Sensing Platform Based on Carbon Paste Electrode Modified with Bismuth Oxide Nanoparticles and SWCNT for Submicromolar Quantification of Honokiol
Само за регистроване кориснике
2021
Аутори
Knežević, SaraOgnjanović, Miloš
Dojčinović, Biljana
Antić, Bratislav
Vraneš-Đurić, Sanja
Manojlović, Dragan
Stanković, Dalibor M.
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Honokiol is neolignan present in the magnolia bark. It displays versatile pharmacological properties—neuroprotective and anxiolytic effect, anti-cancer activity and antimicrobial effect being the most important. This paper aims to develop a voltammetric non-enzymatic biosensor for honokiol detection, quantification and monitoring in drugs and cosmetic products. The materials used in this study were synthesized and characterized by HR-XRPD, SEM, ATR-FTIR and electrochemical methods. Bi2O3, being a p-type semiconductor, was used as an electrode material. Both its semiconductivity and electrocatalytic properties result from lattice structure defects, which differ on the surface and in the bulk of the bismuth oxide crystal, and therefore are crystal size dependent. The influence of the particle size of Bi2O3 on its electrocatalytic properties was studied, and it was confirmed that Bi2O3 nanoparticles have better overall conductive/resistive and catalytic characteristics than microribbons a...nd that the optimal electrode modification for sensing application was obtained by Bi2O3@SWCNT composite material preparation. Here, we established a sensitive electrochemical sensing platform for honokiol detection based on CP electrode modified with bismuth oxide nanoparticles and SWCNT with the 0.17 μM limit of detection, and linear operating range from 0.1 to 50 μM. The effect of potential interferents on honokiol detection was explored. Obtained results in the interference tests and the real sample analysis suggest that the developed approach is selective, accurate and reproducible. Due to the low detection limit and a wide working range, the proposed sensing platform opens great opportunities for further construction of sensors for honokiol detection and monitoring in the pharmaceutical industry and medicinal chemistry.
Кључне речи:
Modified carbon paste electrode / Natural product / Real sample analysisИзвор:
Food Analytical Methods, 2021Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200168 (Универзитет у Београду, Хемијски факултет) (RS-MESTD-inst-2020-200168)
- EUREKA [E! 13303 MED-BIO-TEST]
DOI: 10.1007/s12161-021-02174-2
ISSN: 1936-9751
WoS: 000718076000001
Scopus: 2-s2.0-85119274870
Колекције
Институција/група
VinčaTY - JOUR AU - Knežević, Sara AU - Ognjanović, Miloš AU - Dojčinović, Biljana AU - Antić, Bratislav AU - Vraneš-Đurić, Sanja AU - Manojlović, Dragan AU - Stanković, Dalibor M. PY - 2021 UR - https://vinar.vin.bg.ac.rs/handle/123456789/10055 AB - Honokiol is neolignan present in the magnolia bark. It displays versatile pharmacological properties—neuroprotective and anxiolytic effect, anti-cancer activity and antimicrobial effect being the most important. This paper aims to develop a voltammetric non-enzymatic biosensor for honokiol detection, quantification and monitoring in drugs and cosmetic products. The materials used in this study were synthesized and characterized by HR-XRPD, SEM, ATR-FTIR and electrochemical methods. Bi2O3, being a p-type semiconductor, was used as an electrode material. Both its semiconductivity and electrocatalytic properties result from lattice structure defects, which differ on the surface and in the bulk of the bismuth oxide crystal, and therefore are crystal size dependent. The influence of the particle size of Bi2O3 on its electrocatalytic properties was studied, and it was confirmed that Bi2O3 nanoparticles have better overall conductive/resistive and catalytic characteristics than microribbons and that the optimal electrode modification for sensing application was obtained by Bi2O3@SWCNT composite material preparation. Here, we established a sensitive electrochemical sensing platform for honokiol detection based on CP electrode