests to confirm the success of the photocatalytic process
T2  - Toxics
T1  - Photocatalytic Degradation of Carbofuran in Water Using Laser-Treated TiO2: Parameters Influence Study, Cyto- and Phytotoxicity Assessment
VL  - 12
IS  - 8
SP  - 566
DO  - 10.3390/toxics12080566
ER  - 

@article{
author = "Tošić, Miloš and Savić, Jasmina and Valenta Šobot, Ana and Živković, Sanja and Dimitrijević, Aleksandra and Ilić, Nevena and Dimitrijević-Branković, Suzana and Momčilović, Miloš",
year = "2024",
abstract = "This study investigates the impact of changing parameters on the photocatalytic degradation of carbofuran (CBF) using laser-treated TiO2 nanotube arrays on a Ti mesh under simulated sunlight irradiation and assessing toxicity during photocatalytic degradation. Various parameters, including the stirring effect, light intensity, initial CBF concentration, and variation in the active surface area of laser-treated TiO2 photocatalysts, were examined to determine their impact on degradation efficiency. The photodegradation kinetics were monitored using ultra-performance liquid chromatography with a PDA detector (UPLC-PDA) and UV-Vis spectrophotometry, while mineralization was assessed by a total organic carbon (TOC) analyzer. The photocatalytic degradation of CBF is enhanced by an increase in the active surface area of the TiO2 photocatalyst, light intensity, and the introduction of stirring, but it decreases with an increase in the initial concentration of CBF. The toxicity assessments revealed that the cytotoxicity of CBF initially increased during the degradation process but decreased after further treatment, indicating the formation and subsequent breakdown of toxic intermediates. The phytotoxicity test showed that longer degradation times resulted in higher toxicity to plant growth. This study provides new insights into the photocatalytic degradation of CBF with TiO2, the importance of parameter optimization for more efficient treatment, and the use of toxicity tests to confirm the success of the photocatalytic process",
journal = "Toxics",
title = "Photocatalytic Degradation of Carbofuran in Water Using Laser-Treated TiO2: Parameters Influence Study, Cyto- and Phytotoxicity Assessment",
volume = "12",
number = "8",
pages = "566",
doi = "10.3390/toxics12080566"
}

Tošić, M., Savić, J., Valenta Šobot, A., Živković, S., Dimitrijević, A., Ilić, N., Dimitrijević-Branković, S.,& Momčilović, M.. (2024). Photocatalytic Degradation of Carbofuran in Water Using Laser-Treated TiO2: Parameters Influence Study, Cyto- and Phytotoxicity Assessment. in Toxics, 12(8), 566.
https://doi.org/10.3390/toxics12080566

Tošić M, Savić J, Valenta Šobot A, Živković S, Dimitrijević A, Ilić N, Dimitrijević-Branković S, Momčilović M. Photocatalytic Degradation of Carbofuran in Water Using Laser-Treated TiO2: Parameters Influence Study, Cyto- and Phytotoxicity Assessment. in Toxics. 2024;12(8):566.
doi:10.3390/toxics12080566 .

Tošić, Miloš, Savić, Jasmina, Valenta Šobot, Ana, Živković, Sanja, Dimitrijević, Aleksandra, Ilić, Nevena, Dimitrijević-Branković, Suzana, Momčilović, Miloš, "Photocatalytic Degradation of Carbofuran in Water Using Laser-Treated TiO2: Parameters Influence Study, Cyto- and Phytotoxicity Assessment" in Toxics, 12, no. 8 (2024):566,
https://doi.org/10.3390/toxics12080566 . .

TY  - JOUR
AU  - Srejić, Irina
AU  - Maksić, Aleksandar
AU  - Novaković, Mirjana
AU  - Potočnik, Jelena
AU  - Rakočević, Lazar
AU  - Živković, Sanja
AU  - Smiljanić, Milutin
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/13745
AB  - Securing ever-increasing energy demands while reducing resilience on fossil fuels is a major task of modern society. Fuel cells are devices in which the chemical energy of various fuels can be converted into clean electricity. Direct ethanol fuel cells (DEFC) are increasingly popular for their eco-friendliness and significantly easier liquid fuel manipulation compared to hydrogen-fed fuel cells. Carbon-supported Pt nanoparticles are considered reference catalysts for fuel oxidation in DEFCs. Several challenges hinder DEFC commercialization: high Pt-loading, Pt poisoning by CO intermediates, and the instability of the Pt and carbon supports. This work demonstrates an efficient electrocatalyst for ethanol oxidation reaction (EOR) composed of Pt nanoparticles supported on electrochemically exfoliated graphene (Pt/el-rGO). Graphene was obtained through anodic electrochemical exfoliation using graphitic tape as the anode, while Pt nanoparticles were synthesized using chemical reduction with formic acid. As-obtained Pt/el-rGO with only 7.5 wt.% Pt was characterized using TEM, SEM, and XPS. Pt/el-rGO exhibited notably higher EOR catalytic activity in an alkaline electrolyte than the Pt/C benchmark. This enhancement can be linked with the functional groups present on the graphene support, which facilitate ethanol dehydrogenation as the first step in the EOR mechanism and thus enhance reaction kinetics on Pt-active sites.
T2  - Sustainability
T1  - Low-Loaded Pt Nanoparticles Supported on Electrochemically Exfoliated Graphene as a Sustainable Catalyst for Electrochemical Ethanol Oxidation
VL  - 16
IS  - 18
SP  - 8189
DO  - 10.3390/su16188189
ER  - 

