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Detection of transforming growth factor-beta 1 in human plasma - A pilot study on breast cancer patients
(Jugoslovenska Medicinska Biohemija, 2001)
There has been much controversy concerning the detection of plasma TGF-beta (1) levels in breast cancer patients. The present study provides preliminary evidence on underestimated plasma TGF-beta (1) levels due to ex vivo ...
Effect of immobilization and cold stress on sympatho-adrenal system in rats exposed to long-term cold
(Jugoslovenska Medicinska Biohemija, 2001)
In the present study we examined changes in plasma levels of catecholamines, corticosterone and adrenomedullary TH gene expression after a short (2 h) and long-term (28 days) cold exposure, as well as in the cold adapted ...
DNA microarrays - A new dimension in molecular oncology
(Jugoslovenska Medicinska Biohemija, 2001)
DNA microarrays or gene chips are methods of performing an enormous number of parallel DNA hybridization experiments. Technically, this approach relies on the orderly attachment of a gene probes on solid surface (the array) ...
Downregulation of c-fos and c-myc expression and apoptosis induction by tiazofurin and 8-Cl-cAMP in human melanoma cells
(Jugoslovenska Medicinska Biohemija, 2001)
Tiazofurin and 8-Cl-cAMP are novel antineoplastic agents that have been shown to be effective against various cancer cells in vitro and in vivo. Through specific mechanisms of action they modulate the cellular signal ...
Toward century of pharmacogenetics: The role of genetic epidemiology with cardiovascular diseases as an example
(Jugoslovenska Medicinska Biohemija, 2001)
Genome research-based medicine is predicted to deliver unprecedented health gains across the entire spectrum of human diseases. The process has already begun and accelerates during the time. The completion of a complex ...