Selective indicator reaction for kinetic determination of traces of manganese(II), ribavirin and tiazofurin
Апстракт
In this work it was established that, in the presence of ammonium carbonate, traces of manganese(II) catalyse the oxidation of Nile Blue A by hydrogen peroxide, which enables its: kinetic determination in the concentration range from 6.6 to 65.9 ng cm(-3), the detection limit being 8.0 x 10(-2) ng cm(-3). Antiviral/antitumour substances modify the catalytic activity of manganese (TT): 1-beta -D-ribofuranosyl-1,2,4-triazole-3-carboxamide, ribavirin, increases the catalytic effect of manganese(II), while 2-beta -D-ribofuranosyl-thiazole-4-carboxamide, tiazofurin, acts as an inhibitor. On the basis of these effects, a kinetic method for determining ribavirin concentrations from 0.5 x 10(-1) to 4.0 x 10(-1) mug cm(-3) and tiazofurin concentrations from 0.3 to 2.6 mug cm(-3) is proposed. The kinetics of the indicator reaction were studied ill the presence of the substances examined, the kinetic equations established, and the constants of the corresponding reaction rates calculated. The effe...ct of temperature on these reactions was also investigated. The method was applied to the determination of manganese(II) in mineral water and ribavirin in pharmaceutical preparations.
Кључне речи:
manganese(II) / kinetic determination / 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide, ribavirin / 2-beta-D-ribofuranosyl-thiazole-4-carboxamide / Nile Blue A oxidation / tiazofurinИзвор:
Microchimica Acta, 2000, 135, 3-4, 173-178
DOI: 10.1007/s006040070007
ISSN: 0026-3672
WoS: 000165829900007
Scopus: 2-s2.0-0034530978
Колекције
Институција/група
VinčaTY - JOUR AU - Milovanović, GA AU - Čakar, Mira M. AU - Vučić, Nevenka B. AU - Jokanović, Milan PY - 2000 UR - https://vinar.vin.bg.ac.rs/handle/123456789/2397 AB - In this work it was established that, in the presence of ammonium carbonate, traces of manganese(II) catalyse the oxidation of Nile Blue A by hydrogen peroxide, which enables its: kinetic determination in the concentration range from 6.6 to 65.9 ng cm(-3), the detection limit being 8.0 x 10(-2) ng cm(-3). Antiviral/antitumour substances modify the catalytic activity of manganese (TT): 1-beta -D-ribofuranosyl-1,2,4-triazole-3-carboxamide, ribavirin, increases the catalytic effect of manganese(II), while 2-beta -D-ribofuranosyl-thiazole-4-carboxamide, tiazofurin, acts as an inhibitor. On the basis of these effects, a kinetic method for determining ribavirin concentrations from 0.5 x 10(-1) to 4.0 x 10(-1) mug cm(-3) and tiazofurin concentrations from 0.3 to 2.6 mug cm(-3) is proposed. The kinetics of the indicator reaction were studied ill the presence of the substances examined, the kinetic equations established, and the constants of the corresponding reaction rates calculated. The effect of temperature on these reactions was also investigated. The method was applied to the determination of manganese(II) in mineral water and ribavirin in pharmaceutical preparations. T2 - Microchimica Acta T1 - Selective indicator reaction for kinetic determination of traces of manganese(II), ribavirin and tiazofurin VL - 135 IS - 3-4 SP - 173 EP - 178 DO - 10.1007/s006040070007 ER -
@article{ author = "Milovanović, GA and Čakar, Mira M. and Vučić, Nevenka B. and Jokanović, Milan", year = "2000", abstract = "In this work it was established that, in the presence of ammonium carbonate, traces of manganese(II) catalyse the oxidation of Nile Blue A by hydrogen peroxide, which enables its: kinetic determination in the concentration range from 6.6 to 65.9 ng cm(-3), the detection limit being 8.0 x 10(-2) ng cm(-3). Antiviral/antitumour substances modify the catalytic activity of manganese (TT): 1-beta -D-ribofuranosyl-1,2,4-triazole-3-carboxamide, ribavirin, increases the catalytic effect of manganese(II), while 2-beta -D-ribofuranosyl-thiazole-4-carboxamide, tiazofurin, acts as an inhibitor. On the basis of these effects, a kinetic method for determining ribavirin concentrations from 0.5 x 10(-1) to 4.0 x 10(-1) mug cm(-3) and tiazofurin concentrations from 0.3 to 2.6 mug cm(-3) is proposed. The kinetics of the indicator reaction were studied ill the presence of the substances examined, the kinetic equations established, and the constants of the corresponding reaction rates calculated. The effect of temperature on these reactions was also investigated. The method was applied to the determination of manganese(II) in mineral water and ribavirin in pharmaceutical preparations.", journal = "Microchimica Acta", title = "Selective indicator reaction for kinetic determination of traces of manganese(II), ribavirin and tiazofurin", volume = "135", number = "3-4", pages = "173-178", doi = "10.1007/s006040070007" }
Milovanović, G., Čakar, M. M., Vučić, N. B.,& Jokanović, M.. (2000). Selective indicator reaction for kinetic determination of traces of manganese(II), ribavirin and tiazofurin. in Microchimica Acta, 135(3-4), 173-178. https://doi.org/10.1007/s006040070007
Milovanović G, Čakar MM, Vučić NB, Jokanović M. Selective indicator reaction for kinetic determination of traces of manganese(II), ribavirin and tiazofurin. in Microchimica Acta. 2000;135(3-4):173-178. doi:10.1007/s006040070007 .
Milovanović, GA, Čakar, Mira M., Vučić, Nevenka B., Jokanović, Milan, "Selective indicator reaction for kinetic determination of traces of manganese(II), ribavirin and tiazofurin" in Microchimica Acta, 135, no. 3-4 (2000):173-178, https://doi.org/10.1007/s006040070007 . .