@article{
author = "Srejić, Irina and Maksić, Aleksandar and Novaković, Mirjana and Potočnik, Jelena and Rakočević, Lazar and Živković, Sanja and Smiljanić, Milutin",
year = "2024",
abstract = "Securing ever-increasing energy demands while reducing resilience on fossil fuels is a major task of modern society. Fuel cells are devices in which the chemical energy of various fuels can be converted into clean electricity. Direct ethanol fuel cells (DEFC) are increasingly popular for their eco-friendliness and significantly easier liquid fuel manipulation compared to hydrogen-fed fuel cells. Carbon-supported Pt nanoparticles are considered reference catalysts for fuel oxidation in DEFCs. Several challenges hinder DEFC commercialization: high Pt-loading, Pt poisoning by CO intermediates, and the instability of the Pt and carbon supports. This work demonstrates an efficient electrocatalyst for ethanol oxidation reaction (EOR) composed of Pt nanoparticles supported on electrochemically exfoliated graphene (Pt/el-rGO). Graphene was obtained through anodic electrochemical exfoliation using graphitic tape as the anode, while Pt nanoparticles were synthesized using chemical reduction with formic acid. As-obtained Pt/el-rGO with only 7.5 wt.% Pt was characterized using TEM, SEM, and XPS. Pt/el-rGO exhibited notably higher EOR catalytic activity in an alkaline electrolyte than the Pt/C benchmark. This enhancement can be linked with the functional groups present on the graphene support, which facilitate ethanol dehydrogenation as the first step in the EOR mechanism and thus enhance reaction kinetics on Pt-active sites.",
journal = "Sustainability",
title = "Low-Loaded Pt Nanoparticles Supported on Electrochemically Exfoliated Graphene as a Sustainable Catalyst for Electrochemical Ethanol Oxidation",
volume = "16",
number = "18",
pages = "8189",
doi = "10.3390/su16188189"
}

Srejić, I., Maksić, A., Novaković, M., Potočnik, J., Rakočević, L., Živković, S.,& Smiljanić, M.. (2024). Low-Loaded Pt Nanoparticles Supported on Electrochemically Exfoliated Graphene as a Sustainable Catalyst for Electrochemical Ethanol Oxidation. in Sustainability, 16(18), 8189.
https://doi.org/10.3390/su16188189

Srejić I, Maksić A, Novaković M, Potočnik J, Rakočević L, Živković S, Smiljanić M. Low-Loaded Pt Nanoparticles Supported on Electrochemically Exfoliated Graphene as a Sustainable Catalyst for Electrochemical Ethanol Oxidation. in Sustainability. 2024;16(18):8189.
doi:10.3390/su16188189 .

Srejić, Irina, Maksić, Aleksandar, Novaković, Mirjana, Potočnik, Jelena, Rakočević, Lazar, Živković, Sanja, Smiljanić, Milutin, "Low-Loaded Pt Nanoparticles Supported on Electrochemically Exfoliated Graphene as a Sustainable Catalyst for Electrochemical Ethanol Oxidation" in Sustainability, 16, no. 18 (2024):8189,
https://doi.org/10.3390/su16188189 . .

