TY  - CONF
AU  - Butulija, Svetlana
AU  - Filipović Tričković, Jelena
AU  - Valenta Šobot, Ana
AU  - Todorović, Bratislav
AU  - Petrović, Sanja
AU  - Ilić, Bojana
AU  - Zmejkoski, Danica
AU  - Matović, Branko
PY  - 2024
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/13167
PB  - Belgrade : Vinča Institute of Nuclear Sciences - National Institute of thе Republic of Serbia, University of Belgrade
PB  - Belgrade : Serbian Society for Innovative Materials in Extreme Conditions (SIM-EXTREME)
C3  - IMEC2024 - 2nd International Conference on Innovative Materials in Extreme Conditions : Book of abstracts
T1  - Bacterial Cellulose-Cerium Oxide Hydrogel for Tailored Redox Balance in Biomedical Extremes
SP  - 73
EP  - 73
UR  - https://hdl.handle.net/21.15107/rcub_vinar_13167
ER  - 

@conference{
author = "Butulija, Svetlana and Filipović Tričković, Jelena and Valenta Šobot, Ana and Todorović, Bratislav and Petrović, Sanja and Ilić, Bojana and Zmejkoski, Danica and Matović, Branko",
year = "2024",
publisher = "Belgrade : Vinča Institute of Nuclear Sciences - National Institute of thе Republic of Serbia, University of Belgrade, Belgrade : Serbian Society for Innovative Materials in Extreme Conditions (SIM-EXTREME)",
journal = "IMEC2024 - 2nd International Conference on Innovative Materials in Extreme Conditions : Book of abstracts",
title = "Bacterial Cellulose-Cerium Oxide Hydrogel for Tailored Redox Balance in Biomedical Extremes",
pages = "73-73",
url = "https://hdl.handle.net/21.15107/rcub_vinar_13167"
}

Butulija, S., Filipović Tričković, J., Valenta Šobot, A., Todorović, B., Petrović, S., Ilić, B., Zmejkoski, D.,& Matović, B.. (2024). Bacterial Cellulose-Cerium Oxide Hydrogel for Tailored Redox Balance in Biomedical Extremes. in IMEC2024 - 2nd International Conference on Innovative Materials in Extreme Conditions : Book of abstracts
Belgrade : Vinča Institute of Nuclear Sciences - National Institute of thе Republic of Serbia, University of Belgrade., 73-73.
https://hdl.handle.net/21.15107/rcub_vinar_13167

Butulija S, Filipović Tričković J, Valenta Šobot A, Todorović B, Petrović S, Ilić B, Zmejkoski D, Matović B. Bacterial Cellulose-Cerium Oxide Hydrogel for Tailored Redox Balance in Biomedical Extremes. in IMEC2024 - 2nd International Conference on Innovative Materials in Extreme Conditions : Book of abstracts. 2024;:73-73.
https://hdl.handle.net/21.15107/rcub_vinar_13167 .

Butulija, Svetlana, Filipović Tričković, Jelena, Valenta Šobot, Ana, Todorović, Bratislav, Petrović, Sanja, Ilić, Bojana, Zmejkoski, Danica, Matović, Branko, "Bacterial Cellulose-Cerium Oxide Hydrogel for Tailored Redox Balance in Biomedical Extremes" in IMEC2024 - 2nd International Conference on Innovative Materials in Extreme Conditions : Book of abstracts (2024):73-73,
https://hdl.handle.net/21.15107/rcub_vinar_13167 .

TY  - CONF
AU  - Ilić, Bojana
AU  - Petrović, Božana
AU  - Marinković, Jelena
AU  - Filipović Tričković, Jelena
AU  - Miletić Vukajlović, Jadranka
PY  - 2023
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12728
AB  - Objectives: The main purpose of orthodontic treatment (OT) is to accomplish an optimal occlusal relationship in order to obtain adequate oral function and aesthetic appearance. Under optimal economic conditions, demand for OT reaches at least 35%, but in higher socioeconomic areas in US more than 50% of children are receiving orthodontic care. Acceptance of OT in Europe, like in western population and Scandinavian countries, is at similar levels. Very desirable mechanical characteristics, such as shape memory effect and superelasticity, expanded the use of nitinol (NiTi) archwires in orthodontics significantly. The complex conditions present in the oral cavity, including biofilm formation on the exposed surfaces, substantially alter the surface and structural properties of the NiTi archwires compromising the safety of OT. The necessity for developing novel material coating that would decrease Ni release and improve biological properties is of a great importance. Materials-Methods: Copper doped titanium nitride films (TiN-Cu) on the surface of NiTi archwires were obtained by combination of the cathodic arc evaporation and DC magnetron sputtering. The physicochemical characterization was performed using energy-dispersive X-ray spectroscopy (EDS) and X-ray diffraction (XRD). Ion release was assessed using inductively coupled plasma optical emission spectrometry (ICP-OES). The cytotoxicity of NiTi archwires, stainless steel (SS) archwires and TiN-Cu coated archwires was investigated using 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyl tetrazolium bromide (MTT) test. In order to evaluate bacterial adhesion and biofilm formation, the following strains were used: Streptococcus mutans and Streptococcus mitis. Results: Physicochemical characterization revealed well-designed coatings with the presence of TiN phase with incorporated Cu. The release of Ni was the lowest regarding TiN-Cunanocoated archwires (p < 0.05) and increased in acidic conditions, while the release of Ti was constant. Contrary, the release of Cu was higher in neutral conditions and decreased during the observation time (p < 0.05). The cytotoxicity was the lowest in 28-day eluates of TiN-Cu-nanocoated archwires (p < 0.05). The coating inhibited the adhesion and growth of bacteria such as Streptococcus mitis and Streptococcus mutans (p < 0.05). Conclusion: Taking into account the results of cytotoxicity test and biofilm formation, TiN-Cunanocoated archwires may be considered as a good candidate for further clinical investigations.
C3  - BaSS : 27th  International Balkan Congress Congress - “Past, Present and Future of Dental implants and Gerodontology“ : Book of abstracts
T1  - Biological properties of nitinol archwires coated with titanium nitride- copper films
SP  - 87
EP  - 87
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12728
ER  - 

