TY  - CONF
AU  - Jotić, Ana
AU  - Kuveljić, Jovana
AU  - Kolaković, Ana
AU  - Kolić, Ivana
AU  - Živković, Maja
AU  - Jesić, Snežana
AU  - Stanković, Aleksandra
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12387
AB  - Toll like receptors (TLRs) are the pattern recognition receptors, important for the innate immune system, the first line of defense against bacterial infections which are the main cause of otitis media (OM). Our aim was to investigate the association of TLR4 (Thr399Ile and Asp299Gly) and TLR2 (Arg753Gln) most common polymorphisms with OM prevalence as well as with morphologic changes of middle ear during chronic otitis media. We had 111 controls and 186 patients divided into three groups of COM: nonsuppurative OM, suppurative OM and cholesteatoma. Frequencies of the genotypes of the TLR 2 gene polymorphism were significantly different between men and women having nonsuppurative OM (p=0.03).
PB  - Belgrade : Serbian Genetic Society
C3  - V Congress of the Serbian Genetic Society : Book of abstracts
T1  - Toll like receptors 2 and 4 polymorphisms in chronic otitis media
SP  - 52
EP  - 52
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12387
ER  - 

@conference{
author = "Jotić, Ana and Kuveljić, Jovana and Kolaković, Ana and Kolić, Ivana and Živković, Maja and Jesić, Snežana and Stanković, Aleksandra",
year = "2014",
abstract = "Toll like receptors (TLRs) are the pattern recognition receptors, important for the innate immune system, the first line of defense against bacterial infections which are the main cause of otitis media (OM). Our aim was to investigate the association of TLR4 (Thr399Ile and Asp299Gly) and TLR2 (Arg753Gln) most common polymorphisms with OM prevalence as well as with morphologic changes of middle ear during chronic otitis media. We had 111 controls and 186 patients divided into three groups of COM: nonsuppurative OM, suppurative OM and cholesteatoma. Frequencies of the genotypes of the TLR 2 gene polymorphism were significantly different between men and women having nonsuppurative OM (p=0.03).",
publisher = "Belgrade : Serbian Genetic Society",
journal = "V Congress of the Serbian Genetic Society : Book of abstracts",
title = "Toll like receptors 2 and 4 polymorphisms in chronic otitis media",
pages = "52-52",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12387"
}

Jotić, A., Kuveljić, J., Kolaković, A., Kolić, I., Živković, M., Jesić, S.,& Stanković, A.. (2014). Toll like receptors 2 and 4 polymorphisms in chronic otitis media. in V Congress of the Serbian Genetic Society : Book of abstracts
Belgrade : Serbian Genetic Society., 52-52.
https://hdl.handle.net/21.15107/rcub_vinar_12387

Jotić A, Kuveljić J, Kolaković A, Kolić I, Živković M, Jesić S, Stanković A. Toll like receptors 2 and 4 polymorphisms in chronic otitis media. in V Congress of the Serbian Genetic Society : Book of abstracts. 2014;:52-52.
https://hdl.handle.net/21.15107/rcub_vinar_12387 .

Jotić, Ana, Kuveljić, Jovana, Kolaković, Ana, Kolić, Ivana, Živković, Maja, Jesić, Snežana, Stanković, Aleksandra, "Toll like receptors 2 and 4 polymorphisms in chronic otitis media" in V Congress of the Serbian Genetic Society : Book of abstracts (2014):52-52,
https://hdl.handle.net/21.15107/rcub_vinar_12387 .

TY  - CONF
AU  - Kolić, Ivana
AU  - Živković, Maja
AU  - Kuveljić, Jovana
AU  - Jesić, Snežana
AU  - Stanković, Aleksandra
PY  - 2014
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/12388
AB  - Constitutional polymorphisms in the proinflamatory cytokine genes influence the individual cytokine secretion levels, the course and severity of inflammation. Aim of our study was to investigate the association of IL-1β +3953 C/T and IL1-Ra86 bp VNTR gene polymorphisms with the development of chronic otitis media (COM) in 144 patients and 103 controls. Frequencies of the alleles and genotypes of the IL-1Ra gene polymorphism were significantly different between the patients and controls (alleles: p=0.003; genotypes: p=0.0001). Non-carriers of IL-1Ra allele 2 had significatly higher risk for COM occurence (p=0.002; OR=2.98; ±95%CI, 1.68-5.26). This allele is a potential protective genetic marker for COM.
PB  - Belgrade : Serbian Genetic Society
C3  - V Congress of the Serbian Genetic Society : Book of abstracts
T1  - The IL-1β and IL-1Ra gene polymorphisms and chronic inflammation of the middle ear
SP  - 42
EP  - 42
UR  - https://hdl.handle.net/21.15107/rcub_vinar_12388
ER  - 

@conference{
author = "Kolić, Ivana and Živković, Maja and Kuveljić, Jovana and Jesić, Snežana and Stanković, Aleksandra",
year = "2014",
abstract = "Constitutional polymorphisms in the proinflamatory cytokine genes influence the individual cytokine secretion levels, the course and severity of inflammation. Aim of our study was to investigate the association of IL-1β +3953 C/T and IL1-Ra86 bp VNTR gene polymorphisms with the development of chronic otitis media (COM) in 144 patients and 103 controls. Frequencies of the alleles and genotypes of the IL-1Ra gene polymorphism were significantly different between the patients and controls (alleles: p=0.003; genotypes: p=0.0001). Non-carriers of IL-1Ra allele 2 had significatly higher risk for COM occurence (p=0.002; OR=2.98; ±95%CI, 1.68-5.26). This allele is a potential protective genetic marker for COM.",
publisher = "Belgrade : Serbian Genetic Society",
journal = "V Congress of the Serbian Genetic Society : Book of abstracts",
title = "The IL-1β and IL-1Ra gene polymorphisms and chronic inflammation of the middle ear",
pages = "42-42",
url = "https://hdl.handle.net/21.15107/rcub_vinar_12388"
}

Kolić, I., Živković, M., Kuveljić, J., Jesić, S.,& Stanković, A.. (2014). The IL-1β and IL-1Ra gene polymorphisms and chronic inflammation of the middle ear. in V Congress of the Serbian Genetic Society : Book of abstracts
Belgrade : Serbian Genetic Society., 42-42.
https://hdl.handle.net/21.15107/rcub_vinar_12388

Kolić I, Živković M, Kuveljić J, Jesić S, Stanković A. The IL-1β and IL-1Ra gene polymorphisms and chronic inflammation of the middle ear. in V Congress of the Serbian Genetic Society : Book of abstracts. 2014;:42-42.
https://hdl.handle.net/21.15107/rcub_vinar_12388 .

Kolić, Ivana, Živković, Maja, Kuveljić, Jovana, Jesić, Snežana, Stanković, Aleksandra, "The IL-1β and IL-1Ra gene polymorphisms and chronic inflammation of the middle ear" in V Congress of the Serbian Genetic Society : Book of abstracts (2014):42-42,
https://hdl.handle.net/21.15107/rcub_vinar_12388 .