Absorbed Dose Uncertainty Estimation for Proton Therapy
Apstrakt
Successful radiotherapy treatment depends on the absorbed dose evaluation and the possibility to define metrological characteristics of the therapy beam. Radiotherapy requires tumor dose delivery with expanded uncertainty less than +/- 5 %. It is particularly important to reduce uncertainty during therapy beam calibration as well as to apply all necessary ionization chamber correction factors. Absorbed dose to water was determined using ionometric method. Calibration was performed in reference cobalt beam. Combined standard uncertainty of the calculated absorbed dose to water in 65 MeV proton beam was +/- 1.97% while the obtained expanded uncertainty of absorbed dose for the same beam quality was +/- 5.02%. The uncertainty estimation method has been developed within the project TESLA.
Ključne reči:
protons / absorbed dose / therapy / uncertaintyIzvor:
Nuclear technology and radiation protection, 2012, 27, 3, 297-304Finansiranje / projekti:
- Fizika i hemija sa jonskim snopovima (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-45006)
DOI: 10.2298/NTRP1203297S
ISSN: 1451-3994
WoS: 000309481800012
Scopus: 2-s2.0-84867904053
Kolekcije
Institucija/grupa
VinčaTY - JOUR AU - Spasić-Jokić, Vesna AU - Dobrosavljević, Aleksandar S. AU - Beličev, Petar PY - 2012 UR - https://vinar.vin.bg.ac.rs/handle/123456789/5070 AB - Successful radiotherapy treatment depends on the absorbed dose evaluation and the possibility to define metrological characteristics of the therapy beam. Radiotherapy requires tumor dose delivery with expanded uncertainty less than +/- 5 %. It is particularly important to reduce uncertainty during therapy beam calibration as well as to apply all necessary ionization chamber correction factors. Absorbed dose to water was determined using ionometric method. Calibration was performed in reference cobalt beam. Combined standard uncertainty of the calculated absorbed dose to water in 65 MeV proton beam was +/- 1.97% while the obtained expanded uncertainty of absorbed dose for the same beam quality was +/- 5.02%. The uncertainty estimation method has been developed within the project TESLA. T2 - Nuclear technology and radiation protection T1 - Absorbed Dose Uncertainty Estimation for Proton Therapy VL - 27 IS - 3 SP - 297 EP - 304 DO - 10.2298/NTRP1203297S ER -
@article{ author = "Spasić-Jokić, Vesna and Dobrosavljević, Aleksandar S. and Beličev, Petar", year = "2012", abstract = "Successful radiotherapy treatment depends on the absorbed dose evaluation and the possibility to define metrological characteristics of the therapy beam. Radiotherapy requires tumor dose delivery with expanded uncertainty less than +/- 5 %. It is particularly important to reduce uncertainty during therapy beam calibration as well as to apply all necessary ionization chamber correction factors. Absorbed dose to water was determined using ionometric method. Calibration was performed in reference cobalt beam. Combined standard uncertainty of the calculated absorbed dose to water in 65 MeV proton beam was +/- 1.97% while the obtained expanded uncertainty of absorbed dose for the same beam quality was +/- 5.02%. The uncertainty estimation method has been developed within the project TESLA.", journal = "Nuclear technology and radiation protection", title = "Absorbed Dose Uncertainty Estimation for Proton Therapy", volume = "27", number = "3", pages = "297-304", doi = "10.2298/NTRP1203297S" }
Spasić-Jokić, V., Dobrosavljević, A. S.,& Beličev, P.. (2012). Absorbed Dose Uncertainty Estimation for Proton Therapy. in Nuclear technology and radiation protection, 27(3), 297-304. https://doi.org/10.2298/NTRP1203297S
Spasić-Jokić V, Dobrosavljević AS, Beličev P. Absorbed Dose Uncertainty Estimation for Proton Therapy. in Nuclear technology and radiation protection. 2012;27(3):297-304. doi:10.2298/NTRP1203297S .
Spasić-Jokić, Vesna, Dobrosavljević, Aleksandar S., Beličev, Petar, "Absorbed Dose Uncertainty Estimation for Proton Therapy" in Nuclear technology and radiation protection, 27, no. 3 (2012):297-304, https://doi.org/10.2298/NTRP1203297S . .