Investigation of Ion Release and Antibacterial Properties of TiN-Cu-Nanocoated Nitinol Archwires
Аутори
Ilić, BojanaPetrović, Božana
Marinković, Jelena
Miletić Vukajlović, Jadranka
Stevanović, Momir
Potočnik, Jelena
Jokanović, Vukoman
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Background: The use of nitinol (NiTi) archwires in orthodontic treatment has increased significantly due to unique mechanical properties. The greatest obstacle for safe orthodontic treatment is chemically or microbiologically induced corrosion, resulting in nickel (Ni) release. The aim of this investigation was to enhance corrosion resistance and introduce antibacterial properties to NiTi archwires by coating them with copper (Cu) doper titanium nitride (TiN-Cu). Methods: NiTi archwires were coated with TiN-Cu using cathodic arc evaporation (CAE) and direct current magnetron sputtering (DC-MS). The morphology of the sample was analyzed via field emission scanning electron microscopy (FESEM) and chemical composition was assessed using energy-dispersive X-ray spectroscopy (EDS), X-ray diffraction (XRD) and Fourier transformed infrared spectroscopy (FTIR). Inductively coupled plasma optical emission spectrometry (ICP-OES) was used to estimate the ion release. The biocompatibility of sampl...es was investigated using 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyl tetrazolium bromide (MTT) assay. Antibacterial activity was tested against Streptococcus mutans and Streptococcus mitis. Results: Physicochemical characterization revealed well-designed coatings with the presence of TiN phase with incorporated Cu. TiN-Cu-nanocoated archwires showed a statistically lower Ni release (p < 0.05). Relative cell viability was the highest in 28-day eluates of TiN-Cu-nanocoated archwires (p < 0.05). The most remarkable decrease in Streptococcus mitis concentrations was observed in the case of TiN-Cu-coated archwires (p < 0.05). Conclusion: Taking into account biocompatibility and antibacterial tests, TiN-Cu-nanocoated archwires may be considered as a good candidate for further clinical investigations
Кључне речи:
antibacterial activity / orthodontic archwires / Streptococcus mutans / nanocoatingsИзвор:
Coatings, 2023, 13, 9, 1587-Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200017 (Универзитет у Београду, Институт за нуклеарне науке Винча, Београд-Винча) (RS-MESTD-inst-2020-200017)
Колекције
Институција/група
VinčaTY - JOUR AU - Ilić, Bojana AU - Petrović, Božana AU - Marinković, Jelena AU - Miletić Vukajlović, Jadranka AU - Stevanović, Momir AU - Potočnik, Jelena AU - Jokanović, Vukoman PY - 2023 UR - https://vinar.vin.bg.ac.rs/handle/123456789/11624 AB - Background: The use of nitinol (NiTi) archwires in orthodontic treatment has increased significantly due to unique mechanical properties. The greatest obstacle for safe orthodontic treatment is chemically or microbiologically induced corrosion, resulting in nickel (Ni) release. The aim of this investigation was to enhance corrosion resistance and introduce antibacterial properties to NiTi archwires by coating them with copper (Cu) doper titanium nitride (TiN-Cu). Methods: NiTi archwires were coated with TiN-Cu using cathodic arc evaporation (CAE) and direct current magnetron sputtering (DC-MS). The morphology of the sample was analyzed via field emission scanning electron microscopy (FESEM) and chemical composition was assessed using energy-dispersive X-ray spectroscopy (EDS), X-ray diffraction (XRD) and Fourier transformed infrared spectroscopy (FTIR). Inductively coupled plasma optical emission spectrometry (ICP-OES) was used to estimate the ion release. The biocompatibility of samples was investigated using 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyl tetrazolium bromide (MTT) assay. Antibacterial activity was tested against Streptococcus mutans and Streptococcus