Addition of a Fluoride-containing Radiopacifier Improves Micromechanical and Biological Characteristics of Modified Calcium Silicate Cements
Нема приказа
Аутори
Antonijević, ĐorđeJesthke, Anke
Čolović, Božana M.
Milovanović, Petar
Jevremovic, Danimir
Kisić, Danilo
vom Scheidt, Annika
Hahn, Michael
Amling, Michael
Jokanović, Vukoman R.
Busse, Bjoern
Đurić, Marija
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Introduction: Calcium silicate cements (CSCs) with the addition of nanohydroxyapatite and calcium carbonate play a critical role in dental applications. To further improve their properties, particularly radiopacity and biointeractivity, the fluoride-containing radiopacifier ytterbium trifluoride (YbF3) was added to their composition, and biological and mechanical characteristics were evaluated. Methods: YbF3 was added to 3 different CSCs: cement I (CSC + calcium carbonate), cement II (CSC + nanohydroxyapatite), and Portland cement. Material characterization encompassed measurements of pH, calcium, ytterbium, and fluoride ion release; radiopacity; setting time; porosity; microindentation properties; wettability; and Fourier transform infrared spectroscopic, x-ray diffraction, and scanning electron microscopic analyses. Osteoblast- and osteoclast-like cells were grown on the materials surface to evaluate their adherence. Results: The addition of calcium carbonate, nanohydroxyapatite, and... 30 wt% of YbF3 improved radiopacity and the setting time of experimental cements. The pH values did not differ among the groups. The greatest ytterbium and fluoride releases occurred in the Portland cement + YbF3 group. Combined x-ray diffraction and Fourier transform infrared spectroscopic analysis showed the presence of calcium hydroxide and calcium silicate hydrates. In addition, the presence of calcium ytterbium fluoride and ytterbium oxide proved that YbF3 reacted with cement compounds. Wettability of cement I + YbF3 was superior to other formulations, but its porosity and microindentation properties were weaker than in the Portland cement + YbF3 mixture. Cement II + YbF3 presented micromechanical indentation and porosity characteristics similar to the Portland-based cement formulation. Osteoclast- and osteoblast-like cells adhered to the cements surfaces without alteration of the cell structural integrity. Conclusions: YbF3-containing CSCs with nanostructured hydroxyapatite and calcium carbonate are well suited for dental application.
Кључне речи:
Bioactivity / calcium silicate / dental cement / fluoride / micro computed tomography / osteoblasts / reference point indentationИзвор:
Journal of Endodontics, 2015, 41, 12, 2050-2057Финансирање / пројекти:
- Функционални, функционализовани и усавршени нано материјали (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-45005)
- Синтеза и биолошка испитивања нових миметика или деривата одабраних цитотоксичних лактона, антитуморског агенса тиазофурина и природних нафтних киселина (RS-MESTD-Basic Research (BR or ON)-172006)
- German Academic Exchange Service (DAAD), South-East-Europe Cooperation of the University Medical Center Hamburg-Eppendorf
DOI: 10.1016/j.joen.2015.09.008
ISSN: 0099-2399; 1878-3554
PubMed: 26518217
WoS: 000366146200018
Scopus: 2-s2.0-84951335480
Колекције
Институција/група
VinčaTY - JOUR AU - Antonijević, Đorđe AU - Jesthke, Anke AU - Čolović, Božana M. AU - Milovanović, Petar AU - Jevremovic, Danimir AU - Kisić, Danilo AU - vom Scheidt, Annika AU - Hahn, Michael AU - Amling, Michael AU - Jokanović, Vukoman R. AU - Busse, Bjoern AU - Đurić, Marija PY - 2015 UR - https://vinar.vin.bg.ac.rs/handle/123456789/847 AB - Introduction: Calcium silicate cements (CSCs) with the addition of nanohydroxyapatite and calcium carbonate play a critical role in dental applications. To further improve their properties, particularly radiopacity and biointeractivity, the fluoride-containing radiopacifier ytterbium trifluoride (YbF3) was added to their composition, and biological and mechanical characteristics were evaluated. Methods: YbF3 was added to 3 different CSCs: cement I (CSC + calcium carbonate), cement II (CSC + nanohydroxyapatite), and Portland cement. Material characterization encompassed measurements of pH, calcium, ytterbium, and fluoride ion release; radiopacity; setting time; porosity; microindentation properties; wettability; and Fourier transform infrared spectroscopic, x-ray diffraction, and scanning electron microscopic analyses. Osteoblast- and osteoclast-like cells were grown on the materials surface to evaluate their adherence. Results: The addition of calcium carbonate, nanohydroxyapatite, and 30 wt% of YbF3 improved radiopacity and the setting time of experimental cements. The pH values did not differ among the groups. The greatest ytterbium and fluoride releases occurred in the Portland cement + YbF3 group. Combined x-ray diffraction and Fourier