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TY - JOUR
AU - Joksić, Gordana
AU - Radak, Đorđe J.
AU - Sudar-Milovanović, Emina
AU - Obradović, Milan M.
AU - Radovanović, Jelena V.
AU - Isenović, Esma R.
PY - 2021
UR - https://vinar.vin.bg.ac.rs/handle/123456789/9407
AB - Background: Gentiana lutea (GL), commonly known as yellow gentian, bitter root, and bit-terwort, belongs to family Gentianaceae. GL belongs to genus Gentiana, which is a rich natural source of iridoids, secoiridoids, xantones, flavonoids, triterpenoids, and carbohydrates. Medicinal plants from Gentiana species have anti-oxidant, anti-inflammatory, anti-mitogenic, anti-proliferative, and lipid-lowering effects, as well as a cardioprotective, hypotensive, vasodilator and anti-platelet activities. Objective: We reviewed the recent literature related to the effects of Gentiana species, and their active components on vascular diseases. Methods: Data used for this review were obtained by searching the electronic database [PUB-MED/MEDLINE 1973-February 2020]. The primary data search terms of interest were: Gentiana lutea, Gentienacea family, phytochemistry, vascular diseases, treatment of vascular diseases, anti-oxidant, anti-inflammatory, anti-atherogenic. Conclusion: Gentiana species and their constituents affect many different factors related to vascular disease development and progression. Therefore, Gentiana-based therapeutics represent potentially use-ful drugs for the management of vascular diseases. © 2021 Bentham Science Publishers.
T2 - Current Vascular Pharmacology
T1 - Effects of Gentiana lutea Root on Vascular Diseases
VL - 19
IS - 4
SP - 359
EP - 369
DO - 10.2174/1570161118666200529111314
ER -
@article{
author = "Joksić, Gordana and Radak, Đorđe J. and Sudar-Milovanović, Emina and Obradović, Milan M. and Radovanović, Jelena V. and Isenović, Esma R.",
year = "2021",
abstract = "Background: Gentiana lutea (GL), commonly known as yellow gentian, bitter root, and bit-terwort, belongs to family Gentianaceae. GL belongs to genus Gentiana, which is a rich natural source of iridoids, secoiridoids, xantones, flavonoids, triterpenoids, and carbohydrates. Medicinal plants from Gentiana species have anti-oxidant, anti-inflammatory, anti-mitogenic, anti-proliferative, and lipid-lowering effects, as well as a cardioprotective, hypotensive, vasodilator and anti-platelet activities. Objective: We reviewed the recent literature related to the effects of Gentiana species, and their active components on vascular diseases. Methods: Data used for this review were obtained by searching the electronic database [PUB-MED/MEDLINE 1973-February 2020]. The primary data search terms of interest were: Gentiana lutea, Gentienacea family, phytochemistry, vascular diseases, treatment of vascular diseases, anti-oxidant, anti-inflammatory, anti-atherogenic. Conclusion: Gentiana species and their constituents affect many different factors related to vascular disease development and progression. Therefore, Gentiana-based therapeutics represent potentially use-ful drugs for the management of vascular diseases. © 2021 Bentham Science Publishers.",
journal = "Current Vascular Pharmacology",
title = "Effects of Gentiana lutea Root on Vascular Diseases",
volume = "19",
number = "4",
pages = "359-369",
doi = "10.2174/1570161118666200529111314"
}
Joksić, G., Radak, Đ. J., Sudar-Milovanović, E., Obradović, M. M., Radovanović, J. V.,& Isenović, E. R.. (2021). Effects of Gentiana lutea Root on Vascular Diseases. in Current Vascular Pharmacology, 19(4), 359-369.
https://doi.org/10.2174/1570161118666200529111314
Joksić G, Radak ĐJ, Sudar-Milovanović E, Obradović MM, Radovanović JV, Isenović ER. Effects of Gentiana lutea Root on Vascular Diseases. in Current Vascular Pharmacology. 2021;19(4):359-369.
doi:10.2174/1570161118666200529111314 .
Joksić, Gordana, Radak, Đorđe J., Sudar-Milovanović, Emina, Obradović, Milan M., Radovanović, Jelena V., Isenović, Esma R., "Effects of Gentiana lutea Root on Vascular Diseases" in Current Vascular Pharmacology, 19, no. 4 (2021):359-369,
https://doi.org/10.2174/1570161118666200529111314 . .
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