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dc.creatorRadulovic, Niko S.
dc.creatorRandjelovic, Pavle J.
dc.creatorStojanovic, Nikola M.
dc.creatorCakic, Nevenka D.
dc.creatorBogdanović, Goran A.
dc.creatorZivanovic, Ana V.
dc.date.accessioned2018-03-01T16:36:27Z
dc.date.available2018-03-01T16:36:27Z
dc.date.issued2015
dc.identifier.issn0963-9969 (print)
dc.identifier.issn1873-7145 (electronic)
dc.identifier.urihttp://vinar.vin.bg.ac.rs/handle/123456789/874
dc.description.abstractCallistemon citrinus (Myrtaceae) is a shrub native to Australia. Its flowers have been used as indigenous food among the aboriginal Australians. Numerous diseases, such as bacterial, fungal, viral and parasite infections have traditionally been treated with this plant. Gas chromatography mass spectrometry (GC/MS) analyses of the flower and leaf extracts of C citrinus revealed the presence of a major constituent, a phloroglucinol, dihydroxy-4-methoxyphenyl)-3-methylbutan-1-one (1) (up to 382.2 mg per 1 g of the flower extracts). Compound 1 was for the first time identified in this genus. This phloroglucinol exhibited potent antinociceptive and anti-inflammatory activities in a dose-dependent manner. In addition, this compound displayed strong in vitro antioxidant activity which could be easily connected with both anti-inflammatory and antinociceptive effects. Thus, compound 1, as a plant constituent present in the diet of Aboriginal people, that helps with inflammation and pain, could have given them a better chance of survival in harsh conditions of the environment. (C) 2015 Elsevier Ltd. All rights reserved.en
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172061/RS//
dc.rightsrestrictedAccessen
dc.sourceFood Research Internationalen
dc.subject1-(2,6-Dihydroxy-4-methoxyphenyl)-3-methylbutan-1-oneen
dc.subjectFlowersen
dc.subjectAboriginal bush foodsen
dc.subjectAntioxidant phloroglucinolen
dc.subjectAntinociceptiveen
dc.subjectAnti-inflammatoryen
dc.titleAboriginal bush foods: A major phloroglucinol from Crimson Bottlebrush flowers (Callistemon citrinus, Myrtaceae) displays strong antinociceptive and anti-inflammatory activityen
dc.typearticleen
dcterms.abstractЗивановиц, Aна В.; Радуловиц, Нико С.; Цакиц, Невенка Д.; Рандјеловиц, Павле Ј.; Стојановиц, Никола М.; Богдановић Горан;
dc.citation.volume77
dc.citation.issueSI
dc.citation.spage280
dc.citation.epage289
dc.identifier.wos000367409900025
dc.identifier.doi10.1016/j.foodres.2015.02.023
dc.citation.otherPart number: 2, Special Issue: SI
dc.citation.rankM21
dc.identifier.scopus2-s2.0-84947045789


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