Obesity and Vitamin D Deficiency: Trends to Promote a More Proatherogenic Cardiometabolic Risk Profile
Само за регистроване кориснике
2015
Аутори
Stokić, EditaKupusinac, Aleksandar
Tomic-Naglic, Dragana
Zavisic, Branka Kovacev
Mitrovic, Milena
Smiljenic, Dragana
Soskić, Sanja S.
Isenović, Esma R.
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Vitamin D deficiency is associated with cardiometabolic risk factors (eg, hypertension, insulin resistance, type 2 diabetes mellitus, obesity, and dyslipidemia). We studied 50 obese patients (body mass index [BMI]: 43.5 +/- 9.2 kg/m(2)) and 36 normal weight participants (BMI: 22.6 +/- 1.9 kg/m(2)). The prevalence of vitamin D deficiency (25-hydroxyvitamin D, 25(OH)D LT 50 nmol/L) was 88% among obese patients and 31% among nonobese individuals; 25(OH)D levels were lower in the obese group (27.3 +/- 13.7 vs 64.6 +/- 21.3 nmol/L; P LT .001). There was a negative correlation between vitamin D level and anthropometric indicators of obesity: BMI (r = -0.64; P LT .001), waist circumference (r = -0.59; P LT .001), and body fat percentage (r = -0.64; P LT .001) as well as with fasting plasma insulin (r = -0.35; P LT .001) and homeostasis model assessment of insulin resistance (r = -0.35; P LT .001). In conclusion, we observed a higher prevalence of vitamin D deficiency among obese participants ...and this was associated with a proatherogenic cardiometabolic risk profile.
Кључне речи:
vitamin D deficiency / obesity / cardiometabolic riskИзвор:
Angiology, 2015, 66, 3, 237-243Финансирање / пројекти:
- Репрезентације логичких структура и формалних језика и њихове примене у рачунарству (RS-MESTD-Basic Research (BR or ON)-174026)
- Развој нових информационо-комуникационих технологија, коришћењем напредних математичких метода, са применама у медицини, телекомуникацијама, енергетици, заштитити националне баштине и образовању (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-44006)
- Хормонска регулација експресије и активности азот оксид синтазе и натријум-калијумове пумпе у експерименталним моделима инсулинске резистенције, дијабетеса и кардиоваскуларних поремећаја (RS-MESTD-Basic Research (BR or ON)-173033)
DOI: 10.1177/0003319714528569
ISSN: 0003-3197; 1940-1574
PubMed: 24658164
WoS: 000349321200007
Scopus: 2-s2.0-84900801924
Колекције
Институција/група
VinčaTY - JOUR AU - Stokić, Edita AU - Kupusinac, Aleksandar AU - Tomic-Naglic, Dragana AU - Zavisic, Branka Kovacev AU - Mitrovic, Milena AU - Smiljenic, Dragana AU - Soskić, Sanja S. AU - Isenović, Esma R. PY - 2015 UR - https://vinar.vin.bg.ac.rs/handle/123456789/395 AB - Vitamin D deficiency is associated with cardiometabolic risk factors (eg, hypertension, insulin resistance, type 2 diabetes mellitus, obesity, and dyslipidemia). We studied 50 obese patients (body mass index [BMI]: 43.5 +/- 9.2 kg/m(2)) and 36 normal weight participants (BMI: 22.6 +/- 1.9 kg/m(2)). The prevalence of vitamin D deficiency (25-hydroxyvitamin D, 25(OH)D LT 50 nmol/L) was 88% among obese patients and 31% among nonobese individuals; 25(OH)D levels were lower in the obese group (27.3 +/- 13.7 vs 64.6 +/- 21.3 nmol/L; P LT .001). There was a negative correlation between vitamin D level and anthropometric indicators of obesity: BMI (r = -0.64; P LT .001), waist circumference (r = -0.59; P LT .001), and body fat percentage (r = -0.64; P LT .001) as well as with fasting plasma insulin (r = -0.35; P LT .001) and homeostasis model assessment of insulin resistance (r = -0.35; P LT .001). In conclusion, we observed a higher prevalence of vitamin D deficiency among obese participants and this was associated with a proatherogenic cardiometabolic risk profile. T2 - Angiology T1 - Obesity and Vitamin D Deficiency: Trends to Promote a More Proatherogenic Cardiometabolic Risk Profile VL - 66 IS - 3 SP - 237 EP - 243 DO - 10.1177/0003319714528569 ER -
@article{ author = "Stokić, Edita and Kupusinac, Aleksandar and Tomic-Naglic, Dragana and Zavisic, Branka Kovacev and Mitrovic, Milena and Smiljenic, Dragana and Soskić, Sanja S. and Isenović, Esma R.", year = "2015", abstract = "Vitamin D deficiency is associated with cardiometabolic risk factors (eg, hypertension, insulin resistance, type 2 diabetes mellitus, obesity, and dyslipidemia). We studied 50 obese patients (body mass index [BMI]: 43.5 +/- 9.2 kg/m(2)) and 36 normal weight participants (BMI: 22.6 +/- 1.9 kg/m(2)). The prevalence of vitamin D deficiency (25-hydroxyvitamin D, 25(OH)D LT 50 nmol/L) was 88% among obese patients and 31% among nonobese individuals; 25(OH)D levels were lower in the obese group (27.3 +/- 13.7 vs 64.6 +/- 21.3 nmol/L; P LT .001). There was a negative correlation between vitamin D level and anthropometric indicators of obesity: BMI (r = -0.64; P LT .001), waist circumference (r = -0.59; P LT .001), and body fat percentage (r = -0.64; P LT .001) as well as with fasting plasma insulin (r = -0.35; P LT .001) and homeostasis model assessment of insulin resistance (r = -0.35; P LT .001). In conclusion, we observed a higher prevalence of vitamin D deficiency among obese participants and this was associated with a proatherogenic cardiometabolic risk profile.", journal = "Angiology", title = "Obesity and Vitamin D Deficiency: Trends to Promote a More Proatherogenic Cardiometabolic Risk Profile", volume = "66", number = "3", pages = "237-243", doi = "10.1177/0003319714528569" }
Stokić, E., Kupusinac, A., Tomic-Naglic, D., Zavisic, B. K., Mitrovic, M., Smiljenic, D., Soskić, S. S.,& Isenović, E. R.. (2015). Obesity and Vitamin D Deficiency: Trends to Promote a More Proatherogenic Cardiometabolic Risk Profile. in Angiology, 66(3), 237-243. https://doi.org/10.1177/0003319714528569
Stokić E, Kupusinac A, Tomic-Naglic D, Zavisic BK, Mitrovic M, Smiljenic D, Soskić SS, Isenović ER. Obesity and Vitamin D Deficiency: Trends to Promote a More Proatherogenic Cardiometabolic Risk Profile. in Angiology. 2015;66(3):237-243. doi:10.1177/0003319714528569 .
Stokić, Edita, Kupusinac, Aleksandar, Tomic-Naglic, Dragana, Zavisic, Branka Kovacev, Mitrovic, Milena, Smiljenic, Dragana, Soskić, Sanja S., Isenović, Esma R., "Obesity and Vitamin D Deficiency: Trends to Promote a More Proatherogenic Cardiometabolic Risk Profile" in Angiology, 66, no. 3 (2015):237-243, https://doi.org/10.1177/0003319714528569 . .