TY  - JOUR
AU  - Jovanović Macura, Irena
AU  - Milanović, Desanka
AU  - Tesić, Vesna
AU  - Major, Tamara
AU  - Perović, Milka
AU  - Adžić, Miroslav
AU  - Ivković, Sanja
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/13746
AB  - In patients with Alzheimer’s disease (AD) and in animal models, the increased accumulation of amyloid β (Aβ) in retinal blood vessels strongly correlates with brain amyloid deposits and cognitive decline. The accumulation of Aβ in blood vessels may result from impaired transcytosis and a dysfunctional ocular glymphatic system in AD. High-dose fish oil (FO) supplementation has been shown to significantly change the expression of major facilitator superfamily domain-containing protein 2a (Mfsd2a), a key regulator of transcytosis, and Aquaporin 4 (Aqp4), an essential component of the glymphatic system in the retinas of WT mice. We examined the expression of Mfsd2a and Aqp4 in the retinas of 4-month-old 5xFAD female mice supplemented with high-dose FO for three weeks. There was a significant increase in Mfsd2a expression in 5xFAD retinas supplemented with FO compared to control 5xFAD mice. Additionally, the increase in Aqp4 expression observed in 4-month-old 5xFAD retinas, indicative of an impaired glymphatic system, was significantly decreased. Simultaneously, Aβ accumulation in 5xFAD retinal blood vessels was reduced following FO supplementation. These findings suggest that high-dose FO supplementation could serve as an adjunct in developing new treatments aimed at improving the regulation of transcytosis or the function of the glymphatic system in the AD retina
T2  - International Journal of Molecular Sciences
T1  - The Impact of High-Dose Fish Oil Supplementation on Mfsd2a, Aqp4, and Amyloid-β Expression in Retinal Blood Vessels of 5xFAD Alzheimer’s Mouse Model
VL  - 25
IS  - 17
SP  - 9400
DO  - 10.3390/ijms25179400
ER  - 

@article{
author = "Jovanović Macura, Irena and Milanović, Desanka and Tesić, Vesna and Major, Tamara and Perović, Milka and Adžić, Miroslav and Ivković, Sanja",
year = "2024",
abstract = "In patients with Alzheimer’s disease (AD) and in animal models, the increased accumulation of amyloid β (Aβ) in retinal blood vessels strongly correlates with brain amyloid deposits and cognitive decline. The accumulation of Aβ in blood vessels may result from impaired transcytosis and a dysfunctional ocular glymphatic system in AD. High-dose fish oil (FO) supplementation has been shown to significantly change the expression of major facilitator superfamily domain-containing protein 2a (Mfsd2a), a key regulator of transcytosis, and Aquaporin 4 (Aqp4), an essential component of the glymphatic system in the retinas of WT mice. We examined the expression of Mfsd2a and Aqp4 in the retinas of 4-month-old 5xFAD female mice supplemented with high-dose FO for three weeks. There was a significant increase in Mfsd2a expression in 5xFAD retinas supplemented with FO compared to control 5xFAD mice. Additionally, the increase in Aqp4 expression observed in 4-month-old 5xFAD retinas, indicative of an impaired glymphatic system, was significantly decreased. Simultaneously, Aβ accumulation in 5xFAD retinal blood vessels was reduced following FO supplementation. These findings suggest that high-dose FO supplementation could serve as an adjunct in developing new treatments aimed at improving the regulation of transcytosis or the function of the glymphatic system in the AD retina",
journal = "International Journal of Molecular Sciences",
title = "The Impact of High-Dose Fish Oil Supplementation on Mfsd2a, Aqp4, and Amyloid-β Expression in Retinal Blood Vessels of 5xFAD Alzheimer’s Mouse Model",
volume = "25",
number = "17",
pages = "9400",
doi = "10.3390/ijms25179400"
}

Jovanović Macura, I., Milanović, D., Tesić, V., Major, T., Perović, M., Adžić, M.,& Ivković, S.. (2024). The Impact of High-Dose Fish Oil Supplementation on Mfsd2a, Aqp4, and Amyloid-β Expression in Retinal Blood Vessels of 5xFAD Alzheimer’s Mouse Model. in International Journal of Molecular Sciences, 25(17), 9400.
https://doi.org/10.3390/ijms25179400

Jovanović Macura I, Milanović D, Tesić V, Major T, Perović M, Adžić M, Ivković S. The Impact of High-Dose Fish Oil Supplementation on Mfsd2a, Aqp4, and Amyloid-β Expression in Retinal Blood Vessels of 5xFAD Alzheimer’s Mouse Model. in International Journal of Molecular Sciences. 2024;25(17):9400.
doi:10.3390/ijms25179400 .

Jovanović Macura, Irena, Milanović, Desanka, Tesić, Vesna, Major, Tamara, Perović, Milka, Adžić, Miroslav, Ivković, Sanja, "The Impact of High-Dose Fish Oil Supplementation on Mfsd2a, Aqp4, and Amyloid-β Expression in Retinal Blood Vessels of 5xFAD Alzheimer’s Mouse Model" in International Journal of Molecular Sciences, 25, no. 17 (2024):9400,
https://doi.org/10.3390/ijms25179400 . .

