TY  - JOUR
AU  - Jasnic, N.
AU  - Đorđević, Jelena D.
AU  - Djurasevic, S.
AU  - Lakic, I.
AU  - Vujovic, P.
AU  - Spasojević, Nataša
AU  - Cvijic, G.
PY  - 2012
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/5003
AB  - The response of hypothalamo-pituitary-adrenocortical (HPA) axis to different stressors depends on numerous stimulatory and inhibitory signals gathering from various parts of the brain to the hypothalamic nuclei. The present study was aimed at determining whether catecholamines (CA) and vasopressin (VP) play the role in the specific regulation of adrenocorticotropic hormone (ACTH) secretion under the influence of thermal stressors, cold (+4 degrees C) and heat (+38 degrees C), applied acutely for 1 h or repeatedly during 7 and 14 day (1 h daily). The results showed that following acute exposure to those stressors, hypothalamic dopamine (DA), noradrenaline (NA) and adrenaline (ADR) concentrations were significantly decreased as compared to non stressed controls. The prolonged exposure to either of the two stressors left hypothalamic CA concentration unaffected. The amount of pituitary VP significantly increased only under the influence of acute heat stress. Prolonged exposure to both stressors induced significant decrease in the pituitary VP content. Unlike the heat, the cold-caused changes in circulating VP did not follow those in the pituitary. The applied stressors significantly increased the amount of the pituitary V1b receptor (V1bR) mainly present at the surface of corticotrophs, depending on both duration of exposure and nature of stressor. Additionally, both cold and heat specifically induced an increase in blood ACTH. In conclusion, this studys results suggest that the role of VP in the regulation of the ACTH secretion in response to cold and heat depends on the type of stressor, whereas the role of the CA depends on the manner of exposure. (C) 2012 Elsevier Ltd. All rights reserved.
T2  - Journal of Thermal Biology
T1  - Specific regulation of ACTH secretion under the influence of low and high ambient temperature-The role of catecholamines and vasopressin
VL  - 37
IS  - 7
SP  - 469
EP  - 474
DO  - 10.1016/j.jtherbio.2012.04.003
ER  - 

@article{
author = "Jasnic, N. and Đorđević, Jelena D. and Djurasevic, S. and Lakic, I. and Vujovic, P. and Spasojević, Nataša and Cvijic, G.",
year = "2012",
abstract = "The response of hypothalamo-pituitary-adrenocortical (HPA) axis to different stressors depends on numerous stimulatory and inhibitory signals gathering from various parts of the brain to the hypothalamic nuclei. The present study was aimed at determining whether catecholamines (CA) and vasopressin (VP) play the role in the specific regulation of adrenocorticotropic hormone (ACTH) secretion under the influence of thermal stressors, cold (+4 degrees C) and heat (+38 degrees C), applied acutely for 1 h or repeatedly during 7 and 14 day (1 h daily). The results showed that following acute exposure to those stressors, hypothalamic dopamine (DA), noradrenaline (NA) and adrenaline (ADR) concentrations were significantly decreased as compared to non stressed controls. The prolonged exposure to either of the two stressors left hypothalamic CA concentration unaffected. The amount of pituitary VP significantly increased only under the influence of acute heat stress. Prolonged exposure to both stressors induced significant decrease in the pituitary VP content. Unlike the heat, the cold-caused changes in circulating VP did not follow those in the pituitary. The applied stressors significantly increased the amount of the pituitary V1b receptor (V1bR) mainly present at the surface of corticotrophs, depending on both duration of exposure and nature of stressor. Additionally, both cold and heat specifically induced an increase in blood ACTH. In conclusion, this studys results suggest that the role of VP in the regulation of the ACTH secretion in response to cold and heat depends on the type of stressor, whereas the role of the CA depends on the manner of exposure. (C) 2012 Elsevier Ltd. All rights reserved.",
journal = "Journal of Thermal Biology",
title = "Specific regulation of ACTH secretion under the influence of low and high ambient temperature-The role of catecholamines and vasopressin",
volume = "37",
number = "7",
pages = "469-474",
doi = "10.1016/j.jtherbio.2012.04.003"
}

Jasnic, N., Đorđević, J. D., Djurasevic, S., Lakic, I., Vujovic, P., Spasojević, N.,& Cvijic, G.. (2012). Specific regulation of ACTH secretion under the influence of low and high ambient temperature-The role of catecholamines and vasopressin. in Journal of Thermal Biology, 37(7), 469-474.
https://doi.org/10.1016/j.jtherbio.2012.04.003

Jasnic N, Đorđević JD, Djurasevic S, Lakic I, Vujovic P, Spasojević N, Cvijic G. Specific regulation of ACTH secretion under the influence of low and high ambient temperature-The role of catecholamines and vasopressin. in Journal of Thermal Biology. 2012;37(7):469-474.
doi:10.1016/j.jtherbio.2012.04.003 .

