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dc.creatorĐurđić, Slađana
dc.creatorStanković, Vesna
dc.creatorPerić, Marko R.
dc.creatorOgnjanović, Miloš
dc.creatorŠvorc, Lubomir
dc.creatorMutić, Jelena J.
dc.creatorStanković, Dalibor M.
dc.date.accessioned2020-05-13T12:38:47Z
dc.date.available2020-05-13T12:38:47Z
dc.date.issued2019
dc.identifier.issn0013-4651
dc.identifier.urihttp://vinar.vin.bg.ac.rs/handle/123456789/8615
dc.description.abstractIn present work boron doped diamond (BDD) electrode was applied for studying electrochemical behavior, as well as for quantitative determination of natural alkaloid, tubocurarine (arrow poison/ TUB). Electrochemical behavior was investigated using several organic solvents and aqueous buffers, at different pHs, as supporting electrolytes. After selection of the most appropriate supporting electrolyte and investigation of its electrochemical behavior, analytical procedures for quantitative analysis of TUB were developed in an acetonitrile/methanol (80:20) mixture and in 1 mol L−1 nitric acid, which had linear quantification ranges from 4 × 10−6 to 1 × 10−4 mol L−1 (LOD = 3.07 × 10−6 mol L−1) and 4 × 10−6 to 9 × 10−5 mol L−1 (LOD = 2.45 × 10−6 mol L−1 and 5.28 × 10−7 mol L−1, depending on the selected peak), respectively. The oxidation mechanism of TUB was proposed from the theoretical aspect. Remarkable selectivity and good sensitivity were obtained after the TUB quantification method was optimized, allowing application of the developed method for TUB quantification in biological fluids, with excellent reproducibility, accuracy and precision.en
dc.language.isoen
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172030/RS//
dc.relationGrant Agency of the Slovak Republic [1/0489/16]
dc.rightsrestrictedAccess
dc.sourceJournal of The Electrochemical Society
dc.titleElectrochemistry of the Arrow Poison, Tubocurarine, Using Boron Doped Diamond Electrode: Experimental and Theoretical Approachesen
dc.typearticleen
dc.rights.licenseARR
dcterms.abstractОгњановић, М; Шворц, Ľ; Мутић, Ј; Станковић, Далибор М.; Ђурђић, С.; Станковић, В.; Перић, М;
dc.rights.holder© 2019 The Electrochemical Society
dc.citation.volume166
dc.citation.issue14
dc.citation.spageG157
dc.citation.epageG161
dc.identifier.wos000490166300001
dc.identifier.doi10.1149/2.1241914jes
dc.citation.rankM21
dc.type.versionpublishedVersion
dc.identifier.scopus2-s2.0-85074076971


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