Zhang, H., Sun, Y., Wu, Z., Yin, Y., Liu, R., Zhang, J., Zhang, Z., Yau, S., Wu, H., Yuan, T., Zhang, L., Adžić, M.,& Chen, G.. (2024). Hippocampal PACAP signaling activation triggers a rapid antidepressant response. in Military Medical Research, 11(1), 49.
https://doi.org/10.1186/s40779-024-00548-1

Zhang H, Sun Y, Wu Z, Yin Y, Liu R, Zhang J, Zhang Z, Yau S, Wu H, Yuan T, Zhang L, Adžić M, Chen G. Hippocampal PACAP signaling activation triggers a rapid antidepressant response. in Military Medical Research. 2024;11(1):49.
doi:10.1186/s40779-024-00548-1 .

Zhang, Hai-Lou, Sun, Yan, Wu, Zhang-Jie, Yin, Ying, Liu, Rui-Yi, Zhang, Ji-Chun, Zhang, Zhang-Jin, Yau, Suk-Yu, Wu, Hao-Xin, Yuan, Ti-Fei, Zhang, Li, Adžić, Miroslav, Chen, Gang, "Hippocampal PACAP signaling activation triggers a rapid antidepressant response" in Military Medical Research, 11, no. 1 (2024):49,
https://doi.org/10.1186/s40779-024-00548-1 . .

TY  - JOUR
AU  - Wu, Zhangjie
AU  - Yin, Ying
AU  - Liu, Ruiyi
AU  - Li, Xianhui
AU  - Sun, Yan
AU  - Yau, Suk-yu
AU  - Wu, Lei
AU  - Liu, Yan
AU  - Adžić, Miroslav
AU  - Zhang, Hailou
AU  - Chen, Gang
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/13657
AB  - Ethnopharmacological relevance: Jiawei-Xiaoyao Pill (JWX), a classic formula in traditional Chinese medicine, is derived from Xiaoyao Pill by adding significant amounts of Gardeniae Fructus (GF) and Moutan Cortex (MC). It is frequently used for the treatment of depression. JWX has been demonstrated to uniquely elicit rapid antidepressant-like effects within the prescribed dosage range. To date, GF has been shown to have rapid antidepressant-like effects, but a much higher dose is required than its proportion in JWX. It is assumed that the synergism of GF with a minimum number of other herbs in JWX serves as a refined formula that exerts these rapid antidepressant-like effects. Identification of a refined formula is important for prioritizing the herbs and ingredients to optimize the quality control of JWX. However, such a refined formula for JWX has not been identified yet. Aim of the study: Here we aimed to identify a refined formula derived from JWX for optimized rapid antidepressant-like effects. Since the neuroinflammation mechanism involving in depression treatment has not been previously investigated for JWX, we tested the mechanism for both JWX and the refined formula. Materials and methods: Individual herbs (MC; ASR, Angelica Sinensis Radix; Bupleuri Radix; Paeonia Radix Alba) that show antidepressant-like responses were mixed with GF at the proportional dosage in JWX to identify the refined formula. Rapid antidepressant-like effects were assessed by using NSF (Novelty Suppressed Feeding Test) and other behavioral tests following a single administration. The identified formula was further tested in a lipopolysaccharide (LPS)-induced depressive model, and the molecular signaling mechanisms were investigated using Western blot analysis, immunofluorescence, and pharmacological inhibition of mTOR signaling. Scopolamine (Scop) was used as a positive control for induction of rapid antidepressant effects. Results: A combination of GF, MC and ASR (GMA) at their dosages proportional to JWX induced behavioral signs of rapid antidepressant-like responses in both normal and LPS-treated mice, with the antidepressant-like effects sustained for 5 d. Similar to JWX or Scop, GMA rapidly reduced the neuroinflammation signaling of Iba-1-NF-кB, enhanced neuroplasticity signaling of CaMKII-mTOR-BDNF, and attenuated the upregulated expressions of the NMDAR sub-units GluN1 and GluN2B in the hippocampus of LPS-treated mice. GMA, JWX and Scop rapidly restored the number of BDNF-positive cells reduced by LPS treatment in the CA3 region of the hippocampus
T2  - Journal of Ethnopharmacology
T1  - A refined formula derived from Jiawei-Xiaoyao pill exerts rapid antidepressant-like effects in LPS-induced depression by reducing neuroinflammation and restoring neuroplasticity signaling
VL  - 335
SP  - 118647
DO  - 10.1016/j.jep.2024.118647
ER  - 

