Tetravalent Metal Ion Guests in Polyoxopalladate Chemistry: Synthesis and Anticancer Activity of [MO 8 Pd 12 (PO 4 ) 8 ] 12– (M = