TY  - CONF
AU  - Čolović, Mirjana
AU  - Korićanac, Lela
AU  - Žakula, Jelena
AU  - Savić, Nada
AU  - Parac-Vogt, Tatjana
AU  - Krstić, Danijela
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12944
AB  - The aim of this study was to in vitro assess the anti-tumor potential of Fe(III)-substituted monolacunary Wells-Dawson polyoxotungstate, K7[FeIII(α2-P2W17O61)(H2O)] (FeWD) against human melanoma A375 cells. A375 cells were treated in vitro with FeWD in the concentration range of 0.001-1 mM, for 24, 48, and 72 hours. FeWD decreased A375 cell viability in a dose- and time-dependent manner. IC50 values (in mM), as a marker of the cytotoxic potency of FeWD, were obtained as follows: 1, 0.58, and 0.51, for 24-, 48-, and 72-hour exposure, respectively. However, in comparison with cisplatin as a gold standard in cancer chemotherapy, which was used as a positive control, IC50 values (in mM) were significantly higher than those obtained for cisplatin (0.09, 0.07, and 0.043, for 24, 48, and 72 hours, respectively). For this reason, the studied FeWD polyoxometalate could not be considered a superior anti-cancer candidate compared to the standard chemotherapeutic.
C3  - International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings
T1  - Anti-human melanoma effect of Fe(III)-containing wells-dawson nanocluster in vitro
VL  - 2
SP  - 24
EP  - 27
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12944
ER  - 

@conference{
author = "Čolović, Mirjana and Korićanac, Lela and Žakula, Jelena and Savić, Nada and Parac-Vogt, Tatjana and Krstić, Danijela",
year = "2024",
abstract = "The aim of this study was to in vitro assess the anti-tumor potential of Fe(III)-substituted monolacunary Wells-Dawson polyoxotungstate, K7[FeIII(α2-P2W17O61)(H2O)] (FeWD) against human melanoma A375 cells. A375 cells were treated in vitro with FeWD in the concentration range of 0.001-1 mM, for 24, 48, and 72 hours. FeWD decreased A375 cell viability in a dose- and time-dependent manner. IC50 values (in mM), as a marker of the cytotoxic potency of FeWD, were obtained as follows: 1, 0.58, and 0.51, for 24-, 48-, and 72-hour exposure, respectively. However, in comparison with cisplatin as a gold standard in cancer chemotherapy, which was used as a positive control, IC50 values (in mM) were significantly higher than those obtained for cisplatin (0.09, 0.07, and 0.043, for 24, 48, and 72 hours, respectively). For this reason, the studied FeWD polyoxometalate could not be considered a superior anti-cancer candidate compared to the standard chemotherapeutic.",
journal = "International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings",
title = "Anti-human melanoma effect of Fe(III)-containing wells-dawson nanocluster in vitro",
volume = "2",
pages = "24-27",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12944"
}

Čolović, M., Korićanac, L., Žakula, J., Savić, N., Parac-Vogt, T.,& Krstić, D.. (2024). Anti-human melanoma effect of Fe(III)-containing wells-dawson nanocluster in vitro. in International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings, 2, 24-27.
https://hdl.handle.net/21.15107/rcub_vinar_12944

Čolović M, Korićanac L, Žakula J, Savić N, Parac-Vogt T, Krstić D. Anti-human melanoma effect of Fe(III)-containing wells-dawson nanocluster in vitro. in International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings. 2024;2:24-27.
https://hdl.handle.net/21.15107/rcub_vinar_12944 .

Čolović, Mirjana, Korićanac, Lela, Žakula, Jelena, Savić, Nada, Parac-Vogt, Tatjana, Krstić, Danijela, "Anti-human melanoma effect of Fe(III)-containing wells-dawson nanocluster in vitro" in International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings, 2 (2024):24-27,
https://hdl.handle.net/21.15107/rcub_vinar_12944 .

TY  - CONF
AU  - Krstić, Danijela
AU  - Lalatović, Jovana
AU  - Mrđa, Davor
AU  - Stojanović, Marko
AU  - Savić, Nada
AU  - Parac-Vogt, Tatjana
AU  - Čolović, Mirjana
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12945
AB  - The purpose of this study was to evaluate in vitro contrast properties of a synthesized Wells-Dawson P2W17O61)2]·19H2O (Hf-WD 1:2), as a potential contrast agent for computed tomography (CT). X-ray attenuation was determined in vitro in the presence of increasing tungsten concentrations (3.125-100 mM) of Hf-WD 1:2. In order to compare the contrast properties of the tungsten-containing Hf-WD 1:2 with a commercially available CT contrast agent that has been used in clinical practice, X-ray attenuation was presented for the same iodine concentrations of iodine-based iohexol solution as well. Higher HU values for particular concentrations were obtained for Hf-WD 1:2 in comparison with those determined for the standard iohexol. Thus, the studied Hf-WD 1:2 POM could be considered a promising contrast agent candidate for CT. Nevertheless, further development of Hf-WD 1:2 as a potential CT contrast requires additional CT studies in vivo and relevant toxicity studies in vitro and in vivo as well.
C3  - International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings
T1  - Hafnium-containing Wells-Dawson nanocluster as a promising contrast agent candidate
VL  - 2
SP  - 39
EP  - 42
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12945
ER  - 

@conference{
author = "Krstić, Danijela and Lalatović, Jovana and Mrđa, Davor and Stojanović, Marko and Savić, Nada and Parac-Vogt, Tatjana and Čolović, Mirjana",
year = "2024",
abstract = "The purpose of this study was to evaluate in vitro contrast properties of a synthesized Wells-Dawson P2W17O61)2]·19H2O (Hf-WD 1:2), as a potential contrast agent for computed tomography (CT). X-ray attenuation was determined in vitro in the presence of increasing tungsten concentrations (3.125-100 mM) of Hf-WD 1:2. In order to compare the contrast properties of the tungsten-containing Hf-WD 1:2 with a commercially available CT contrast agent that has been used in clinical practice, X-ray attenuation was presented for the same iodine concentrations of iodine-based iohexol solution as well. Higher HU values for particular concentrations were obtained for Hf-WD 1:2 in comparison with those determined for the standard iohexol. Thus, the studied Hf-WD 1:2 POM could be considered a promising contrast agent candidate for CT. Nevertheless, further development of Hf-WD 1:2 as a potential CT contrast requires additional CT studies in vivo and relevant toxicity studies in vitro and in vivo as well.",
journal = "International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings",
title = "Hafnium-containing Wells-Dawson nanocluster as a promising contrast agent candidate",
volume = "2",
pages = "39-42",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12945"
}

Krstić, D., Lalatović, J., Mrđa, D., Stojanović, M., Savić, N., Parac-Vogt, T.,& Čolović, M.. (2024). Hafnium-containing Wells-Dawson nanocluster as a promising contrast agent candidate. in International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings, 2, 39-42.
https://hdl.handle.net/21.15107/rcub_vinar_12945

Krstić D, Lalatović J, Mrđa D, Stojanović M, Savić N, Parac-Vogt T, Čolović M. Hafnium-containing Wells-Dawson nanocluster as a promising contrast agent candidate. in International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings. 2024;2:39-42.
https://hdl.handle.net/21.15107/rcub_vinar_12945 .

Krstić, Danijela, Lalatović, Jovana, Mrđa, Davor, Stojanović, Marko, Savić, Nada, Parac-Vogt, Tatjana, Čolović, Mirjana, "Hafnium-containing Wells-Dawson nanocluster as a promising contrast agent candidate" in International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings, 2 (2024):39-42,
https://hdl.handle.net/21.15107/rcub_vinar_12945 .

TY  - CONF
AU  - Lalatović, Jovana
AU  - Čolović, Mirjana
AU  - Mrđa, Davor
AU  - Stojanović, Marko
AU  - Krstić, Danijela
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12946
AB  - In this study contrast properties for computed tomography (CT) of two tungstate-containing molecules differing in size, shape, and structure: Keggin type polyoxometalate, 12-tungstosilicic acid, WSiA and sodium tungstate, Na2WO4, were assessed in vitro. In this aim, X-ray attenuation was monitored in vitro at different tungsten concentrations in the range of 3.125-100 mM. A stronger X-ray attenuation was observed for Na2WO4 in the presence of the same tungsten concentrations. In addition, both Na2WO4 and WSiA demonstrated better contrast performance compared to iodine-based iohexol solution, which has been widely applied as a contrast agent for CT. Accordingly, tungsten-containing compounds deserve attention as promising new-generation CT contrast candidates. Thus, future studies should be directed to the synthesis of novel tungsten molecules of different structures resulting in appropriate contrast and low toxicity.
C3  - International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings
T1  - Tungsten-based molecules of different structure as potential contrast agents
VL  - 2
SP  - 43
EP  - 46
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12946
ER  - 

@conference{
author = "Lalatović, Jovana and Čolović, Mirjana and Mrđa, Davor and Stojanović, Marko and Krstić, Danijela",
year = "2024",
abstract = "In this study contrast properties for computed tomography (CT) of two tungstate-containing molecules differing in size, shape, and structure: Keggin type polyoxometalate, 12-tungstosilicic acid, WSiA and sodium tungstate, Na2WO4, were assessed in vitro. In this aim, X-ray attenuation was monitored in vitro at different tungsten concentrations in the range of 3.125-100 mM. A stronger X-ray attenuation was observed for Na2WO4 in the presence of the same tungsten concentrations. In addition, both Na2WO4 and WSiA demonstrated better contrast performance compared to iodine-based iohexol solution, which has been widely applied as a contrast agent for CT. Accordingly, tungsten-containing compounds deserve attention as promising new-generation CT contrast candidates. Thus, future studies should be directed to the synthesis of novel tungsten molecules of different structures resulting in appropriate contrast and low toxicity.",
journal = "International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings",
title = "Tungsten-based molecules of different structure as potential contrast agents",
volume = "2",
pages = "43-46",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12946"
}

Lalatović, J., Čolović, M., Mrđa, D., Stojanović, M.,& Krstić, D.. (2024). Tungsten-based molecules of different structure as potential contrast agents. in International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings, 2, 43-46.
https://hdl.handle.net/21.15107/rcub_vinar_12946

Lalatović J, Čolović M, Mrđa D, Stojanović M, Krstić D. Tungsten-based molecules of different structure as potential contrast agents. in International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings. 2024;2:43-46.
https://hdl.handle.net/21.15107/rcub_vinar_12946 .

Lalatović, Jovana, Čolović, Mirjana, Mrđa, Davor, Stojanović, Marko, Krstić, Danijela, "Tungsten-based molecules of different structure as potential contrast agents" in International Multidisciplinary Conference "Challenges of Contemporary Higher Education" - CCHE 2024 : Book of proceedings, 2 (2024):43-46,
https://hdl.handle.net/21.15107/rcub_vinar_12946 .

TY  - JOUR
AU  - Stojanović, Marko
AU  - Čolović, Mirjana B.
AU  - Lalatović, Jovana
AU  - Milosavljević, Aleksandra
AU  - Savić, Nada D.
AU  - Declerck, Kilian
AU  - Radosavljević, Branimir
AU  - Ćetković, Mila
AU  - Kravić-Stevović, Tamara
AU  - Parac-Vogt, Tatjana N.
AU  - Krstić, Danijela
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12867
AB  - Polyoxotungstate nanoclusters have recently emerged as promising contrast agents for computed tomography (CT). In order to evaluate their clinical potential, in this study, we evaluated the in vitro CT imaging properties, potential toxic effects in vivo, and tissue distribution of monolacunary Wells–Dawson polyoxometalate, α2-K10P2W17O61.20H2O (mono-WD POM). Mono-WD POM showed superior X-ray attenuation compared to other tungsten-containing nanoclusters (its parent WD-POM and Keggin POM) and the standard iodine-based contrast agent (iohexol). The calculated X-ray attenuation linear slope for mono-WD POM was significantly higher compared to parent WD-POM, Keggin POM, and iohexol (5.97 ± 0.14 vs. 4.84 ± 0.05, 4.55 ± 0.16, and 4.30 ± 0.09, respectively). Acute oral (maximum-administered dose (MAD) = 960 mg/kg) and intravenous administration (1/10, 1/5, and 1/3 MAD) of mono-WD POM did not induce unexpected changes in rats’ general habits or mortality. Results of blood gas analysis, CO-oximetry status, and the levels of electrolytes, glucose, lactate, creatinine, and BUN demonstrated a dose-dependent tendency 14 days after intravenous administration of mono-WD POM. The most significant differences compared to the control were observed for 1/3 MAD, being approximately seventy times higher than the typically used dose (0.015 mmol W/kg) of tungsten-based contrast agents. The highest tungsten deposition was found in the kidney (1/3 MAD—0.67 ± 0.12; 1/5 MAD—0.59 ± 0.07; 1/10 MAD—0.54 ± 0.05), which corresponded to detected morphological irregularities, electrolyte imbalance, and increased BUN levels.
T2  - International Journal of Molecular Sciences
T1  - Monolacunary Wells-Dawson Polyoxometalate as a Novel Contrast Agent for Computed Tomography: A Comprehensive Study on In Vivo Toxicity and Biodistribution
VL  - 25
IS  - 5
SP  - 2569
DO  - 10.3390/ijms25052569
ER  - 

@article{
author = "Stojanović, Marko and Čolović, Mirjana B. and Lalatović, Jovana and Milosavljević, Aleksandra and Savić, Nada D. and Declerck, Kilian and Radosavljević, Branimir and Ćetković, Mila and Kravić-Stevović, Tamara and Parac-Vogt, Tatjana N. and Krstić, Danijela",
year = "2024",
abstract = "Polyoxotungstate nanoclusters have recently emerged as promising contrast agents for computed tomography (CT). In order to evaluate their clinical potential, in this study, we evaluated the in vitro CT imaging properties, potential toxic effects in vivo, and tissue distribution of monolacunary Wells–Dawson polyoxometalate, α2-K10P2W17O61.20H2O (mono-WD POM). Mono-WD POM showed superior X-ray attenuation compared to other tungsten-containing nanoclusters (its parent WD-POM and Keggin POM) and the standard iodine-based contrast agent (iohexol). The calculated X-ray attenuation linear slope for mono-WD POM was significantly higher compared to parent WD-POM, Keggin POM, and iohexol (5.97 ± 0.14 vs. 4.84 ± 0.05, 4.55 ± 0.16, and 4.30 ± 0.09, respectively). Acute oral (maximum-administered dose (MAD) = 960 mg/kg) and intravenous administration (1/10, 1/5, and 1/3 MAD) of mono-WD POM did not induce unexpected changes in rats’ general habits or mortality. Results of blood gas analysis, CO-oximetry status, and the levels of electrolytes, glucose, lactate, creatinine, and BUN demonstrated a dose-dependent tendency 14 days after intravenous administration of mono-WD POM. The most significant differences compared to the control were observed for 1/3 MAD, being approximately seventy times higher than the typically used dose (0.015 mmol W/kg) of tungsten-based contrast agents. The highest tungsten deposition was found in the kidney (1/3 MAD—0.67 ± 0.12; 1/5 MAD—0.59 ± 0.07; 1/10 MAD—0.54 ± 0.05), which corresponded to detected morphological irregularities, electrolyte imbalance, and increased BUN levels.",
journal = "International Journal of Molecular Sciences",
title = "Monolacunary Wells-Dawson Polyoxometalate as a Novel Contrast Agent for Computed Tomography: A Comprehensive Study on In Vivo Toxicity and Biodistribution",
volume = "25",
number = "5",
pages = "2569",
doi = "10.3390/ijms25052569"
}

Stojanović, M., Čolović, M. B., Lalatović, J., Milosavljević, A., Savić, N. D., Declerck, K., Radosavljević, B., Ćetković, M., Kravić-Stevović, T., Parac-Vogt, T. N.,& Krstić, D.. (2024). Monolacunary Wells-Dawson Polyoxometalate as a Novel Contrast Agent for Computed Tomography: A Comprehensive Study on In Vivo Toxicity and Biodistribution. in International Journal of Molecular Sciences, 25(5), 2569.
https://doi.org/10.3390/ijms25052569

Stojanović M, Čolović MB, Lalatović J, Milosavljević A, Savić ND, Declerck K, Radosavljević B, Ćetković M, Kravić-Stevović T, Parac-Vogt TN, Krstić D. Monolacunary Wells-Dawson Polyoxometalate as a Novel Contrast Agent for Computed Tomography: A Comprehensive Study on In Vivo Toxicity and Biodistribution. in International Journal of Molecular Sciences. 2024;25(5):2569.
doi:10.3390/ijms25052569 .

Stojanović, Marko, Čolović, Mirjana B., Lalatović, Jovana, Milosavljević, Aleksandra, Savić, Nada D., Declerck, Kilian, Radosavljević, Branimir, Ćetković, Mila, Kravić-Stevović, Tamara, Parac-Vogt, Tatjana N., Krstić, Danijela, "Monolacunary Wells-Dawson Polyoxometalate as a Novel Contrast Agent for Computed Tomography: A Comprehensive Study on In Vivo Toxicity and Biodistribution" in International Journal of Molecular Sciences, 25, no. 5 (2024):2569,
https://doi.org/10.3390/ijms25052569 . .

TY  - CONF
AU  - Čolović, Mirjana
AU  - Žakula, Jelena
AU  - Korićanac, Lela
AU  - Savić, Nada
AU  - Parac-Vogt, Tatjana
AU  - Krstić, Danijela Z.
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12927
AB  - The aim of this study was to assess in vitro cytotoxic activity of a monolacunary Wells- Dawson nanocluster, α2-K10P2W17O61.20H2O (lacunary WD) against cervical carcinoma HeLa cells  as a commonly used model system for the evaluation of antitumor properties. After HeLa cells had been exposed to the investigated polyoxotungstate (the concentration range of 0.001 - 1 mM) for 24, 48, and 72 h, relative cell viability (expressed as a percentage of control) was determined.  The obtained results showed that lacunary WD affected HeLa cell viability in a concentration- and time-dependent manner. IC50 values (in μM), calculated using sigmoidal fitting experimental  plots, were as follows: 24.11 ± 9.95, 12.74 ± 0.096, and 11.48 ± 0.12 for 24, 48, and 72 hours treatment, respectively. In comparison with cisplatin, (positive control), IC50 values (μM) for 24 hours treatment were similar – 24.11 (lacunary WD) vs. 24.49 (cisplatin). However, after 48 and 72 hours IC50 obtained for cisplatin were found to be lower – 8.81 and 4.93 μM, respectively. Accordingly, the studied WD polyoxotungstate could not be regarded as a superior anticancer agent in comparison with the standard chemotherapeutic. Nevertheless, this studied nanocluster deserves attention as a promising antitumor therapeutic and as a good platform for the design of next-generation metal-based anticancer agents.
PB  - Kragujevac : Institute for Information Technologies, University of Kragujevac
C3  - ICCBIKG 2023 : 2nd International Conference on Chemo and Bioinformatics : Book of Proceedings
T1  - In vitro cytotoxic activity of a monolacunary Wells-Dawson nanocluster against cervical carcinoma HeLa cells
SP  - 415
EP  - 418
DO  - 10.46793/ICCBI23.415C
ER  - 

@conference{
author = "Čolović, Mirjana and Žakula, Jelena and Korićanac, Lela and Savić, Nada and Parac-Vogt, Tatjana and Krstić, Danijela Z.",
year = "2023",
abstract = "The aim of this study was to assess in vitro cytotoxic activity of a monolacunary Wells- Dawson nanocluster, α2-K10P2W17O61.20H2O (lacunary WD) against cervical carcinoma HeLa cells  as a commonly used model system for the evaluation of antitumor properties. After HeLa cells had been exposed to the investigated polyoxotungstate (the concentration range of 0.001 - 1 mM) for 24, 48, and 72 h, relative cell viability (expressed as a percentage of control) was determined.  The obtained results showed that lacunary WD affected HeLa cell viability in a concentration- and time-dependent manner. IC50 values (in μM), calculated using sigmoidal fitting experimental  plots, were as follows: 24.11 ± 9.95, 12.74 ± 0.096, and 11.48 ± 0.12 for 24, 48, and 72 hours treatment, respectively. In comparison with cisplatin, (positive control), IC50 values (μM) for 24 hours treatment were similar – 24.11 (lacunary WD) vs. 24.49 (cisplatin). However, after 48 and 72 hours IC50 obtained for cisplatin were found to be lower – 8.81 and 4.93 μM, respectively. Accordingly, the studied WD polyoxotungstate could not be regarded as a superior anticancer agent in comparison with the standard chemotherapeutic. Nevertheless, this studied nanocluster deserves attention as a promising antitumor therapeutic and as a good platform for the design of next-generation metal-based anticancer agents.",
publisher = "Kragujevac : Institute for Information Technologies, University of Kragujevac",
journal = "ICCBIKG 2023 : 2nd International Conference on Chemo and Bioinformatics : Book of Proceedings",
title = "In vitro cytotoxic activity of a monolacunary Wells-Dawson nanocluster against cervical carcinoma HeLa cells",
pages = "415-418",
doi = "10.46793/ICCBI23.415C"
}

Čolović, M., Žakula, J., Korićanac, L., Savić, N., Parac-Vogt, T.,& Krstić, D. Z.. (2023). In vitro cytotoxic activity of a monolacunary Wells-Dawson nanocluster against cervical carcinoma HeLa cells. in ICCBIKG 2023 : 2nd International Conference on Chemo and Bioinformatics : Book of Proceedings
Kragujevac : Institute for Information Technologies, University of Kragujevac., 415-418.
https://doi.org/10.46793/ICCBI23.415C

Čolović M, Žakula J, Korićanac L, Savić N, Parac-Vogt T, Krstić DZ. In vitro cytotoxic activity of a monolacunary Wells-Dawson nanocluster against cervical carcinoma HeLa cells. in ICCBIKG 2023 : 2nd International Conference on Chemo and Bioinformatics : Book of Proceedings. 2023;:415-418.
doi:10.46793/ICCBI23.415C .

Čolović, Mirjana, Žakula, Jelena, Korićanac, Lela, Savić, Nada, Parac-Vogt, Tatjana, Krstić, Danijela Z., "In vitro cytotoxic activity of a monolacunary Wells-Dawson nanocluster against cervical carcinoma HeLa cells" in ICCBIKG 2023 : 2nd International Conference on Chemo and Bioinformatics : Book of Proceedings (2023):415-418,
https://doi.org/10.46793/ICCBI23.415C . .

TY  - CONF
AU  - Čolović, Mirjana
AU  - Korićanac, Lela
AU  - Žakula, Jelena
AU  - Savić, Nada
AU  - Parac-Vogt, Tatjana
AU  - Krstić, Danijela Z.
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12928
AB  - The objective of this study was to evaluate in vitro the antitumor properties of Fe(III)- substituted monolacunary Wells-Dawson polyoxotungstate, K7[FeIII(α2-P2W17O61)(H2O)] (FeWD) using cervical carcinoma HeLa cells as a model system. HeLa cells were exposed in vitro to FeWD within the concentration range from 0.001 to 1 mM, for 24, 48, and 72 hours. The studied Fe(III)- substituted polyoxotungstate affected HeLa cell viability in a concentration- and time-dependent manner. The obtained IC50 values (µM), as an indicator of the cytotoxic potential of FeWD, were: 16.64 ± 0.49, 10.75 ± 0.97, and 9.64 ± 0.19 for 24-, 48-, and 72-hour treatment, respectively. FeWD exhibited a stronger antitumor potential against HeLa cells than the structurally similar monolacunary Wells-Dawson polyoxotungstate, K10P2W17O61.20H2O (lacunary WD). Lacunary WD achieved IC50 at 24,11 µM after 24-hour exposure, which is about 44% higher concentration compared to the corresponding IC50 obtained for FeWD. This indicates that incorporating Fe(III) might be a new strategy for improving the antitumor efficacy of polyoxometalates as promising candidates for next-generation chemotherapeutics.
PB  - Kragujevac : Institute for Information Technologies, University of Kragujevac
C3  - ICCBIKG 2023 : 2nd International Conference on Chemo and Bioinformatics : Book of Proceedings
T1  - The influence of Fe(III) incorporation on anti-cancer potential of a Wells-Dawson nanocluster
SP  - 419
EP  - 422
DO  - 10.46793/ICCBI23.419C
ER  - 

@conference{
author = "Čolović, Mirjana and Korićanac, Lela and Žakula, Jelena and Savić, Nada and Parac-Vogt, Tatjana and Krstić, Danijela Z.",
year = "2023",
abstract = "The objective of this study was to evaluate in vitro the antitumor properties of Fe(III)- substituted monolacunary Wells-Dawson polyoxotungstate, K7[FeIII(α2-P2W17O61)(H2O)] (FeWD) using cervical carcinoma HeLa cells as a model system. HeLa cells were exposed in vitro to FeWD within the concentration range from 0.001 to 1 mM, for 24, 48, and 72 hours. The studied Fe(III)- substituted polyoxotungstate affected HeLa cell viability in a concentration- and time-dependent manner. The obtained IC50 values (µM), as an indicator of the cytotoxic potential of FeWD, were: 16.64 ± 0.49, 10.75 ± 0.97, and 9.64 ± 0.19 for 24-, 48-, and 72-hour treatment, respectively. FeWD exhibited a stronger antitumor potential against HeLa cells than the structurally similar monolacunary Wells-Dawson polyoxotungstate, K10P2W17O61.20H2O (lacunary WD). Lacunary WD achieved IC50 at 24,11 µM after 24-hour exposure, which is about 44% higher concentration compared to the corresponding IC50 obtained for FeWD. This indicates that incorporating Fe(III) might be a new strategy for improving the antitumor efficacy of polyoxometalates as promising candidates for next-generation chemotherapeutics.",
publisher = "Kragujevac : Institute for Information Technologies, University of Kragujevac",
journal = "ICCBIKG 2023 : 2nd International Conference on Chemo and Bioinformatics : Book of Proceedings",
title = "The influence of Fe(III) incorporation on anti-cancer potential of a Wells-Dawson nanocluster",
pages = "419-422",
doi = "10.46793/ICCBI23.419C"
}

Čolović, M., Korićanac, L., Žakula, J., Savić, N., Parac-Vogt, T.,& Krstić, D. Z.. (2023). The influence of Fe(III) incorporation on anti-cancer potential of a Wells-Dawson nanocluster. in ICCBIKG 2023 : 2nd International Conference on Chemo and Bioinformatics : Book of Proceedings
Kragujevac : Institute for Information Technologies, University of Kragujevac., 419-422.
https://doi.org/10.46793/ICCBI23.419C

Čolović M, Korićanac L, Žakula J, Savić N, Parac-Vogt T, Krstić DZ. The influence of Fe(III) incorporation on anti-cancer potential of a Wells-Dawson nanocluster. in ICCBIKG 2023 : 2nd International Conference on Chemo and Bioinformatics : Book of Proceedings. 2023;:419-422.
doi:10.46793/ICCBI23.419C .

Čolović, Mirjana, Korićanac, Lela, Žakula, Jelena, Savić, Nada, Parac-Vogt, Tatjana, Krstić, Danijela Z., "The influence of Fe(III) incorporation on anti-cancer potential of a Wells-Dawson nanocluster" in ICCBIKG 2023 : 2nd International Conference on Chemo and Bioinformatics : Book of Proceedings (2023):419-422,
https://doi.org/10.46793/ICCBI23.419C . .

TY  - CONF
AU  - Domijan, Ana-Marija
AU  - Gajski, Goran
AU  - Gerić, M.
AU  - Savić, Nada
AU  - Parac-Vogt, Tatjana
AU  - Krstić, Danijela
AU  - Čolović, Mirjana
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12926
AB  - In this study, prooxidative properties of three Wells-Dawson polyoxometalates (POMs) previously reported as promising contrast-enhancing staining agents for micro-computed tomography (microCT): parent Wells-Dawson POM α2-K6P2W18O62.14H2O (parent WD), monolacunary Wells-Dawson POM α2-K10P2W17O61.20H2O (lacunary WD), and 1:2 hafnium(IV)-substituted Wells-Dawson POM K16[Hf(α2-P2W17O61)2]·19H2O (Hf-WD 1:2), were evaluated in vitro. In this aim, malondialdehyde (MDA) level, as an indicator of prooxidant action and lipid peroxidation, was determined in human plasma after 24 h treatment with the POMs in the concentration range 1-100 μM at 37 °C. The results demonstrated that the studied POMs did not induce an increase in plasma lipid peroxidation level compared to the corresponding control. Thus, it could be concluded that the investigated POM-based contrast agent candidates for microCT are not sufficiently potent prooxidants capable to cause membrane damage and consequent toxic occurrences.
PB  - Belgrade : Society of Physical Chemists of Serbia
C3  - PHYSICAL CHEMISTRY 2022 : 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings
T1  - In vitro toxicity evaluation of potential contrast agents for micro-computed tomography: effect on cell membrane
VL  - 1
SP  - 283
EP  - 286
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12926
ER  - 

@conference{
author = "Domijan, Ana-Marija and Gajski, Goran and Gerić, M. and Savić, Nada and Parac-Vogt, Tatjana and Krstić, Danijela and Čolović, Mirjana",
year = "2022",
abstract = "In this study, prooxidative properties of three Wells-Dawson polyoxometalates (POMs) previously reported as promising contrast-enhancing staining agents for micro-computed tomography (microCT): parent Wells-Dawson POM α2-K6P2W18O62.14H2O (parent WD), monolacunary Wells-Dawson POM α2-K10P2W17O61.20H2O (lacunary WD), and 1:2 hafnium(IV)-substituted Wells-Dawson POM K16[Hf(α2-P2W17O61)2]·19H2O (Hf-WD 1:2), were evaluated in vitro. In this aim, malondialdehyde (MDA) level, as an indicator of prooxidant action and lipid peroxidation, was determined in human plasma after 24 h treatment with the POMs in the concentration range 1-100 μM at 37 °C. The results demonstrated that the studied POMs did not induce an increase in plasma lipid peroxidation level compared to the corresponding control. Thus, it could be concluded that the investigated POM-based contrast agent candidates for microCT are not sufficiently potent prooxidants capable to cause membrane damage and consequent toxic occurrences.",
publisher = "Belgrade : Society of Physical Chemists of Serbia",
journal = "PHYSICAL CHEMISTRY 2022 : 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings",
title = "In vitro toxicity evaluation of potential contrast agents for micro-computed tomography: effect on cell membrane",
volume = "1",
pages = "283-286",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12926"
}

Domijan, A., Gajski, G., Gerić, M., Savić, N., Parac-Vogt, T., Krstić, D.,& Čolović, M.. (2022). In vitro toxicity evaluation of potential contrast agents for micro-computed tomography: effect on cell membrane. in PHYSICAL CHEMISTRY 2022 : 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings
Belgrade : Society of Physical Chemists of Serbia., 1, 283-286.
https://hdl.handle.net/21.15107/rcub_vinar_12926

Domijan A, Gajski G, Gerić M, Savić N, Parac-Vogt T, Krstić D, Čolović M. In vitro toxicity evaluation of potential contrast agents for micro-computed tomography: effect on cell membrane. in PHYSICAL CHEMISTRY 2022 : 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings. 2022;1:283-286.
https://hdl.handle.net/21.15107/rcub_vinar_12926 .

Domijan, Ana-Marija, Gajski, Goran, Gerić, M., Savić, Nada, Parac-Vogt, Tatjana, Krstić, Danijela, Čolović, Mirjana, "In vitro toxicity evaluation of potential contrast agents for micro-computed tomography: effect on cell membrane" in PHYSICAL CHEMISTRY 2022 : 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings, 1 (2022):283-286,
https://hdl.handle.net/21.15107/rcub_vinar_12926 .

TY  - CONF
AU  - Čolović, Mirjana
AU  - Gajski, Goran
AU  - Gerić, M.
AU  - Savić, Nada
AU  - Krstić, Danijela
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12924
AB  - Cytotoxicity assessment in vitro of three Wells-Dawson polyoxometalates (POMs) as contrast-enhancing staining agent (CESA) candidates: parent Wells-Dawson POM α2-K6P2W18O62.14H2O (parent WD), monolacunary Wells-Dawson POM α2-K10P2W17O61.20H2O (lacunary WD), and 1:2 hafnium(IV)-substituted Wells-Dawson POM K16[Hf(α2-P2W17O61)2]·19H2O (Hf-WD 1:2), was carried out on healthy non-target human blood cells. Whole blood samples were treated with these POMs (1-100 μM) for 4 and 24 h at 37 °C. The results showed a time-dependent decrease of the peripheral blood mononuclear cell (PBMC) viability for all investigated polyoxotungstates. The 4 h treatment induced a significant cytotoxic effect only for the higher concentrations of Hf-WD 1:2, whereas 24 h exposure resulted in a concentration-dependent alteration of the cell viability. The most potent cytotoxic activity was obtained for Hf-WD 1:2 inducing a decrease of the cell viability from 25 to 45% compared to the corresponding control. The weakest effect was observed for parent WD, which resulted in no statistically significant difference in PBMC viability in respect to the control at the concentration of 1 μM. Finally, parent WD, lacunary WD, and Hf-WD 1:2 could not be considered safe from a cytotoxic point of view, thus further more extensive toxicity studies are needed.
PB  - Belgrade : Society of Physical Chemists of Serbia
C3  - PHYSICAL CHEMISTRY 2022 : 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings
T1  - Cytotoxicity evaluation of promising staining agents for contrast-enhanced microfocus computed tomography
VL  - 1
SP  - 275
EP  - 278
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12924
ER  - 