@article{
author = "Wu, Zhangjie and Yin, Ying and Liu, Ruiyi and Li, Xianhui and Sun, Yan and Yau, Suk-yu and Wu, Lei and Liu, Yan and Adžić, Miroslav and Zhang, Hailou and Chen, Gang",
year = "2024",
abstract = "Ethnopharmacological relevance: Jiawei-Xiaoyao Pill (JWX), a classic formula in traditional Chinese medicine, is derived from Xiaoyao Pill by adding significant amounts of Gardeniae Fructus (GF) and Moutan Cortex (MC). It is frequently used for the treatment of depression. JWX has been demonstrated to uniquely elicit rapid antidepressant-like effects within the prescribed dosage range. To date, GF has been shown to have rapid antidepressant-like effects, but a much higher dose is required than its proportion in JWX. It is assumed that the synergism of GF with a minimum number of other herbs in JWX serves as a refined formula that exerts these rapid antidepressant-like effects. Identification of a refined formula is important for prioritizing the herbs and ingredients to optimize the quality control of JWX. However, such a refined formula for JWX has not been identified yet. Aim of the study: Here we aimed to identify a refined formula derived from JWX for optimized rapid antidepressant-like effects. Since the neuroinflammation mechanism involving in depression treatment has not been previously investigated for JWX, we tested the mechanism for both JWX and the refined formula. Materials and methods: Individual herbs (MC; ASR, Angelica Sinensis Radix; Bupleuri Radix; Paeonia Radix Alba) that show antidepressant-like responses were mixed with GF at the proportional dosage in JWX to identify the refined formula. Rapid antidepressant-like effects were assessed by using NSF (Novelty Suppressed Feeding Test) and other behavioral tests following a single administration. The identified formula was further tested in a lipopolysaccharide (LPS)-induced depressive model, and the molecular signaling mechanisms were investigated using Western blot analysis, immunofluorescence, and pharmacological inhibition of mTOR signaling. Scopolamine (Scop) was used as a positive control for induction of rapid antidepressant effects. Results: A combination of GF, MC and ASR (GMA) at their dosages proportional to JWX induced behavioral signs of rapid antidepressant-like responses in both normal and LPS-treated mice, with the antidepressant-like effects sustained for 5 d. Similar to JWX or Scop, GMA rapidly reduced the neuroinflammation signaling of Iba-1-NF-кB, enhanced neuroplasticity signaling of CaMKII-mTOR-BDNF, and attenuated the upregulated expressions of the NMDAR sub-units GluN1 and GluN2B in the hippocampus of LPS-treated mice. GMA, JWX and Scop rapidly restored the number of BDNF-positive cells reduced by LPS treatment in the CA3 region of the hippocampus",
journal = "Journal of Ethnopharmacology",
title = "A refined formula derived from Jiawei-Xiaoyao pill exerts rapid antidepressant-like effects in LPS-induced depression by reducing neuroinflammation and restoring neuroplasticity signaling",
volume = "335",
pages = "118647",
doi = "10.1016/j.jep.2024.118647"
}

Wu, Z., Yin, Y., Liu, R., Li, X., Sun, Y., Yau, S., Wu, L., Liu, Y., Adžić, M., Zhang, H.,& Chen, G.. (2024). A refined formula derived from Jiawei-Xiaoyao pill exerts rapid antidepressant-like effects in LPS-induced depression by reducing neuroinflammation and restoring neuroplasticity signaling. in Journal of Ethnopharmacology, 335, 118647.
https://doi.org/10.1016/j.jep.2024.118647

Wu Z, Yin Y, Liu R, Li X, Sun Y, Yau S, Wu L, Liu Y, Adžić M, Zhang H, Chen G. A refined formula derived from Jiawei-Xiaoyao pill exerts rapid antidepressant-like effects in LPS-induced depression by reducing neuroinflammation and restoring neuroplasticity signaling. in Journal of Ethnopharmacology. 2024;335:118647.
doi:10.1016/j.jep.2024.118647 .

Wu, Zhangjie, Yin, Ying, Liu, Ruiyi, Li, Xianhui, Sun, Yan, Yau, Suk-yu, Wu, Lei, Liu, Yan, Adžić, Miroslav, Zhang, Hailou, Chen, Gang, "A refined formula derived from Jiawei-Xiaoyao pill exerts rapid antidepressant-like effects in LPS-induced depression by reducing neuroinflammation and restoring neuroplasticity signaling" in Journal of Ethnopharmacology, 335 (2024):118647,
https://doi.org/10.1016/j.jep.2024.118647 . .

