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Link Between Oxidative Stress and Acute Brain Ischemia
dc.creator | Radak, Đorđe J. | |
dc.creator | Resanović, Ivana | |
dc.creator | Isenović, Esma R. | |
dc.date.accessioned | 2018-03-01T15:22:20Z | |
dc.date.available | 2018-03-01T15:22:20Z | |
dc.date.issued | 2014 | |
dc.identifier.issn | 0003-3197 | |
dc.identifier.issn | 1940-1574 | |
dc.identifier.uri | https://vinar.vin.bg.ac.rs/handle/123456789/79 | |
dc.description.abstract | The pathogenesis of acute brain ischemia (ABI) is highly complex and involves multiple mechanisms including free radical generation. Imbalance between the cellular production of free radicals and the ability of cells to defend against them is referred to as oxidative stress. Oxidative stress is one of the mechanisms contributing to neuronal damage, potentially induced through the ABI. Through interactions with a large number of molecules, reactive oxygen species may irreversibly destroy or alter the function of the cellular lipids, proteins, and nucleic acids and initiate cell signaling pathways after cerebral ischemia. Future investigations should focus on the understanding of oxidative stress mechanisms and neuro-protection in order to discover new treatment targets. | en |
dc.relation | info:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/41002/RS// | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173033/RS// | |
dc.rights | restrictedAccess | en |
dc.source | Angiology | en |
dc.subject | oxidative stress | en |
dc.subject | free radicals | en |
dc.subject | acute brain ischemia | en |
dc.subject | stroke | en |
dc.title | Link Between Oxidative Stress and Acute Brain Ischemia | en |
dc.type | article | en |
dc.rights.license | ARR | |
dcterms.abstract | Ресановић Ивана; Радак, Дјордје; Исеновић Есма; | |
dc.citation.volume | 65 | |
dc.citation.issue | 8 | |
dc.citation.spage | 667 | |
dc.citation.epage | 676 | |
dc.identifier.wos | 000340715700003 | |
dc.identifier.doi | 10.1177/0003319713506516 | |
dc.citation.rank | M22 | |
dc.identifier.pmid | 24132856 | |
dc.type.version | publishedVersion | |
dc.identifier.scopus | 2-s2.0-84905923659 |
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080 - Laboratorija za radiobiologiju i molekularnu genetiku
Department of Radiobiology and Molecular Genetics