transform infrared spectroscopic analysis showed the presence of calcium hydroxide and calcium silicate hydrates. In addition, the presence of calcium ytterbium fluoride and ytterbium oxide proved that YbF3 reacted with cement compounds. Wettability of cement I + YbF3 was superior to other formulations, but its porosity and microindentation properties were weaker than in the Portland cement + YbF3 mixture. Cement II + YbF3 presented micromechanical indentation and porosity characteristics similar to the Portland-based cement formulation. Osteoclast- and osteoblast-like cells adhered to the cements surfaces without alteration of the cell structural integrity. Conclusions: YbF3-containing CSCs with nanostructured hydroxyapatite and calcium carbonate are well suited for dental application. T2 - Journal of Endodontics T1 - Addition of a Fluoride-containing Radiopacifier Improves Micromechanical and Biological Characteristics of Modified Calcium Silicate Cements VL - 41 IS - 12 SP - 2050 EP - 2057 DO - 10.1016/j.joen.2015.09.008 ER -
@article{ author = "Antonijević, Đorđe and Jesthke, Anke and Čolović, Božana M. and Milovanović, Petar and Jevremovic, Danimir and Kisić, Danilo and vom Scheidt, Annika and Hahn, Michael and Amling, Michael and Jokanović, Vukoman R. and Busse, Bjoern and Đurić, Marija", year = "2015", abstract = "Introduction: Calcium silicate cements (CSCs) with the addition of nanohydroxyapatite and calcium carbonate play a critical role in dental applications. To further improve their properties, particularly radiopacity and biointeractivity, the fluoride-containing radiopacifier ytterbium trifluoride (YbF3) was added to their composition, and biological and mechanical characteristics were evaluated. Methods: YbF3 was added to 3 different CSCs: cement I (CSC + calcium carbonate), cement II (CSC + nanohydroxyapatite), and Portland cement. Material characterization encompassed measurements of pH, calcium, ytterbium, and fluoride ion release; radiopacity; setting time; porosity; microindentation properties; wettability; and Fourier transform infrared spectroscopic, x-ray diffraction, and scanning electron microscopic analyses. Osteoblast- and osteoclast-like cells were grown on the materials surface to evaluate their adherence. Results: The addition of calcium carbonate, nanohydroxyapatite, and 30 wt% of YbF3 improved radiopacity and the setting time of experimental cements. The pH values did not differ among the groups. The greatest ytterbium and fluoride releases occurred in the Portland cement + YbF3 group. Combined x-ray diffraction and Fourier transform infrared spectroscopic analysis showed the presence of calcium hydroxide and calcium silicate hydrates. In addition, the presence of calcium ytterbium fluoride and ytterbium oxide proved that YbF3 reacted with cement compounds. Wettability of cement I + YbF3 was superior to other formulations, but its porosity and microindentation properties were weaker than in the Portland cement + YbF3 mixture. Cement II + YbF3 presented micromechanical indentation and porosity characteristics similar to the Portland-based cement formulation. Osteoclast- and osteoblast-like cells adhered to the cements surfaces without alteration of the cell structural integrity. Conclusions: YbF3-containing CSCs with nanostructured hydroxyapatite and calcium carbonate are well suited for dental application.", journal = "Journal of Endodontics", title = "Addition of a Fluoride-containing Radiopacifier Improves Micromechanical and Biological Characteristics of Modified Calcium Silicate Cements", volume = "41", number = "12", pages = "2050-2057", doi = "10.1016/j.joen.2015.09.008" }
Antonijević, Đ., Jesthke, A., Čolović, B. M., Milovanović, P., Jevremovic, D., Kisić, D., vom Scheidt, A., Hahn, M., Amling, M., Jokanović, V. R., Busse, B.,& Đurić, M.. (2015). Addition of a Fluoride-containing Radiopacifier Improves Micromechanical and Biological Characteristics of Modified Calcium Silicate Cements. in Journal of Endodontics, 41(12), 2050-2057. https://doi.org/10.1016/j.joen.2015.09.008
Antonijević Đ, Jesthke A, Čolović BM, Milovanović P, Jevremovic D, Kisić D, vom Scheidt A, Hahn M, Amling M, Jokanović VR, Busse B, Đurić M. Addition of a Fluoride-containing Radiopacifier Improves Micromechanical and Biological Characteristics of Modified Calcium Silicate Cements. in Journal of Endodontics. 2015;41(12):2050-2057. doi:10.1016/j.joen.2015.09.008 .
Antonijević, Đorđe, Jesthke, Anke, Čolović, Božana M., Milovanović, Petar, Jevremovic, Danimir, Kisić, Danilo, vom Scheidt, Annika, Hahn, Michael, Amling, Michael, Jokanović, Vukoman R., Busse, Bjoern, Đurić, Marija, "Addition of a Fluoride-containing Radiopacifier Improves Micromechanical and Biological Characteristics of Modified Calcium Silicate Cements" in Journal of Endodontics, 41, no. 12 (2015):2050-2057, https://doi.org/10.1016/j.joen.2015.09.008 . .