Biological properties of nitinol archwires coated with titanium nitride- copper films
Аутори
Ilić, BojanaPetrović, Božana
Marinković, Jelena
Filipović Tričković, Jelena
Miletić Vukajlović, Jadranka
Конференцијски прилог (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Objectives: The main purpose of orthodontic treatment (OT) is to accomplish an optimal occlusal relationship in order to obtain adequate oral function and aesthetic appearance. Under optimal economic conditions, demand for OT reaches at least 35%, but in higher socioeconomic areas in US more than 50% of children are receiving orthodontic care. Acceptance of OT in Europe, like in western population and Scandinavian countries, is at similar levels. Very desirable mechanical characteristics, such as shape memory effect and superelasticity, expanded the use of nitinol (NiTi) archwires in orthodontics significantly. The complex conditions present in the oral cavity, including biofilm formation on the exposed surfaces, substantially alter the surface and structural properties of the NiTi archwires compromising the safety of OT. The necessity for developing novel material coating that would decrease Ni release and improve biological properties is of a great importance. Materials-Methods: Copp...er doped titanium nitride films (TiN-Cu) on the surface of NiTi archwires were obtained by combination of the cathodic arc evaporation and DC magnetron sputtering. The physicochemical characterization was performed using energy-dispersive X-ray spectroscopy (EDS) and X-ray diffraction (XRD). Ion release was assessed using inductively coupled plasma optical emission spectrometry (ICP-OES). The cytotoxicity of NiTi archwires, stainless steel (SS) archwires and TiN-Cu coated archwires was investigated using 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyl tetrazolium bromide (MTT) test. In order to evaluate bacterial adhesion and biofilm formation, the following strains were used: Streptococcus mutans and Streptococcus mitis. Results: Physicochemical characterization revealed well-designed coatings with the presence of TiN phase with incorporated Cu. The release of Ni was the lowest regarding TiN-Cunanocoated archwires (p < 0.05) and increased in acidic conditions, while the release of Ti was constant. Contrary, the release of Cu was higher in neutral conditions and decreased during the observation time (p < 0.05). The cytotoxicity was the lowest in 28-day eluates of TiN-Cu-nanocoated archwires (p < 0.05). The coating inhibited the adhesion and growth of bacteria such as Streptococcus mitis and Streptococcus mutans (p < 0.05). Conclusion: Taking into account the results of cytotoxicity test and biofilm formation, TiN-Cunanocoated archwires may be considered as a good candidate for further clinical investigations.
Кључне речи:
antibacterial activity / orthodontic archwires / Streptococcus mutans / nanocoatingsИзвор:
BaSS : 27th International Balkan Congress Congress - “Past, Present and Future of Dental implants and Gerodontology“ : Book of abstracts, 2023, 87-87Напомена:
- 27th BaSS : November 9-11, Istanbul, Turkey, 2023.
Колекције
Институција/група
VinčaTY - CONF AU - Ilić, Bojana AU - Petrović, Božana AU - Marinković, Jelena AU - Filipović Tričković, Jelena AU - Miletić Vukajlović, Jadranka PY - 2023 UR - https://vinar.vin.bg.ac.rs/handle/123456789/12728 AB - Objectives: The main purpose of orthodontic treatment (OT) is to accomplish an optimal occlusal relationship in order to obtain adequate oral function and aesthetic appearance. Under optimal economic conditions, demand for OT reaches at least 35%, but in higher socioeconomic areas in US more than 50% of children are receiving orthodontic care. Acceptance of OT in Europe, like in western population and Scandinavian countries, is at similar levels. Very desirable mechanical characteristics, such as shape memory effect and superelasticity, expanded the use of nitinol (NiTi) archwires in orthodontics significantly. The complex conditions present in the oral cavity, including biofilm formation on the exposed surfaces, substantially alter the surface and structural properties of the NiTi archwires compromising the safety of OT. The necessity for developing novel material coating that would decrease Ni release and improve biological properties is of a great importance. Materials-Methods: Copper doped titanium nitride films (TiN-Cu) on the surface of NiTi archwires were obtained by combination of the cathodic arc evaporation and DC magnetron sputtering. The physicochemical characterization was performed using energy-dispersive X-ray spectroscopy (EDS) and X-ray diffraction (XRD). Ion release was assessed using inductively coupled plasma optical emission spectrometry (ICP-OES). The cytotoxicity of NiTi archwires, stainless steel (SS) archwires and TiN-Cu coated archwires was investigated using 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyl tetrazolium bromide (MTT) test. In order to evaluate bacterial adhesion and biofilm formation, the following strains were used: Streptococcus mutans and Streptococcus mitis. Results: Physicochemical characterization revealed well-designed coatings with the presence of