TY  - JOUR
AU  - Yim, Chi Ming
AU  - Siemann, Gesa-R.
AU  - Stavrić, Srđan
AU  - Khim, Seunghyun
AU  - Benedičič, Izidor
AU  - Murgatroyd, Philip A. E.
AU  - Antonelli, Tommaso
AU  - Watson, Matthew D.
AU  - Mackenzie, Andrew P.
AU  - Picozzi, Silvia
AU  - King, Phil D. C.
AU  - Wahl, Peter
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/13743
T2  - Nature Communications
T1  - Avoided metallicity in a hole-doped Mott insulator on a triangular lattice
VL  - 15
DO  - 10.1038/s41467-024-52007-z
ER  - 

@article{
author = "Yim, Chi Ming and Siemann, Gesa-R. and Stavrić, Srđan and Khim, Seunghyun and Benedičič, Izidor and Murgatroyd, Philip A. E. and Antonelli, Tommaso and Watson, Matthew D. and Mackenzie, Andrew P. and Picozzi, Silvia and King, Phil D. C. and Wahl, Peter",
year = "2024",
journal = "Nature Communications",
title = "Avoided metallicity in a hole-doped Mott insulator on a triangular lattice",
volume = "15",
doi = "10.1038/s41467-024-52007-z"
}

Yim, C. M., Siemann, Gesa-R., Stavrić, S., Khim, S., Benedičič, I., Murgatroyd, P. A. E., Antonelli, T., Watson, M. D., Mackenzie, A. P., Picozzi, S., King, P. D. C.,& Wahl, P.. (2024). Avoided metallicity in a hole-doped Mott insulator on a triangular lattice. in Nature Communications, 15.
https://doi.org/10.1038/s41467-024-52007-z

Yim CM, Siemann G, Stavrić S, Khim S, Benedičič I, Murgatroyd PAE, Antonelli T, Watson MD, Mackenzie AP, Picozzi S, King PDC, Wahl P. Avoided metallicity in a hole-doped Mott insulator on a triangular lattice. in Nature Communications. 2024;15.
doi:10.1038/s41467-024-52007-z .

Yim, Chi Ming, Siemann, Gesa-R., Stavrić, Srđan, Khim, Seunghyun, Benedičič, Izidor, Murgatroyd, Philip A. E., Antonelli, Tommaso, Watson, Matthew D., Mackenzie, Andrew P., Picozzi, Silvia, King, Phil D. C., Wahl, Peter, "Avoided metallicity in a hole-doped Mott insulator on a triangular lattice" in Nature Communications, 15 (2024),
https://doi.org/10.1038/s41467-024-52007-z . .

TY  - JOUR
AU  - Brdarić, Tanja
AU  - Aćimović, Danka
AU  - Švorc, Lubomir
AU  - Vasić Anićijević, Dragana D.
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/13716
AB  - Electrochemical advanced oxidation processes (EAOPs) are at the forefront of scientific research as green technologies aimed at effectively purifying polluted aquatic environments. These methods utilize electrochemical processes to generate reactive oxygen species (ROS), such as the hydroxyl radical (•OH), either on the anode surface or within the bulk solution, which can partially degrade or completely mineralize organic pollutants. The aim of the article is to provide a bibliometric analysis of research articles specifically focused on the application and development of EAOPs in wastewater treatment over the past five years. Utilizing the most extensive database for literature searches, Web of Science Core Collection (WoS), which encompasses 95% of global publications, a total of 649 research articles were retrieved by limiting the search results to words associated with EAOPs in titles, keywords, and abstracts. The bibliometric dataset was then processed using CiteSpace and VOSviewer software. The People’s Republic of China is emerging as the country with the highest production in the field, demonstrating a strong commitment to research and a leading role in international cooperation. This leadership is evident through China’s substantial contributions to the body of literature and its extensive network of collaborations with researchers worldwide. Meanwhile, Australia, despite producing fewer publications, has achieved a high citation rate, underscoring the significant impact and influence of its research within the scientific community. One of the most promising and extensively studied topics in this field is the electro-Fenton process, which has garnered considerable attention due to its potential applications and remarkable efficiency in various contexts. The bibliometric analysis conducted in this study allowed for a detailed visualization of the currently available literature data and corresponding developing trends. By mapping out the key areas of focus, prominent researchers, influential journals, and collaborative networks, this analysis provides valuable insights. These insights can facilitate future joint research endeavors, enhance collaboration, and promote the sharing of knowledge and best practices among researchers globally.
T2  - Coatings
T1  - Bibliometric Study of Electrochemical Advanced Oxidation Processes (EAOPs) for Wastewater Treatment
VL  - 14
IS  - 8
SP  - 1060
DO  - 10.3390/coatings14081060
ER  - 