mitis. Results: Physicochemical characterization revealed well-designed coatings with the presence of TiN phase with incorporated Cu. TiN-Cu-nanocoated archwires showed a statistically lower Ni release (p < 0.05). Relative cell viability was the highest in 28-day eluates of TiN-Cu-nanocoated archwires (p < 0.05). The most remarkable decrease in Streptococcus mitis concentrations was observed in the case of TiN-Cu-coated archwires (p < 0.05). Conclusion: Taking into account biocompatibility and antibacterial tests, TiN-Cu-nanocoated archwires may be considered as a good candidate for further clinical investigations T2 - Coatings T1 - Investigation of Ion Release and Antibacterial Properties of TiN-Cu-Nanocoated Nitinol Archwires VL - 13 IS - 9 SP - 1587 DO - 10.3390/coatings13091587 ER -
@article{ author = "Ilić, Bojana and Petrović, Božana and Marinković, Jelena and Miletić Vukajlović, Jadranka and Stevanović, Momir and Potočnik, Jelena and Jokanović, Vukoman", year = "2023", abstract = "Background: The use of nitinol (NiTi) archwires in orthodontic treatment has increased significantly due to unique mechanical properties. The greatest obstacle for safe orthodontic treatment is chemically or microbiologically induced corrosion, resulting in nickel (Ni) release. The aim of this investigation was to enhance corrosion resistance and introduce antibacterial properties to NiTi archwires by coating them with copper (Cu) doper titanium nitride (TiN-Cu). Methods: NiTi archwires were coated with TiN-Cu using cathodic arc evaporation (CAE) and direct current magnetron sputtering (DC-MS). The morphology of the sample was analyzed via field emission scanning electron microscopy (FESEM) and chemical composition was assessed using energy-dispersive X-ray spectroscopy (EDS), X-ray diffraction (XRD) and Fourier transformed infrared spectroscopy (FTIR). Inductively coupled plasma optical emission spectrometry (ICP-OES) was used to estimate the ion release. The biocompatibility of samples was investigated using 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyl tetrazolium bromide (MTT) assay. Antibacterial activity was tested against Streptococcus mutans and Streptococcus mitis. Results: Physicochemical characterization revealed well-designed coatings with the presence of TiN phase with incorporated Cu. TiN-Cu-nanocoated archwires showed a statistically lower Ni release (p < 0.05). Relative cell viability was the highest in 28-day eluates of TiN-Cu-nanocoated archwires (p < 0.05). The most remarkable decrease in Streptococcus mitis concentrations was observed in the case of TiN-Cu-coated archwires (p < 0.05). Conclusion: Taking into account biocompatibility and antibacterial tests, TiN-Cu-nanocoated archwires may be considered as a good candidate for further clinical investigations", journal = "Coatings", title = "Investigation of Ion Release and Antibacterial Properties of TiN-Cu-Nanocoated Nitinol Archwires", volume = "13", number = "9", pages = "1587", doi = "10.3390/coatings13091587" }
Ilić, B., Petrović, B., Marinković, J., Miletić Vukajlović, J., Stevanović, M., Potočnik, J.,& Jokanović, V.. (2023). Investigation of Ion Release and Antibacterial Properties of TiN-Cu-Nanocoated Nitinol Archwires. in Coatings, 13(9), 1587. https://doi.org/10.3390/coatings13091587
Ilić B, Petrović B, Marinković J, Miletić Vukajlović J, Stevanović M, Potočnik J, Jokanović V. Investigation of Ion Release and Antibacterial Properties of TiN-Cu-Nanocoated Nitinol Archwires. in Coatings. 2023;13(9):1587. doi:10.3390/coatings13091587 .
Ilić, Bojana, Petrović, Božana, Marinković, Jelena, Miletić Vukajlović, Jadranka, Stevanović, Momir, Potočnik, Jelena, Jokanović, Vukoman, "Investigation of Ion Release and Antibacterial Properties of TiN-Cu-Nanocoated Nitinol Archwires" in Coatings, 13, no. 9 (2023):1587, https://doi.org/10.3390/coatings13091587 . .