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dc.creatorBožović, Ana M.
dc.creatorMandušić, Vesna
dc.creatorTodorović, Lidija
dc.creatorKrajnović, Milena M.
dc.date.accessioned2021-09-13T12:27:32Z
dc.date.available2021-09-13T12:27:32Z
dc.date.issued2021
dc.identifier.issn1422-0067
dc.identifier.urihttps://vinar.vin.bg.ac.rs/handle/123456789/9560
dc.description.abstractThe discovery of the Estrogen Receptor Beta (ERβ) in 1996 opened new perspectives in the diagnostics and therapy of different types of cancer. Here, we present a review of the present research knowledge about its role in endocrine-related cancers: breast, prostate, and thyroid, and colorectal cancers. We also discuss the reasons for the controversy of its role in carcinogenesis and why it is still not in use as a biomarker in clinical practice. Given that the diagnostics and therapy would benefit from the introduction of new biomarkers, we suggest ways to overcome the contradictions in elucidating the role of ERβ.en
dc.language.isoen
dc.relationinfo:eu-repo/grantAgreement/MESTD/inst-2020/200017/RS//
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.sourceInternational Journal of Molecular Sciences
dc.subjectBiomarkeren
dc.subjectCarcinogenesisen
dc.subjectEndocrine-related cancersen
dc.subjectEstrogen Receptor Betaen
dc.subjectIsoformsen
dc.subjectMetastasesen
dc.subjectMethylationen
dc.subjectPromotersen
dc.subjectTumor-suppressoren
dc.titleEstrogen Receptor Beta: The Promising Biomarker and Potential Target in Metastasesen
dc.typearticleen
dc.rights.licenseBY
dcterms.abstractМандушић, Весна; Божовић, Aна; Крајновић, Милена; Тодоровић, Лидија;
dc.rights.holder© 2021 The Author(s)
dc.citation.volume22
dc.citation.issue4
dc.citation.spage1656
dc.identifier.wos000623881500001
dc.identifier.doi10.3390/ijms22041656
dc.identifier.pmid33562134
dc.description.otherSpecial Issue "Biomarkers in Hematological and Oncological Malignancies: Identification, Validation and Involvement in Molecular Pathways"
dc.type.versionpublishedVersion
dc.identifier.scopus2-s2.0-85100504125
dc.identifier.fulltexthttps://vinar.vin.bg.ac.rs/bitstream/id/24443/ijms-22-01656-v2.pdf


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