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Voxel model of a rabbit: assessment of absorbed doses in organs after CT examination performed by two different protocols

Authorized Users Only
2021
Authors
Mitrović, Marko
Ciraj-Bjelac, Olivera
Jovanović, Z.
Krstić, N.
Nikezić, Dragoslav
Krstić, D.
Živković, M.
Lazarević-Macanović, Mirjana
Article (Published version)
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Abstract
The objective of this work was to assess absorbed doses in organs and tissues of a rabbit, following computed tomography (CT) examinations, using a dedicated 3D voxel model. Absorbed doses in relevant organs were calculated using the MCNP5 Monte Carlo software. Calculations were perfomed for two standard CT protocols, using tube voltages of 110 kVp and 130 kVp. Absorbed doses were calculated in 11 organs and tissues, i.e., skin, bones, brain, muscles, heart, lungs, liver, spleen, kidney, testicles, and fat tissue. The doses ranged from 15.3 to 28.3 mGy, and from 40.2 to 74.3 mGy, in the two investigated protocols. The organs that received the highest dose were bones and kidneys. In contrast, brain and spleen were organs that received the smallest doses. Doses in organs which are stretched along the body did not change significantly with distance. On the other hand, doses in organs which are localized in the body showed maximums and minimums. Using the voxel model, it is possible to cal...culate the dose distribution in the rabbit’s body after CT scans, and study the potential biological effects of CT doses in certain organs. The voxel model presented in this work can be used to calculated doses in all radiation experiments in which rabbits are used as experimental animals.

Keywords:
Absorbed dose / CT / MCNP5 / Rabbit / Voxel phantom
Source:
Radiation and Environmental Biophysics, 2021, 60, 4, 631-638
Funding / projects:
  • Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 200122 (University of Kragujevac, Faculty of Science) (RS-200122)
  • Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 200143 (University of Belgrade, Faculty of Veterinary Medicine) (RS-200143)

DOI: 10.1007/s00411-021-00941-7

ISSN: 1432-2099

WoS: 000692971200002

Scopus: 2-s2.0-85114373465
[ Google Scholar ]
1
1
URI
https://vinar.vin.bg.ac.rs/handle/123456789/9913
Collections
  • Radovi istraživača
Institution/Community
Vinča
TY  - JOUR
AU  - Mitrović, Marko
AU  - Ciraj-Bjelac, Olivera
AU  - Jovanović, Z.
AU  - Krstić, N.
AU  - Nikezić, Dragoslav
AU  - Krstić, D.
AU  - Živković, M.
AU  - Lazarević-Macanović, Mirjana
PY  - 2021
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/9913
AB  - The objective of this work was to assess absorbed doses in organs and tissues of a rabbit, following computed tomography (CT) examinations, using a dedicated 3D voxel model. Absorbed doses in relevant organs were calculated using the MCNP5 Monte Carlo software. Calculations were perfomed for two standard CT protocols, using tube voltages of 110 kVp and 130 kVp. Absorbed doses were calculated in 11 organs and tissues, i.e., skin, bones, brain, muscles, heart, lungs, liver, spleen, kidney, testicles, and fat tissue. The doses ranged from 15.3 to 28.3 mGy, and from 40.2 to 74.3 mGy, in the two investigated protocols. The organs that received the highest dose were bones and kidneys. In contrast, brain and spleen were organs that received the smallest doses. Doses in organs which are stretched along the body did not change significantly with distance. On the other hand, doses in organs which are localized in the body showed maximums and minimums. Using the voxel model, it is possible to calculate the dose distribution in the rabbit’s body after CT scans, and study the potential biological effects of CT doses in certain organs. The voxel model presented in this work can be used to calculated doses in all radiation experiments in which rabbits are used as experimental animals.
T2  - Radiation and Environmental Biophysics
T1  - Voxel model of a rabbit: assessment of absorbed doses in organs after CT examination performed by two different protocols
VL  - 60
IS  - 4
SP  - 631
EP  - 638
DO  - 10.1007/s00411-021-00941-7
ER  - 
@article{
author = "Mitrović, Marko and Ciraj-Bjelac, Olivera and Jovanović, Z. and Krstić, N. and Nikezić, Dragoslav and Krstić, D. and Živković, M. and Lazarević-Macanović, Mirjana",
year = "2021",
abstract = "The objective of this work was to assess absorbed doses in organs and tissues of a rabbit, following computed tomography (CT) examinations, using a dedicated 3D voxel model. Absorbed doses in relevant organs were calculated using the MCNP5 Monte Carlo software. Calculations were perfomed for two standard CT protocols, using tube voltages of 110 kVp and 130 kVp. Absorbed doses were calculated in 11 organs and tissues, i.e., skin, bones, brain, muscles, heart, lungs, liver, spleen, kidney, testicles, and fat tissue. The doses ranged from 15.3 to 28.3 mGy, and from 40.2 to 74.3 mGy, in the two investigated protocols. The organs that received the highest dose were bones and kidneys. In contrast, brain and spleen were organs that received the smallest doses. Doses in organs which are stretched along the body did not change significantly with distance. On the other hand, doses in organs which are localized in the body showed maximums and minimums. Using the voxel model, it is possible to calculate the dose distribution in the rabbit’s body after CT scans, and study the potential biological effects of CT doses in certain organs. The voxel model presented in this work can be used to calculated doses in all radiation experiments in which rabbits are used as experimental animals.",
journal = "Radiation and Environmental Biophysics",
title = "Voxel model of a rabbit: assessment of absorbed doses in organs after CT examination performed by two different protocols",
volume = "60",
number = "4",
pages = "631-638",
doi = "10.1007/s00411-021-00941-7"
}
Mitrović, M., Ciraj-Bjelac, O., Jovanović, Z., Krstić, N., Nikezić, D., Krstić, D., Živković, M.,& Lazarević-Macanović, M.. (2021). Voxel model of a rabbit: assessment of absorbed doses in organs after CT examination performed by two different protocols. in Radiation and Environmental Biophysics, 60(4), 631-638.
https://doi.org/10.1007/s00411-021-00941-7
Mitrović M, Ciraj-Bjelac O, Jovanović Z, Krstić N, Nikezić D, Krstić D, Živković M, Lazarević-Macanović M. Voxel model of a rabbit: assessment of absorbed doses in organs after CT examination performed by two different protocols. in Radiation and Environmental Biophysics. 2021;60(4):631-638.
doi:10.1007/s00411-021-00941-7 .
Mitrović, Marko, Ciraj-Bjelac, Olivera, Jovanović, Z., Krstić, N., Nikezić, Dragoslav, Krstić, D., Živković, M., Lazarević-Macanović, Mirjana, "Voxel model of a rabbit: assessment of absorbed doses in organs after CT examination performed by two different protocols" in Radiation and Environmental Biophysics, 60, no. 4 (2021):631-638,
https://doi.org/10.1007/s00411-021-00941-7 . .

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