@article{
author = "Brdarić, Tanja and Aćimović, Danka and Švorc, Lubomir and Vasić Anićijević, Dragana D.",
year = "2024",
abstract = "Electrochemical advanced oxidation processes (EAOPs) are at the forefront of scientific research as green technologies aimed at effectively purifying polluted aquatic environments. These methods utilize electrochemical processes to generate reactive oxygen species (ROS), such as the hydroxyl radical (•OH), either on the anode surface or within the bulk solution, which can partially degrade or completely mineralize organic pollutants. The aim of the article is to provide a bibliometric analysis of research articles specifically focused on the application and development of EAOPs in wastewater treatment over the past five years. Utilizing the most extensive database for literature searches, Web of Science Core Collection (WoS), which encompasses 95% of global publications, a total of 649 research articles were retrieved by limiting the search results to words associated with EAOPs in titles, keywords, and abstracts. The bibliometric dataset was then processed using CiteSpace and VOSviewer software. The People’s Republic of China is emerging as the country with the highest production in the field, demonstrating a strong commitment to research and a leading role in international cooperation. This leadership is evident through China’s substantial contributions to the body of literature and its extensive network of collaborations with researchers worldwide. Meanwhile, Australia, despite producing fewer publications, has achieved a high citation rate, underscoring the significant impact and influence of its research within the scientific community. One of the most promising and extensively studied topics in this field is the electro-Fenton process, which has garnered considerable attention due to its potential applications and remarkable efficiency in various contexts. The bibliometric analysis conducted in this study allowed for a detailed visualization of the currently available literature data and corresponding developing trends. By mapping out the key areas of focus, prominent researchers, influential journals, and collaborative networks, this analysis provides valuable insights. These insights can facilitate future joint research endeavors, enhance collaboration, and promote the sharing of knowledge and best practices among researchers globally.",
journal = "Coatings",
title = "Bibliometric Study of Electrochemical Advanced Oxidation Processes (EAOPs) for Wastewater Treatment",
volume = "14",
number = "8",
pages = "1060",
doi = "10.3390/coatings14081060"
}

Brdarić, T., Aćimović, D., Švorc, L.,& Vasić Anićijević, D. D.. (2024). Bibliometric Study of Electrochemical Advanced Oxidation Processes (EAOPs) for Wastewater Treatment. in Coatings, 14(8), 1060.
https://doi.org/10.3390/coatings14081060

Brdarić T, Aćimović D, Švorc L, Vasić Anićijević DD. Bibliometric Study of Electrochemical Advanced Oxidation Processes (EAOPs) for Wastewater Treatment. in Coatings. 2024;14(8):1060.
doi:10.3390/coatings14081060 .

Brdarić, Tanja, Aćimović, Danka, Švorc, Lubomir, Vasić Anićijević, Dragana D., "Bibliometric Study of Electrochemical Advanced Oxidation Processes (EAOPs) for Wastewater Treatment" in Coatings, 14, no. 8 (2024):1060,
https://doi.org/10.3390/coatings14081060 . .

TY  - JOUR
AU  - Topalović, Dušan
AU  - Tasić, Viša
AU  - Stanković Petrović, Jelena
AU  - Vlahović, Jelena
AU  - Radenković, Mirjana
AU  - Smičiklas, Ivana
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/13741
AB  - Although low-cost air quality sensors facilitate the implementation of denser air quality monitoring networks, enabling a more realistic assessment of individual exposure to airborne pollutants, their sensitivity to multifaceted field conditions is often overlooked in laboratory testing. This gap was addressed by introducing an in-field calibration and validation of three PAQMON 1.0 mobile sensing low-cost platforms developed at the Mining and Metallurgy Institute in Bor, Republic of Serbia. A configuration tailored for monitoring PM2.5 and PM10 mass concentrations along with meteorological parameters was employed for outdoor measurement campaigns in Bor, spanning heating (HS) and non-heating (NHS) seasons. A statistically significant positive linear correlation between raw PM2.5 and PM10 measurements during both campaigns (R > 0.90, p ≤ 0.001) was observed. Measurements obtained from the uncalibrated NOVA SDS011 sensors integrated into the PAQMON 1.0 platforms exhibited a substantial and statistically significant correlation with the GRIMM EDM180 monitor (R > 0.60, p ≤ 0.001). The calibration models based on linear and Random Forest (RF) regression were compared. RF models provided more accurate descriptions of air quality, with average adjR2 values for air quality variables in the range of 0.70 to 0.80 and average NRMSE values between 0.35 and 0.77. RF-calibrated PAQMON 1.0 platforms displayed divergent levels of accuracy across different pollutant concentration ranges, achieving a data quality objective of 50% during both measurement campaigns. For PM2.5, uncertainty (Ur) was below 50% for concentrations between 9.06 and 34.99 μg/m3 in HS and 5.75 and 17.58 μg/m3 in NHS, while for PM10, it stayed below 50% from 19.11 to 51.13 μg/m3 in HS and 11.72 to 38.86 μg/m3 in NHS.
T2  - Environmental Monitoring and Assessment
T1  - Unveiling the potential of a novel portable air quality platform for assessment of fine and coarse particulate matter: in-field testing, calibration, and machine learning insights
VL  - 196
IS  - 196
DO  - 10.1007/s10661-024-13069-0
ER  - 