modified with bismuth oxide nanoparticles and SWCNT with the 0.17 μM limit of detection, and linear operating range from 0.1 to 50 μM. The effect of potential interferents on honokiol detection was explored. Obtained results in the interference tests and the real sample analysis suggest that the developed approach is selective, accurate and reproducible. Due to the low detection limit and a wide working range, the proposed sensing platform opens great opportunities for further construction of sensors for honokiol detection and monitoring in the pharmaceutical industry and medicinal chemistry. T2 - Food Analytical Methods T1 - Sensing Platform Based on Carbon Paste Electrode Modified with Bismuth Oxide Nanoparticles and SWCNT for Submicromolar Quantification of Honokiol DO - 10.1007/s12161-021-02174-2 ER -
@article{ author = "Knežević, Sara and Ognjanović, Miloš and Dojčinović, Biljana and Antić, Bratislav and Vraneš-Đurić, Sanja and Manojlović, Dragan and Stanković, Dalibor M.", year = "2021", abstract = "Honokiol is neolignan present in the magnolia bark. It displays versatile pharmacological properties—neuroprotective and anxiolytic effect, anti-cancer activity and antimicrobial effect being the most important. This paper aims to develop a voltammetric non-enzymatic biosensor for honokiol detection, quantification and monitoring in drugs and cosmetic products. The materials used in this study were synthesized and characterized by HR-XRPD, SEM, ATR-FTIR and electrochemical methods. Bi2O3, being a p-type semiconductor, was used as an electrode material. Both its semiconductivity and electrocatalytic properties result from lattice structure defects, which differ on the surface and in the bulk of the bismuth oxide crystal, and therefore are crystal size dependent. The influence of the particle size of Bi2O3 on its electrocatalytic properties was studied, and it was confirmed that Bi2O3 nanoparticles have better overall conductive/resistive and catalytic characteristics than microribbons and that the optimal electrode modification for sensing application was obtained by Bi2O3@SWCNT composite material preparation. Here, we established a sensitive electrochemical sensing platform for honokiol detection based on CP electrode modified with bismuth oxide nanoparticles and SWCNT with the 0.17 μM limit of detection, and linear operating range from 0.1 to 50 μM. The effect of potential interferents on honokiol detection was explored. Obtained results in the interference tests and the real sample analysis suggest that the developed approach is selective, accurate and reproducible. Due to the low detection limit and a wide working range, the proposed sensing platform opens great opportunities for further construction of sensors for honokiol detection and monitoring in the pharmaceutical industry and medicinal chemistry.", journal = "Food Analytical Methods", title = "Sensing Platform Based on Carbon Paste Electrode Modified with Bismuth Oxide Nanoparticles and SWCNT for Submicromolar Quantification of Honokiol", doi = "10.1007/s12161-021-02174-2" }
Knežević, S., Ognjanović, M., Dojčinović, B., Antić, B., Vraneš-Đurić, S., Manojlović, D.,& Stanković, D. M.. (2021). Sensing Platform Based on Carbon Paste Electrode Modified with Bismuth Oxide Nanoparticles and SWCNT for Submicromolar Quantification of Honokiol. in Food Analytical Methods. https://doi.org/10.1007/s12161-021-02174-2
Knežević S, Ognjanović M, Dojčinović B, Antić B, Vraneš-Đurić S, Manojlović D, Stanković DM. Sensing Platform Based on Carbon Paste Electrode Modified with Bismuth Oxide Nanoparticles and SWCNT for Submicromolar Quantification of Honokiol. in Food Analytical Methods. 2021;. doi:10.1007/s12161-021-02174-2 .
Knežević, Sara, Ognjanović, Miloš, Dojčinović, Biljana, Antić, Bratislav, Vraneš-Đurić, Sanja, Manojlović, Dragan, Stanković, Dalibor M., "Sensing Platform Based on Carbon Paste Electrode Modified with Bismuth Oxide Nanoparticles and SWCNT for Submicromolar Quantification of Honokiol" in Food Analytical Methods (2021), https://doi.org/10.1007/s12161-021-02174-2 . .