@conference{
author = "Ilić, Bojana and Petrović, Božana and Marinković, Jelena and Filipović Tričković, Jelena and Miletić Vukajlović, Jadranka",
year = "2023",
abstract = "Objectives: The main purpose of orthodontic treatment (OT) is to accomplish an optimal occlusal relationship in order to obtain adequate oral function and aesthetic appearance. Under optimal economic conditions, demand for OT reaches at least 35%, but in higher socioeconomic areas in US more than 50% of children are receiving orthodontic care. Acceptance of OT in Europe, like in western population and Scandinavian countries, is at similar levels. Very desirable mechanical characteristics, such as shape memory effect and superelasticity, expanded the use of nitinol (NiTi) archwires in orthodontics significantly. The complex conditions present in the oral cavity, including biofilm formation on the exposed surfaces, substantially alter the surface and structural properties of the NiTi archwires compromising the safety of OT. The necessity for developing novel material coating that would decrease Ni release and improve biological properties is of a great importance. Materials-Methods: Copper doped titanium nitride films (TiN-Cu) on the surface of NiTi archwires were obtained by combination of the cathodic arc evaporation and DC magnetron sputtering. The physicochemical characterization was performed using energy-dispersive X-ray spectroscopy (EDS) and X-ray diffraction (XRD). Ion release was assessed using inductively coupled plasma optical emission spectrometry (ICP-OES). The cytotoxicity of NiTi archwires, stainless steel (SS) archwires and TiN-Cu coated archwires was investigated using 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyl tetrazolium bromide (MTT) test. In order to evaluate bacterial adhesion and biofilm formation, the following strains were used: Streptococcus mutans and Streptococcus mitis. Results: Physicochemical characterization revealed well-designed coatings with the presence of TiN phase with incorporated Cu. The release of Ni was the lowest regarding TiN-Cunanocoated archwires (p < 0.05) and increased in acidic conditions, while the release of Ti was constant. Contrary, the release of Cu was higher in neutral conditions and decreased during the observation time (p < 0.05). The cytotoxicity was the lowest in 28-day eluates of TiN-Cu-nanocoated archwires (p < 0.05). The coating inhibited the adhesion and growth of bacteria such as Streptococcus mitis and Streptococcus mutans (p < 0.05). Conclusion: Taking into account the results of cytotoxicity test and biofilm formation, TiN-Cunanocoated archwires may be considered as a good candidate for further clinical investigations.",
journal = "BaSS : 27th  International Balkan Congress Congress - “Past, Present and Future of Dental implants and Gerodontology“ : Book of abstracts",
title = "Biological properties of nitinol archwires coated with titanium nitride- copper films",
pages = "87-87",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12728"
}

Ilić, B., Petrović, B., Marinković, J., Filipović Tričković, J.,& Miletić Vukajlović, J.. (2023). Biological properties of nitinol archwires coated with titanium nitride- copper films. in BaSS : 27th  International Balkan Congress Congress - “Past, Present and Future of Dental implants and Gerodontology“ : Book of abstracts, 87-87.
https://hdl.handle.net/21.15107/rcub_vinar_12728

Ilić B, Petrović B, Marinković J, Filipović Tričković J, Miletić Vukajlović J. Biological properties of nitinol archwires coated with titanium nitride- copper films. in BaSS : 27th  International Balkan Congress Congress - “Past, Present and Future of Dental implants and Gerodontology“ : Book of abstracts. 2023;:87-87.
https://hdl.handle.net/21.15107/rcub_vinar_12728 .

Ilić, Bojana, Petrović, Božana, Marinković, Jelena, Filipović Tričković, Jelena, Miletić Vukajlović, Jadranka, "Biological properties of nitinol archwires coated with titanium nitride- copper films" in BaSS : 27th  International Balkan Congress Congress - “Past, Present and Future of Dental implants and Gerodontology“ : Book of abstracts (2023):87-87,
https://hdl.handle.net/21.15107/rcub_vinar_12728 .