@article{
author = "Topalović, Dušan and Tasić, Viša and Stanković Petrović, Jelena and Vlahović, Jelena and Radenković, Mirjana and Smičiklas, Ivana",
year = "2024",
abstract = "Although low-cost air quality sensors facilitate the implementation of denser air quality monitoring networks, enabling a more realistic assessment of individual exposure to airborne pollutants, their sensitivity to multifaceted field conditions is often overlooked in laboratory testing. This gap was addressed by introducing an in-field calibration and validation of three PAQMON 1.0 mobile sensing low-cost platforms developed at the Mining and Metallurgy Institute in Bor, Republic of Serbia. A configuration tailored for monitoring PM2.5 and PM10 mass concentrations along with meteorological parameters was employed for outdoor measurement campaigns in Bor, spanning heating (HS) and non-heating (NHS) seasons. A statistically significant positive linear correlation between raw PM2.5 and PM10 measurements during both campaigns (R > 0.90, p ≤ 0.001) was observed. Measurements obtained from the uncalibrated NOVA SDS011 sensors integrated into the PAQMON 1.0 platforms exhibited a substantial and statistically significant correlation with the GRIMM EDM180 monitor (R > 0.60, p ≤ 0.001). The calibration models based on linear and Random Forest (RF) regression were compared. RF models provided more accurate descriptions of air quality, with average adjR2 values for air quality variables in the range of 0.70 to 0.80 and average NRMSE values between 0.35 and 0.77. RF-calibrated PAQMON 1.0 platforms displayed divergent levels of accuracy across different pollutant concentration ranges, achieving a data quality objective of 50% during both measurement campaigns. For PM2.5, uncertainty (Ur) was below 50% for concentrations between 9.06 and 34.99 μg/m3 in HS and 5.75 and 17.58 μg/m3 in NHS, while for PM10, it stayed below 50% from 19.11 to 51.13 μg/m3 in HS and 11.72 to 38.86 μg/m3 in NHS.",
journal = "Environmental Monitoring and Assessment",
title = "Unveiling the potential of a novel portable air quality platform for assessment of fine and coarse particulate matter: in-field testing, calibration, and machine learning insights",
volume = "196",
number = "196",
doi = "10.1007/s10661-024-13069-0"
}

Topalović, D., Tasić, V., Stanković Petrović, J., Vlahović, J., Radenković, M.,& Smičiklas, I.. (2024). Unveiling the potential of a novel portable air quality platform for assessment of fine and coarse particulate matter: in-field testing, calibration, and machine learning insights. in Environmental Monitoring and Assessment, 196(196).
https://doi.org/10.1007/s10661-024-13069-0

Topalović D, Tasić V, Stanković Petrović J, Vlahović J, Radenković M, Smičiklas I. Unveiling the potential of a novel portable air quality platform for assessment of fine and coarse particulate matter: in-field testing, calibration, and machine learning insights. in Environmental Monitoring and Assessment. 2024;196(196).
doi:10.1007/s10661-024-13069-0 .

Topalović, Dušan, Tasić, Viša, Stanković Petrović, Jelena, Vlahović, Jelena, Radenković, Mirjana, Smičiklas, Ivana, "Unveiling the potential of a novel portable air quality platform for assessment of fine and coarse particulate matter: in-field testing, calibration, and machine learning insights" in Environmental Monitoring and Assessment, 196, no. 196 (2024),
https://doi.org/10.1007/s10661-024-13069-0 . .