Sensitivity of Lung Carcinoma Cells to γ-rays and Erlotinib
Authors
Keta, Otilija D.Bulat, Tanja M.
Korićanac, Lela
Todorović, Dragana
Privitera, G.
Petrović, Ivan M.
Ristić-Fira, Aleksandra
Conference object (Published version)
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Society of Physical Chemists of Serbia
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In order to increase radio-sensitivity of human lung adenocarcinoma NCI-H1568
cells, targeted therapy drug, erlotinib was used. The impact of radiation and
erlotinib on cell behaviour was analyzed using three biological endpoints.
Irradiations with γ-rays resulted in reduction of cell survival, viability and
proliferation. Erlotinib significantly inhibited cell growth and proliferation
capacity. Combined treatments with radiation and erlotinib showed high level of
reduction of cell viability and proliferation. Preliminary data encourage further
investigations of mechanisms underlying the radiation responses enhanced by
erlotinib.
Source:
Physical chemistry 2012 : 11th international conference on fundamental and applied aspects of physical chemistry, 2012, 1, 382-384Publisher:
- Society of Physical Chemists of Serbia
Note:
- Physical chemistry 2012 : 11th international conference on fundamental and applied aspects of physical chemistry; Belgrade (Serbia); 24-28 September 2012
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VinčaTY - CONF AU - Keta, Otilija D. AU - Bulat, Tanja M. AU - Korićanac, Lela AU - Todorović, Dragana AU - Privitera, G. AU - Petrović, Ivan M. AU - Ristić-Fira, Aleksandra PY - 2012 UR - https://vinar.vin.bg.ac.rs/handle/123456789/9300 AB - In order to increase radio-sensitivity of human lung adenocarcinoma NCI-H1568 cells, targeted therapy drug, erlotinib was used. The impact of radiation and erlotinib on cell behaviour was analyzed using three biological endpoints. Irradiations with γ-rays resulted in reduction of cell survival, viability and proliferation. Erlotinib significantly inhibited cell growth and proliferation capacity. Combined treatments with radiation and erlotinib showed high level of reduction of cell viability and proliferation. Preliminary data encourage further investigations of mechanisms underlying the radiation responses enhanced by erlotinib. PB - Society of Physical Chemists of Serbia C3 - Physical chemistry 2012 : 11th international conference on fundamental and applied aspects of physical chemistry T1 - Sensitivity of Lung Carcinoma Cells to γ-rays and Erlotinib VL - 1 SP - 382 EP - 384 UR - https://hdl.handle.net/21.15107/rcub_vinar_9300 ER -
@conference{ author = "Keta, Otilija D. and Bulat, Tanja M. and Korićanac, Lela and Todorović, Dragana and Privitera, G. and Petrović, Ivan M. and Ristić-Fira, Aleksandra", year = "2012", abstract = "In order to increase radio-sensitivity of human lung adenocarcinoma NCI-H1568 cells, targeted therapy drug, erlotinib was used. The impact of radiation and erlotinib on cell behaviour was analyzed using three biological endpoints. Irradiations with γ-rays resulted in reduction of cell survival, viability and proliferation. Erlotinib significantly inhibited cell growth and proliferation capacity. Combined treatments with radiation and erlotinib showed high level of reduction of cell viability and proliferation. Preliminary data encourage further investigations of mechanisms underlying the radiation responses enhanced by erlotinib.", publisher = "Society of Physical Chemists of Serbia", journal = "Physical chemistry 2012 : 11th international conference on fundamental and applied aspects of physical chemistry", title = "Sensitivity of Lung Carcinoma Cells to γ-rays and Erlotinib", volume = "1", pages = "382-384", url = "https://hdl.handle.net/21.15107/rcub_vinar_9300" }
Keta, O. D., Bulat, T. M., Korićanac, L., Todorović, D., Privitera, G., Petrović, I. M.,& Ristić-Fira, A.. (2012). Sensitivity of Lung Carcinoma Cells to γ-rays and Erlotinib. in Physical chemistry 2012 : 11th international conference on fundamental and applied aspects of physical chemistry Society of Physical Chemists of Serbia., 1, 382-384. https://hdl.handle.net/21.15107/rcub_vinar_9300
Keta OD, Bulat TM, Korićanac L, Todorović D, Privitera G, Petrović IM, Ristić-Fira A. Sensitivity of Lung Carcinoma Cells to γ-rays and Erlotinib. in Physical chemistry 2012 : 11th international conference on fundamental and applied aspects of physical chemistry. 2012;1:382-384. https://hdl.handle.net/21.15107/rcub_vinar_9300 .
Keta, Otilija D., Bulat, Tanja M., Korićanac, Lela, Todorović, Dragana, Privitera, G., Petrović, Ivan M., Ristić-Fira, Aleksandra, "Sensitivity of Lung Carcinoma Cells to γ-rays and Erlotinib" in Physical chemistry 2012 : 11th international conference on fundamental and applied aspects of physical chemistry, 1 (2012):382-384, https://hdl.handle.net/21.15107/rcub_vinar_9300 .