On water synthesis of the novel 2-oxo-1,2,3,4-tetrahydropyrimidines
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2021
Authors
Milović, EmilijaJanković, Nenad Ž.

Bogdanović, Goran A.

Petronijević, Jelena

Joksimović, Nenad

Article (Published version)

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A simple on water approach for the synthesis of novel tetrahydropyrimidine (THPM) derivatives has been developed under a green and sustainable fashion. For the first time, a deuterated Biginelli's hybrid was synthesized. Novel THPMs are suitable for further derivatization and could be an excellent toolkit for lead-oriented synthesis and/or cross-coupling reactions. (C) 2020 Elsevier Ltd. All rights reserved.
Keywords:
biginelli reaction / Biginelli reaction / derivatives / Isotopic labeling / On water / Pyrimidines / tricksSource:
Tetrahedron, 2021, 78, 131790-Funding / projects:
DOI: 10.1016/j.tet.2020.131790
ISSN: 0040-4020
WoS: 000599956100009
Scopus: 2-s2.0-85096842593
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VinčaTY - JOUR AU - Milović, Emilija AU - Janković, Nenad Ž. AU - Bogdanović, Goran A. AU - Petronijević, Jelena AU - Joksimović, Nenad PY - 2021 UR - https://vinar.vin.bg.ac.rs/handle/123456789/9754 AB - A simple on water approach for the synthesis of novel tetrahydropyrimidine (THPM) derivatives has been developed under a green and sustainable fashion. For the first time, a deuterated Biginelli's hybrid was synthesized. Novel THPMs are suitable for further derivatization and could be an excellent toolkit for lead-oriented synthesis and/or cross-coupling reactions. (C) 2020 Elsevier Ltd. All rights reserved. T2 - Tetrahedron T1 - On water synthesis of the novel 2-oxo-1,2,3,4-tetrahydropyrimidines VL - 78 SP - 131790 DO - 10.1016/j.tet.2020.131790 ER -
@article{ author = "Milović, Emilija and Janković, Nenad Ž. and Bogdanović, Goran A. and Petronijević, Jelena and Joksimović, Nenad", year = "2021", abstract = "A simple on water approach for the synthesis of novel tetrahydropyrimidine (THPM) derivatives has been developed under a green and sustainable fashion. For the first time, a deuterated Biginelli's hybrid was synthesized. Novel THPMs are suitable for further derivatization and could be an excellent toolkit for lead-oriented synthesis and/or cross-coupling reactions. (C) 2020 Elsevier Ltd. All rights reserved.", journal = "Tetrahedron", title = "On water synthesis of the novel 2-oxo-1,2,3,4-tetrahydropyrimidines", volume = "78", pages = "131790", doi = "10.1016/j.tet.2020.131790" }
Milović, E., Janković, N. Ž., Bogdanović, G. A., Petronijević, J.,& Joksimović, N.. (2021). On water synthesis of the novel 2-oxo-1,2,3,4-tetrahydropyrimidines. in Tetrahedron, 78, 131790. https://doi.org/10.1016/j.tet.2020.131790
Milović E, Janković NŽ, Bogdanović GA, Petronijević J, Joksimović N. On water synthesis of the novel 2-oxo-1,2,3,4-tetrahydropyrimidines. in Tetrahedron. 2021;78:131790. doi:10.1016/j.tet.2020.131790 .
Milović, Emilija, Janković, Nenad Ž., Bogdanović, Goran A., Petronijević, Jelena, Joksimović, Nenad, "On water synthesis of the novel 2-oxo-1,2,3,4-tetrahydropyrimidines" in Tetrahedron, 78 (2021):131790, https://doi.org/10.1016/j.tet.2020.131790 . .