@conference{
author = "Čolović, Mirjana and Gajski, Goran and Gerić, M. and Savić, Nada and Krstić, Danijela",
year = "2022",
abstract = "Cytotoxicity assessment in vitro of three Wells-Dawson polyoxometalates (POMs) as contrast-enhancing staining agent (CESA) candidates: parent Wells-Dawson POM α2-K6P2W18O62.14H2O (parent WD), monolacunary Wells-Dawson POM α2-K10P2W17O61.20H2O (lacunary WD), and 1:2 hafnium(IV)-substituted Wells-Dawson POM K16[Hf(α2-P2W17O61)2]·19H2O (Hf-WD 1:2), was carried out on healthy non-target human blood cells. Whole blood samples were treated with these POMs (1-100 μM) for 4 and 24 h at 37 °C. The results showed a time-dependent decrease of the peripheral blood mononuclear cell (PBMC) viability for all investigated polyoxotungstates. The 4 h treatment induced a significant cytotoxic effect only for the higher concentrations of Hf-WD 1:2, whereas 24 h exposure resulted in a concentration-dependent alteration of the cell viability. The most potent cytotoxic activity was obtained for Hf-WD 1:2 inducing a decrease of the cell viability from 25 to 45% compared to the corresponding control. The weakest effect was observed for parent WD, which resulted in no statistically significant difference in PBMC viability in respect to the control at the concentration of 1 μM. Finally, parent WD, lacunary WD, and Hf-WD 1:2 could not be considered safe from a cytotoxic point of view, thus further more extensive toxicity studies are needed.",
publisher = "Belgrade : Society of Physical Chemists of Serbia",
journal = "PHYSICAL CHEMISTRY 2022 : 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings",
title = "Cytotoxicity evaluation of promising staining agents for contrast-enhanced microfocus computed tomography",
volume = "1",
pages = "275-278",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12924"
}

Čolović, M., Gajski, G., Gerić, M., Savić, N.,& Krstić, D.. (2022). Cytotoxicity evaluation of promising staining agents for contrast-enhanced microfocus computed tomography. in PHYSICAL CHEMISTRY 2022 : 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings
Belgrade : Society of Physical Chemists of Serbia., 1, 275-278.
https://hdl.handle.net/21.15107/rcub_vinar_12924

Čolović M, Gajski G, Gerić M, Savić N, Krstić D. Cytotoxicity evaluation of promising staining agents for contrast-enhanced microfocus computed tomography. in PHYSICAL CHEMISTRY 2022 : 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings. 2022;1:275-278.
https://hdl.handle.net/21.15107/rcub_vinar_12924 .

Čolović, Mirjana, Gajski, Goran, Gerić, M., Savić, Nada, Krstić, Danijela, "Cytotoxicity evaluation of promising staining agents for contrast-enhanced microfocus computed tomography" in PHYSICAL CHEMISTRY 2022 : 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings, 1 (2022):275-278,
https://hdl.handle.net/21.15107/rcub_vinar_12924 .

TY  - CONF
AU  - Čolović, Mirjana
AU  - Domijan, Ana-Marija
AU  - Gajski, Goran
AU  - Gerić, M.
AU  - Parac-Vogt, Tatjana
AU  - Krstić, Danijela
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12925
AB  - The aim of this study to assess in vitro prooxidative properties of three polyoxometalate (POM)-based species that were found as potential contrast-enhancing staining agents for micro-computed tomography (microCT) to visualize kidney and bone tissues: parent Wells-Dawson POM α2-K6P2W18O62.14H2O (parent WD), monolacunary Wells-Dawson POM α2-K10P2W17O61.20H2O (lacunary WD), and 1:2 hafnium(IV)-substituted Wells-Dawson POM K16[Hf(α2-P2W17O61)2]·19H2O (Hf-WD 1:2). Thus, reduced glutathione (GSH) concentration, as a major antioxidant to prevent reactive oxygen species (ROS) attack and an indicator of oxidative stress, was followed in human plasma after 24 h exposure to the POMs within the concentration range 1-100 μM at 37 °C. The promising contrast agents exhibited various prooxidative properties. Parent WD did not significantly influence GSH level, thus prooxidative properties could not be associated with this POM species. On the contrary, Hf-WD 1:2 exposure resulted in a significant decrease in GSH concentration in human plasma compared to untreated control. Accordingly, Hf-WD 1:2 might be regarded as a prooxidant agent that could cause oxidative stress and consequent toxic occurrences. Nevertheless, additional studies on other relevant oxidative stress parameters are needed to confirm this assumption.
PB  - Belgrade : Society of Physical Chemists of Serbia
C3  - PHYSICAL CHEMISTRY 2022 : 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings
T1  - Prooxidative properties of contrast agent candidates for micro-computed tomography
VL  - 1
SP  - 279
EP  - 282
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12925
ER  - 

@conference{
author = "Čolović, Mirjana and Domijan, Ana-Marija and Gajski, Goran and Gerić, M. and Parac-Vogt, Tatjana and Krstić, Danijela",
year = "2022",
abstract = "The aim of this study to assess in vitro prooxidative properties of three polyoxometalate (POM)-based species that were found as potential contrast-enhancing staining agents for micro-computed tomography (microCT) to visualize kidney and bone tissues: parent Wells-Dawson POM α2-K6P2W18O62.14H2O (parent WD), monolacunary Wells-Dawson POM α2-K10P2W17O61.20H2O (lacunary WD), and 1:2 hafnium(IV)-substituted Wells-Dawson POM K16[Hf(α2-P2W17O61)2]·19H2O (Hf-WD 1:2). Thus, reduced glutathione (GSH) concentration, as a major antioxidant to prevent reactive oxygen species (ROS) attack and an indicator of oxidative stress, was followed in human plasma after 24 h exposure to the POMs within the concentration range 1-100 μM at 37 °C. The promising contrast agents exhibited various prooxidative properties. Parent WD did not significantly influence GSH level, thus prooxidative properties could not be associated with this POM species. On the contrary, Hf-WD 1:2 exposure resulted in a significant decrease in GSH concentration in human plasma compared to untreated control. Accordingly, Hf-WD 1:2 might be regarded as a prooxidant agent that could cause oxidative stress and consequent toxic occurrences. Nevertheless, additional studies on other relevant oxidative stress parameters are needed to confirm this assumption.",
publisher = "Belgrade : Society of Physical Chemists of Serbia",
journal = "PHYSICAL CHEMISTRY 2022 : 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings",
title = "Prooxidative properties of contrast agent candidates for micro-computed tomography",
volume = "1",
pages = "279-282",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12925"
}

Čolović, M., Domijan, A., Gajski, G., Gerić, M., Parac-Vogt, T.,& Krstić, D.. (2022). Prooxidative properties of contrast agent candidates for micro-computed tomography. in PHYSICAL CHEMISTRY 2022 : 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings
Belgrade : Society of Physical Chemists of Serbia., 1, 279-282.
https://hdl.handle.net/21.15107/rcub_vinar_12925

Čolović M, Domijan A, Gajski G, Gerić M, Parac-Vogt T, Krstić D. Prooxidative properties of contrast agent candidates for micro-computed tomography. in PHYSICAL CHEMISTRY 2022 : 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings. 2022;1:279-282.
https://hdl.handle.net/21.15107/rcub_vinar_12925 .

