Tuning properties of cerium dioxide nanoparticles by surface modification with catecholate-type of ligands
Само за регистроване кориснике
2020
Аутори
Lazić, Vesna M.Živković, Ljiljana
Sredojević, Dušan
Fernandes, Margarida M.
Lanceros-Mendez, Senentxu
Ahrenkiel, Scott Phillip
Nedeljković, Jovan
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Cerium dioxide (CeO2) finds applications in areas such as corrosion protection, solar cells, or catalysis, finding increasing applications in biomedicine. This work reports on surface-modified CeO2 particles in order to tune their applicability in the biomedical field. Stable aqueous CeO2 sol, consisting of 3-4 nm in size crystallites, was synthesized using forced hydrolysis. The coordination of catecholate-type of ligands (catechol, caffeic acid, tiron, and dopamine) to the surface-Ce atoms is followed with the appearance of absorption in the visible spectral range as a consequence of interfacial charge-transfer complex formation. The spectroscopic observations are complemented with the density functional theory calculations using a cluster model. The synthesized samples were characterized by X-ray diffraction analysis, transmission electron microscopy, and nitrogen adsorption-desorption isotherms. The ζ-potential measurements indicated that the stability of CeO2 sol is preserved upon... surface modification. The pristine CeO2 nanoparticles (NPs) are nontoxic against pre-osteoblast cells in the entire studied concentration range (up to 1.5 mM). Hybrid CeO2 NPs, capped with dopamine or caffeic acid, display toxic behavior for concentrations ≥0.17 and 1.5 mM, respectively. On the other hand, surface-modified CeO2 NPs with catechol and tiron promote the proliferation of pre-osteoblast cells. Copyright © 2020 American Chemical Society.
Кључне речи:
dopamine / mechanism / antioxidans / modified tio2 nanoparticles / oxide nanoparticles / dna-damage / nanoceria / charge / cytotoxicityИзвор:
Langmuir, 2020, 36, 33, 9738-9746Финансирање / пројекти:
- Bilateral project Portugese-Serbia [337-00-00227/2019-09/14]
- Portuguese Foundation for Science and Technology [ UID/FIS/04650/2020]
- Portuguese Foundation for Science and Technology [SFRH/BPD/121464/2016]
- Ministry of Education, Science and Technological Development of the Republic of Serbia
DOI: 10.1021/acs.langmuir.0c01163
ISSN: 0743-7463
PubMed: 32787065
WoS: 000566338500011
Scopus: 2-s2.0-85089922337
Колекције
Институција/група
VinčaTY - JOUR AU - Lazić, Vesna M. AU - Živković, Ljiljana AU - Sredojević, Dušan AU - Fernandes, Margarida M. AU - Lanceros-Mendez, Senentxu AU - Ahrenkiel, Scott Phillip AU - Nedeljković, Jovan PY - 2020 UR - https://vinar.vin.bg.ac.rs/handle/123456789/9613 AB - Cerium dioxide (CeO2) finds applications in areas such as corrosion protection, solar cells, or catalysis, finding increasing applications in biomedicine. This work reports on surface-modified CeO2 particles in order to tune their applicability in the biomedical field. Stable aqueous CeO2 sol, consisting of 3-4 nm in size crystallites, was synthesized using forced hydrolysis. The coordination of catecholate-type of ligands (catechol, caffeic acid, tiron, and dopamine) to the surface-Ce atoms is followed with the appearance of absorption in the visible spectral range as a consequence of interfacial charge-transfer complex formation. The spectroscopic observations are complemented with the density functional theory calculations using a cluster model. The synthesized samples were characterized by X-ray diffraction analysis, transmission electron microscopy, and nitrogen adsorption-desorption isotherms. The ζ-potential measurements indicated that the stability of CeO2 sol is preserved upon surface modification. The pristine CeO2 nanoparticles (NPs) are nontoxic against pre-osteoblast cells in the entire studied concentration range (up to 1.5 mM). Hybrid CeO2 NPs, capped with dopamine or caffeic acid, display toxic behavior for concentrations ≥0.17 and 1.5 mM, respectively. On the other hand, surface-modified CeO2 NPs with catechol and tiron promote the proliferation of pre-osteoblast cells. Copyright © 2020 American Chemical Society. T2 - Langmuir T1 - Tuning properties of cerium dioxide nanoparticles by surface modification with catecholate-type of ligands VL - 36 IS - 33 SP - 9738 EP - 9746 DO - 10.1021/acs.langmuir.0c01163 ER -
@article{ author = "Lazić, Vesna M. and Živković, Ljiljana and Sredojević, Dušan and Fernandes, Margarida M. and Lanceros-Mendez, Senentxu and Ahrenkiel, Scott Phillip and Nedeljković, Jovan", year = "2020", abstract = "Cerium dioxide (CeO2) finds applications in areas such as corrosion protection, solar cells, or catalysis, finding increasing applications in biomedicine. This work reports on surface-modified CeO2 particles in order to tune their applicability in the biomedical field. Stable aqueous CeO2 sol, consisting of 3-4 nm in size crystallites, was synthesized using forced hydrolysis. The coordination of catecholate-type of ligands (catechol, caffeic acid, tiron, and dopamine) to the surface-Ce atoms is followed with the appearance of absorption in the visible spectral range as a consequence of interfacial charge-transfer complex formation. The spectroscopic observations are complemented with the density functional theory calculations using a cluster model. The synthesized samples were characterized by X-ray diffraction analysis, transmission electron microscopy, and nitrogen adsorption-desorption isotherms. The ζ-potential measurements indicated that the stability of CeO2 sol is preserved upon surface modification. The pristine CeO2 nanoparticles (NPs) are nontoxic against pre-osteoblast cells in the entire studied concentration range (up to 1.5 mM). Hybrid CeO2 NPs, capped with dopamine or caffeic acid, display toxic behavior for concentrations ≥0.17 and 1.5 mM, respectively. On the other hand, surface-modified CeO2 NPs with catechol and tiron promote the proliferation of pre-osteoblast cells. Copyright © 2020 American Chemical Society.", journal = "Langmuir", title = "Tuning properties of cerium dioxide nanoparticles by surface modification with catecholate-type of ligands", volume = "36", number = "33", pages = "9738-9746", doi = "10.1021/acs.langmuir.0c01163" }
Lazić, V. M., Živković, L., Sredojević, D., Fernandes, M. M., Lanceros-Mendez, S., Ahrenkiel, S. P.,& Nedeljković, J.. (2020). Tuning properties of cerium dioxide nanoparticles by surface modification with catecholate-type of ligands. in Langmuir, 36(33), 9738-9746. https://doi.org/10.1021/acs.langmuir.0c01163
Lazić VM, Živković L, Sredojević D, Fernandes MM, Lanceros-Mendez S, Ahrenkiel SP, Nedeljković J. Tuning properties of cerium dioxide nanoparticles by surface modification with catecholate-type of ligands. in Langmuir. 2020;36(33):9738-9746. doi:10.1021/acs.langmuir.0c01163 .
Lazić, Vesna M., Živković, Ljiljana, Sredojević, Dušan, Fernandes, Margarida M., Lanceros-Mendez, Senentxu, Ahrenkiel, Scott Phillip, Nedeljković, Jovan, "Tuning properties of cerium dioxide nanoparticles by surface modification with catecholate-type of ligands" in Langmuir, 36, no. 33 (2020):9738-9746, https://doi.org/10.1021/acs.langmuir.0c01163 . .