TY  - JOUR
AU  - Joksimović, Nenad
AU  - Petronijević, Jelena
AU  - Radisavljević, Snežana
AU  - Petrović, Biljana
AU  - Mihajlović, Kristina
AU  - Janković, Nenad
AU  - Milović, Emilija
AU  - Milivojević, Dušan
AU  - Ilić, Bojana
AU  - Đurić, Ana
PY  - 2022
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/10518
AB  - Considering the urgency of finding a cure for vicious diseases such as tumors, we have synthesized and characterized a small series of new copper(ii) complexes with biologically important ligands such as acylpyruvate. In addition to this, we used another four copper(ii) complexes, with ligands of the same type to examine the antitumor potential. The antitumor potential of the copper(ii) complexes was examined on three tumor cell lines and one normal human cell line using the MTT assay. All seven tested complexes showed very good cytotoxic effects. Two copper complexes that showed the best antitumor potential were selected for further testing that showed the best potential for potential application in the future. The mechanism of activity of these complexes was examined in detail using tests such as cell cycle, ROS level, oxidative DNA damage, and proteins related to hypoxia analysis. In addition, we examined the binding abilities of these complexes with biomolecules (Guo, Ino, 5′-GMP, BSA, and DNA). The results showed that the tested compounds bind strongly to DNA molecules through intercalation. Also, it has been shown that the tested compounds adequately bind to the BSA molecule, which indicates an even greater potential for some future application of these compounds in clinical practice. © 2022 The Royal Society of Chemistry.
T2  - RSC Advances
T1  - Synthesis, characterization, antitumor potential, and investigation of mechanism of action of copper(ii) complexes with acylpyruvates as ligands: interactions with biomolecules and kinetic study
VL  - 12
IS  - 47
SP  - 30501
EP  - 30513
DO  - 10.1039/d2ra05797b
ER  - 

@article{
author = "Joksimović, Nenad and Petronijević, Jelena and Radisavljević, Snežana and Petrović, Biljana and Mihajlović, Kristina and Janković, Nenad and Milović, Emilija and Milivojević, Dušan and Ilić, Bojana and Đurić, Ana",
year = "2022",
abstract = "Considering the urgency of finding a cure for vicious diseases such as tumors, we have synthesized and characterized a small series of new copper(ii) complexes with biologically important ligands such as acylpyruvate. In addition to this, we used another four copper(ii) complexes, with ligands of the same type to examine the antitumor potential. The antitumor potential of the copper(ii) complexes was examined on three tumor cell lines and one normal human cell line using the MTT assay. All seven tested complexes showed very good cytotoxic effects. Two copper complexes that showed the best antitumor potential were selected for further testing that showed the best potential for potential application in the future. The mechanism of activity of these complexes was examined in detail using tests such as cell cycle, ROS level, oxidative DNA damage, and proteins related to hypoxia analysis. In addition, we examined the binding abilities of these complexes with biomolecules (Guo, Ino, 5′-GMP, BSA, and DNA). The results showed that the tested compounds bind strongly to DNA molecules through intercalation. Also, it has been shown that the tested compounds adequately bind to the BSA molecule, which indicates an even greater potential for some future application of these compounds in clinical practice. © 2022 The Royal Society of Chemistry.",
journal = "RSC Advances",
title = "Synthesis, characterization, antitumor potential, and investigation of mechanism of action of copper(ii) complexes with acylpyruvates as ligands: interactions with biomolecules and kinetic study",
volume = "12",
number = "47",
pages = "30501-30513",
doi = "10.1039/d2ra05797b"
}

Joksimović, N., Petronijević, J., Radisavljević, S., Petrović, B., Mihajlović, K., Janković, N., Milović, E., Milivojević, D., Ilić, B.,& Đurić, A.. (2022). Synthesis, characterization, antitumor potential, and investigation of mechanism of action of copper(ii) complexes with acylpyruvates as ligands: interactions with biomolecules and kinetic study. in RSC Advances, 12(47), 30501-30513.
https://doi.org/10.1039/d2ra05797b

Joksimović N, Petronijević J, Radisavljević S, Petrović B, Mihajlović K, Janković N, Milović E, Milivojević D, Ilić B, Đurić A. Synthesis, characterization, antitumor potential, and investigation of mechanism of action of copper(ii) complexes with acylpyruvates as ligands: interactions with biomolecules and kinetic study. in RSC Advances. 2022;12(47):30501-30513.
doi:10.1039/d2ra05797b .

Joksimović, Nenad, Petronijević, Jelena, Radisavljević, Snežana, Petrović, Biljana, Mihajlović, Kristina, Janković, Nenad, Milović, Emilija, Milivojević, Dušan, Ilić, Bojana, Đurić, Ana, "Synthesis, characterization, antitumor potential, and investigation of mechanism of action of copper(ii) complexes with acylpyruvates as ligands: interactions with biomolecules and kinetic study" in RSC Advances, 12, no. 47 (2022):30501-30513,
https://doi.org/10.1039/d2ra05797b . .