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dc.creatorLazić, Vesna M.
dc.creatorŽivković, Ljiljana
dc.creatorSredojević, Dušan
dc.creatorFernandes, Margarida M.
dc.creatorLanceros-Mendez, Senentxu
dc.creatorAhrenkiel, Scott Phillip
dc.creatorNedeljković, Jovan
dc.date.accessioned2021-09-23T09:45:05Z
dc.date.available2021-09-23T09:45:05Z
dc.date.issued2020
dc.identifier.issn0743-7463
dc.identifier.urihttps://vinar.vin.bg.ac.rs/handle/123456789/9613
dc.description.abstractCerium dioxide (CeO2) finds applications in areas such as corrosion protection, solar cells, or catalysis, finding increasing applications in biomedicine. This work reports on surface-modified CeO2 particles in order to tune their applicability in the biomedical field. Stable aqueous CeO2 sol, consisting of 3-4 nm in size crystallites, was synthesized using forced hydrolysis. The coordination of catecholate-type of ligands (catechol, caffeic acid, tiron, and dopamine) to the surface-Ce atoms is followed with the appearance of absorption in the visible spectral range as a consequence of interfacial charge-transfer complex formation. The spectroscopic observations are complemented with the density functional theory calculations using a cluster model. The synthesized samples were characterized by X-ray diffraction analysis, transmission electron microscopy, and nitrogen adsorption-desorption isotherms. The ζ-potential measurements indicated that the stability of CeO2 sol is preserved upon surface modification. The pristine CeO2 nanoparticles (NPs) are nontoxic against pre-osteoblast cells in the entire studied concentration range (up to 1.5 mM). Hybrid CeO2 NPs, capped with dopamine or caffeic acid, display toxic behavior for concentrations ≥0.17 and 1.5 mM, respectively. On the other hand, surface-modified CeO2 NPs with catechol and tiron promote the proliferation of pre-osteoblast cells. Copyright © 2020 American Chemical Society.en
dc.relationBilateral project Portugese-Serbia [337-00-00227/2019-09/14]
dc.relationPortuguese Foundation for Science and Technology [ UID/FIS/04650/2020]
dc.relationPortuguese Foundation for Science and Technology [SFRH/BPD/121464/2016]
dc.relationMinistry of Education, Science and Technological Development of the Republic of Serbia
dc.rightsrestrictedAccess
dc.sourceLangmuir
dc.subjectdopamine
dc.subjectmechanism
dc.subjectantioxidans
dc.subjectmodified tio2 nanoparticles
dc.subjectoxide nanoparticles
dc.subjectdna-damage
dc.subjectnanoceria
dc.subjectcharge
dc.subjectcytotoxicity
dc.titleTuning properties of cerium dioxide nanoparticles by surface modification with catecholate-type of ligandsen
dc.typearticleen
dc.rights.licenseARR
dcterms.abstractЛазић, Весна М.; Ланцерос-Мендез, Сенентxу; Фернандес, Маргарида М.; Aхренкиел, Пхиллип С.; Живковић, Љиљана С.; Средојевић, Душан; Недељковић, Јован М.;
dc.citation.volume36
dc.citation.issue33
dc.citation.spage9738
dc.citation.epage9746
dc.identifier.wos000566338500011
dc.identifier.doi10.1021/acs.langmuir.0c01163
dc.identifier.pmid32787065
dc.type.versionpublishedVersion
dc.identifier.scopus2-s2.0-85089922337


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