@conference{
author = "Jovanović, M. and Šećerov, Bojana and Bačić, Goran",
year = "2016",
abstract = "We investigated the potential of in vivoelectron paramagnetic resonance (EPR) in assessingchemical reactions that occur during ionizing irradiation and capabilities of two radioprotectors (an antibiotic, anisomycin and a naturally occurring tiol, Gl2011) to enhance survival during irradiation. Radioprotectors selected are supposed to have different modes of action and in vivoEPR was used to assess whether free radical scavenging has arole in their action as radioprotectors. Both compounds exhibited similar and highly efficient radioprotective capabilities according to the 30-days survival test (96% and 87%, respectively after the dose of 6.7 Gy). In vivoEPR showed that free radical scavenging has an important role in the action of GL2011, but not in the case of anisomycin. In conclusion, EPR have unique capabilities in studying free radicals in vivoand can beuseful addition to battery of methods needed to study radioprotectorsin vivo.",
publisher = "Society of Physical Chemists of Serbia",
journal = "Physical chemistry 2016 : 13th international conference on fundamental and applied aspects of physical chemistry",
title = "The potential of in vivo EPR in evaluating free radical reactions in irradiated rats and mechanisms of radioprotection",
pages = "491-494",
url = "https://hdl.handle.net/21.15107/rcub_vinar_9212"
}