TiN phase with incorporated Cu. The release of Ni was the lowest regarding TiN-Cunanocoated archwires (p < 0.05) and increased in acidic conditions, while the release of Ti was constant. Contrary, the release of Cu was higher in neutral conditions and decreased during the observation time (p < 0.05). The cytotoxicity was the lowest in 28-day eluates of TiN-Cu-nanocoated archwires (p < 0.05). The coating inhibited the adhesion and growth of bacteria such as Streptococcus mitis and Streptococcus mutans (p < 0.05). Conclusion: Taking into account the results of cytotoxicity test and biofilm formation, TiN-Cunanocoated archwires may be considered as a good candidate for further clinical investigations. C3 - BaSS : 27th International Balkan Congress Congress - “Past, Present and Future of Dental implants and Gerodontology“ : Book of abstracts T1 - Biological properties of nitinol archwires coated with titanium nitride- copper films SP - 87 EP - 87 UR - https://hdl.handle.net/21.15107/rcub_vinar_12728 ER -
@conference{ author = "Ilić, Bojana and Petrović, Božana and Marinković, Jelena and Filipović Tričković, Jelena and Miletić Vukajlović, Jadranka", year = "2023", abstract = "Objectives: The main purpose of orthodontic treatment (OT) is to accomplish an optimal occlusal relationship in order to obtain adequate oral function and aesthetic appearance. Under optimal economic conditions, demand for OT reaches at least 35%, but in higher socioeconomic areas in US more than 50% of children are receiving orthodontic care. Acceptance of OT in Europe, like in western population and Scandinavian countries, is at similar levels. Very desirable mechanical characteristics, such as shape memory effect and superelasticity, expanded the use of nitinol (NiTi) archwires in orthodontics significantly. The complex conditions present in the oral cavity, including biofilm formation on the exposed surfaces, substantially alter the surface and structural properties of the NiTi archwires compromising the safety of OT. The necessity for developing novel material coating that would decrease Ni release and improve biological properties is of a great importance. Materials-Methods: Copper doped titanium nitride films (TiN-Cu) on the surface of NiTi archwires were obtained by combination of the cathodic arc evaporation and DC magnetron sputtering. The physicochemical characterization was performed using energy-dispersive X-ray spectroscopy (EDS) and X-ray diffraction (XRD). Ion release was assessed using inductively coupled plasma optical emission spectrometry (ICP-OES). The cytotoxicity of NiTi archwires, stainless steel (SS) archwires and TiN-Cu coated archwires was investigated using 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyl tetrazolium bromide (MTT) test. In order to evaluate bacterial adhesion and biofilm formation, the following strains were used: Streptococcus mutans and Streptococcus mitis. Results: Physicochemical characterization revealed well-designed coatings with the presence of TiN phase with incorporated Cu. The release of Ni was the lowest regarding TiN-Cunanocoated archwires (p < 0.05) and increased in acidic conditions, while the release of Ti was constant. Contrary, the release of Cu was higher in neutral conditions and decreased during the observation time (p < 0.05). The cytotoxicity was the lowest in 28-day eluates of TiN-Cu-nanocoated archwires (p < 0.05). The coating inhibited the adhesion and growth of bacteria such as Streptococcus mitis and Streptococcus mutans (p < 0.05). Conclusion: Taking into account the results of cytotoxicity test and biofilm formation, TiN-Cunanocoated archwires may be considered as a good candidate for further clinical investigations.", journal = "BaSS : 27th International Balkan Congress Congress - “Past, Present and Future of Dental implants and Gerodontology“ : Book of abstracts", title = "Biological properties of nitinol archwires coated with titanium nitride- copper films", pages = "87-87", url = "https://hdl.handle.net/21.15107/rcub_vinar_12728" }
Ilić, B., Petrović, B., Marinković, J., Filipović Tričković, J.,& Miletić Vukajlović, J.. (2023). Biological properties of nitinol archwires coated with titanium nitride- copper films. in BaSS : 27th International Balkan Congress Congress - “Past, Present and Future of Dental implants and Gerodontology“ : Book of abstracts, 87-87. https://hdl.handle.net/21.15107/rcub_vinar_12728
Ilić B, Petrović B, Marinković J, Filipović Tričković J, Miletić Vukajlović J. Biological properties of nitinol archwires coated with titanium nitride- copper films. in BaSS : 27th International Balkan Congress Congress - “Past, Present and Future of Dental implants and Gerodontology“ : Book of abstracts. 2023;:87-87. https://hdl.handle.net/21.15107/rcub_vinar_12728 .
Ilić, Bojana, Petrović, Božana, Marinković, Jelena, Filipović Tričković, Jelena, Miletić Vukajlović, Jadranka, "Biological properties of nitinol archwires coated with titanium nitride- copper films" in BaSS : 27th International Balkan Congress Congress - “Past, Present and Future of Dental implants and Gerodontology“ : Book of abstracts (2023):87-87, https://hdl.handle.net/21.15107/rcub_vinar_12728 .