Vitamin D and Dysfunctional Adipose Tissue in Obesity
Само за регистроване кориснике
2015
Аутори
Stokić, EditaKupusinac, Aleksandar
Tomic-Naglic, Dragana
Smiljenic, Dragana
Kovacev-Zavisic, Branka
Srdić-Galić, Biljana
Soskić, Sanja S.
Isenović, Esma R.
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Vitamin D deficiency and dysfunctional adipose tissue are involved in the development of cardiometabolic disturbances (eg, hypertension, insulin resistance, type 2 diabetes mellitus, obesity, and dyslipidemia). We evaluated the relation between vitamin D and adipocytokines derived from adipose tissue. We studied 50 obese individuals who were classified into different subgroups according to medians of observed anthropometric parameters (body mass index, body fat percentage, waist circumference, and trunk fat mass). There was a negative correlation between vitamin D level and leptin and resistin (r = -.61, P LT .01), while a positive association with adiponectin concentrations was found (r = .7, P LT .001). Trend estimation showed that increase in vitamin D level is accompanied by intensive increase in adiponectin concentrations (growth coefficient: 12.13). In conclusion, a positive trend was established between vitamin D and the protective adipocytokine adiponectin. The clinical relevan...ce of this relationship needs to be investigated in larger studies.
Кључне речи:
vitamin D / dysfunctional adipose tissue / obesity / adipocytokineИзвор:
Angiology, 2015, 66, 7, 613-618Финансирање / пројекти:
- Репрезентације логичких структура и формалних језика и њихове примене у рачунарству (RS-MESTD-Basic Research (BR or ON)-174026)
- Развој нових информационо-комуникационих технологија, коришћењем напредних математичких метода, са применама у медицини, телекомуникацијама, енергетици, заштитити националне баштине и образовању (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-44006)
- Хормонска регулација експресије и активности азот оксид синтазе и натријум-калијумове пумпе у експерименталним моделима инсулинске резистенције, дијабетеса и кардиоваскуларних поремећаја (RS-MESTD-Basic Research (BR or ON)-173033)
DOI: 10.1177/0003319714543512
ISSN: 0003-3197; 1940-1574
PubMed: 25053676
WoS: 000358577600004
Scopus: 2-s2.0-84937917766
Колекције
Институција/група
VinčaTY - JOUR AU - Stokić, Edita AU - Kupusinac, Aleksandar AU - Tomic-Naglic, Dragana AU - Smiljenic, Dragana AU - Kovacev-Zavisic, Branka AU - Srdić-Galić, Biljana AU - Soskić, Sanja S. AU - Isenović, Esma R. PY - 2015 UR - https://vinar.vin.bg.ac.rs/handle/123456789/673 AB - Vitamin D deficiency and dysfunctional adipose tissue are involved in the development of cardiometabolic disturbances (eg, hypertension, insulin resistance, type 2 diabetes mellitus, obesity, and dyslipidemia). We evaluated the relation between vitamin D and adipocytokines derived from adipose tissue. We studied 50 obese individuals who were classified into different subgroups according to medians of observed anthropometric parameters (body mass index, body fat percentage, waist circumference, and trunk fat mass). There was a negative correlation between vitamin D level and leptin and resistin (r = -.61, P LT .01), while a positive association with adiponectin concentrations was found (r = .7, P LT .001). Trend estimation showed that increase in vitamin D level is accompanied by intensive increase in adiponectin concentrations (growth coefficient: 12.13). In conclusion, a positive trend was established between vitamin D and the protective adipocytokine adiponectin. The clinical relevance of this relationship needs to be investigated in larger studies. T2 - Angiology T1 - Vitamin D and Dysfunctional Adipose Tissue in Obesity VL - 66 IS - 7 SP - 613 EP - 618 DO - 10.1177/0003319714543512 ER -
@article{ author = "Stokić, Edita and Kupusinac, Aleksandar and Tomic-Naglic, Dragana and Smiljenic, Dragana and Kovacev-Zavisic, Branka and Srdić-Galić, Biljana and Soskić, Sanja S. and Isenović, Esma R.", year = "2015", abstract = "Vitamin D deficiency and dysfunctional adipose tissue are involved in the development of cardiometabolic disturbances (eg, hypertension, insulin resistance, type 2 diabetes mellitus, obesity, and dyslipidemia). We evaluated the relation between vitamin D and adipocytokines derived from adipose tissue. We studied 50 obese individuals who were classified into different subgroups according to medians of observed anthropometric parameters (body mass index, body fat percentage, waist circumference, and trunk fat mass). There was a negative correlation between vitamin D level and leptin and resistin (r = -.61, P LT .01), while a positive association with adiponectin concentrations was found (r = .7, P LT .001). Trend estimation showed that increase in vitamin D level is accompanied by intensive increase in adiponectin concentrations (growth coefficient: 12.13). In conclusion, a positive trend was established between vitamin D and the protective adipocytokine adiponectin. The clinical relevance of this relationship needs to be investigated in larger studies.", journal = "Angiology", title = "Vitamin D and Dysfunctional Adipose Tissue in Obesity", volume = "66", number = "7", pages = "613-618", doi = "10.1177/0003319714543512" }
Stokić, E., Kupusinac, A., Tomic-Naglic, D., Smiljenic, D., Kovacev-Zavisic, B., Srdić-Galić, B., Soskić, S. S.,& Isenović, E. R.. (2015). Vitamin D and Dysfunctional Adipose Tissue in Obesity. in Angiology, 66(7), 613-618. https://doi.org/10.1177/0003319714543512
Stokić E, Kupusinac A, Tomic-Naglic D, Smiljenic D, Kovacev-Zavisic B, Srdić-Galić B, Soskić SS, Isenović ER. Vitamin D and Dysfunctional Adipose Tissue in Obesity. in Angiology. 2015;66(7):613-618. doi:10.1177/0003319714543512 .
Stokić, Edita, Kupusinac, Aleksandar, Tomic-Naglic, Dragana, Smiljenic, Dragana, Kovacev-Zavisic, Branka, Srdić-Galić, Biljana, Soskić, Sanja S., Isenović, Esma R., "Vitamin D and Dysfunctional Adipose Tissue in Obesity" in Angiology, 66, no. 7 (2015):613-618, https://doi.org/10.1177/0003319714543512 . .