Jasnic, N., Đorđević, Jelena D., Djurasevic, S., Lakic, I., Vujovic, P., Spasojević, Nataša, Cvijic, G., "Specific regulation of ACTH secretion under the influence of low and high ambient temperature-The role of catecholamines and vasopressin" in Journal of Thermal Biology, 37, no. 7 (2012):469-474,
https://doi.org/10.1016/j.jtherbio.2012.04.003 . .

TY  - JOUR
AU  - Đorđević, Jelena D.
AU  - Jasnic, N.
AU  - Vujovic, P.
AU  - Lakic, I.
AU  - Djurasevic, S.
AU  - Gavrilović, Ljubica
AU  - Cvijic, G.
PY  - 2012
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/4647
AB  - The heart is an organ especially sensitive to the sympathetic overstimulation and therefore to the influence of stressors and hypertension. The aim of the present study was to investigate the effect of two distinct types of stressors, acute immobilization (2 h) and chronic isolation stress (21 days), as well as their combined effect on the activity of monoamine oxidase (MAO), superoxide dismutase, catalase (CAT) and the ascorbic acid (AA) content in the heart of normotensive and spontaneously hypertensive rats (SHR). The results obtained show that in basal conditions heart MAO and CAT activity (p LT 0.05), as well as AA concentration (p LT 0.01) were higher in SHR than in normotensive ones. The acute immobilization significantly decreased heart MAO activity in both examined strains (p LT 0.01). On the other hand, chronic isolation, separately or in combination with immobilization, did not affect this enzyme, in the heart of either hypertensive or normotensive rats, which was associated with the reduced antioxidative protection (p LT 0.01, p LT 0.05).
T2  - Journal of Animal Physiology and Animal Nutrition
T1  - Distinct and combined effects of acute immobilization and chronic isolation stress on MAO activity and antioxidative protection in the heart of normotensive and spontaneously hypertensive rats
VL  - 96
IS  - 1
SP  - 58
EP  - 65
DO  - 10.1111/j.1439-0396.2010.01122.x
ER  - 

@article{
author = "Đorđević, Jelena D. and Jasnic, N. and Vujovic, P. and Lakic, I. and Djurasevic, S. and Gavrilović, Ljubica and Cvijic, G.",
year = "2012",
abstract = "The heart is an organ especially sensitive to the sympathetic overstimulation and therefore to the influence of stressors and hypertension. The aim of the present study was to investigate the effect of two distinct types of stressors, acute immobilization (2 h) and chronic isolation stress (21 days), as well as their combined effect on the activity of monoamine oxidase (MAO), superoxide dismutase, catalase (CAT) and the ascorbic acid (AA) content in the heart of normotensive and spontaneously hypertensive rats (SHR). The results obtained show that in basal conditions heart MAO and CAT activity (p LT 0.05), as well as AA concentration (p LT 0.01) were higher in SHR than in normotensive ones. The acute immobilization significantly decreased heart MAO activity in both examined strains (p LT 0.01). On the other hand, chronic isolation, separately or in combination with immobilization, did not affect this enzyme, in the heart of either hypertensive or normotensive rats, which was associated with the reduced antioxidative protection (p LT 0.01, p LT 0.05).",
journal = "Journal of Animal Physiology and Animal Nutrition",
title = "Distinct and combined effects of acute immobilization and chronic isolation stress on MAO activity and antioxidative protection in the heart of normotensive and spontaneously hypertensive rats",
volume = "96",
number = "1",
pages = "58-65",
doi = "10.1111/j.1439-0396.2010.01122.x"
}

Đorđević, J. D., Jasnic, N., Vujovic, P., Lakic, I., Djurasevic, S., Gavrilović, L.,& Cvijic, G.. (2012). Distinct and combined effects of acute immobilization and chronic isolation stress on MAO activity and antioxidative protection in the heart of normotensive and spontaneously hypertensive rats. in Journal of Animal Physiology and Animal Nutrition, 96(1), 58-65.
https://doi.org/10.1111/j.1439-0396.2010.01122.x

Đorđević JD, Jasnic N, Vujovic P, Lakic I, Djurasevic S, Gavrilović L, Cvijic G. Distinct and combined effects of acute immobilization and chronic isolation stress on MAO activity and antioxidative protection in the heart of normotensive and spontaneously hypertensive rats. in Journal of Animal Physiology and Animal Nutrition. 2012;96(1):58-65.
doi:10.1111/j.1439-0396.2010.01122.x .

Đorđević, Jelena D., Jasnic, N., Vujovic, P., Lakic, I., Djurasevic, S., Gavrilović, Ljubica, Cvijic, G., "Distinct and combined effects of acute immobilization and chronic isolation stress on MAO activity and antioxidative protection in the heart of normotensive and spontaneously hypertensive rats" in Journal of Animal Physiology and Animal Nutrition, 96, no. 1 (2012):58-65,
https://doi.org/10.1111/j.1439-0396.2010.01122.x . .