Čolović, Mirjana, Domijan, Ana-Marija, Gajski, Goran, Gerić, M., Parac-Vogt, Tatjana, Krstić, Danijela, "Prooxidative properties of contrast agent candidates for micro-computed tomography" in PHYSICAL CHEMISTRY 2022 : 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings, 1 (2022):279-282,
https://hdl.handle.net/21.15107/rcub_vinar_12925 .

TY  - CONF
AU  - Čolović, Mirjana
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12921
AB  - Cytotoxicity and prooxidative properties evaluation of three Wells-Dawson polyoxotungstates that were published as potential contrast-enhancing staining agent (CESA) candidates for micro-computed tomography (microCT): parent Wells-Dawson POM α2-K6P2W18O62.14H2O (parent WD), monolacunary Wells-Dawson POM α2-K10P2W17O61.20H2O (lacunary WD), and 1:2 hafnium(IV)-substituted Wells-Dawson POM K16[Hf(α2-P2W17O61)2]·19H2O (Hf-WD 1:2), was carried out in vitro. Oxidative stress indicators, reduced glutathione (GSH) and malondialdehyde (MDA) levels were determined in human blood plasma after 4 and 24 h treatment with the selected polyoxotungstates, within the concentration range 1-100 μM at 37 °C, and polyoxotungstate-induced cytotoxicity was assessed by monitoring cell viability in peripheral blood mononuclear cells (PBMCs). The results demonstrated that each of the studied promising CESAs resulted in a decrease of human PBMC viability in concentration- and time-dependent manner, and Hf-WD 1:2 exhibited the strongest cytotoxic properties inducing up to 50% decrease of the cell viability related to corresponding control. However, only Hf-WD 1:2 might be considered a potential prooxidant that resulted in a significant decrease of human plasma GSH level, whereas none of the investigated polyoxotungstates did not cause membrane lipid damage. Conclusively, parent WD, lacunary WD, and Hf-WD 1:2 could not be considered safe primarily from a cytotoxic point of view, thus more extensive in vitro and in vivo studies are needed for the toxicological profile assessment of the studied promising CESA candidates for the soft tissue visualization using microCT.
PB  - Belgrade : Society of Physical Chemists of Serbia
C3  - PHYSICAL CHEMISTRY 2022 : 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings
T1  - Toxicity evaluation of promising contrast-enhancing staining agents
VL  - 2
SP  - 573
EP  - 576
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12921
ER  - 

@conference{
author = "Čolović, Mirjana",
year = "2022",
abstract = "Cytotoxicity and prooxidative properties evaluation of three Wells-Dawson polyoxotungstates that were published as potential contrast-enhancing staining agent (CESA) candidates for micro-computed tomography (microCT): parent Wells-Dawson POM α2-K6P2W18O62.14H2O (parent WD), monolacunary Wells-Dawson POM α2-K10P2W17O61.20H2O (lacunary WD), and 1:2 hafnium(IV)-substituted Wells-Dawson POM K16[Hf(α2-P2W17O61)2]·19H2O (Hf-WD 1:2), was carried out in vitro. Oxidative stress indicators, reduced glutathione (GSH) and malondialdehyde (MDA) levels were determined in human blood plasma after 4 and 24 h treatment with the selected polyoxotungstates, within the concentration range 1-100 μM at 37 °C, and polyoxotungstate-induced cytotoxicity was assessed by monitoring cell viability in peripheral blood mononuclear cells (PBMCs). The results demonstrated that each of the studied promising CESAs resulted in a decrease of human PBMC viability in concentration- and time-dependent manner, and Hf-WD 1:2 exhibited the strongest cytotoxic properties inducing up to 50% decrease of the cell viability related to corresponding control. However, only Hf-WD 1:2 might be considered a potential prooxidant that resulted in a significant decrease of human plasma GSH level, whereas none of the investigated polyoxotungstates did not cause membrane lipid damage. Conclusively, parent WD, lacunary WD, and Hf-WD 1:2 could not be considered safe primarily from a cytotoxic point of view, thus more extensive in vitro and in vivo studies are needed for the toxicological profile assessment of the studied promising CESA candidates for the soft tissue visualization using microCT.",
publisher = "Belgrade : Society of Physical Chemists of Serbia",
journal = "PHYSICAL CHEMISTRY 2022 : 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings",
title = "Toxicity evaluation of promising contrast-enhancing staining agents",
volume = "2",
pages = "573-576",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12921"
}

Čolović, M.. (2022). Toxicity evaluation of promising contrast-enhancing staining agents. in PHYSICAL CHEMISTRY 2022 : 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings
Belgrade : Society of Physical Chemists of Serbia., 2, 573-576.
https://hdl.handle.net/21.15107/rcub_vinar_12921

Čolović M. Toxicity evaluation of promising contrast-enhancing staining agents. in PHYSICAL CHEMISTRY 2022 : 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings. 2022;2:573-576.
https://hdl.handle.net/21.15107/rcub_vinar_12921 .

Čolović, Mirjana, "Toxicity evaluation of promising contrast-enhancing staining agents" in PHYSICAL CHEMISTRY 2022 : 16th International Conference on Fundamental and Applied Aspects of Physical Chemistry : Proceedings, 2 (2022):573-576,
https://hdl.handle.net/21.15107/rcub_vinar_12921 .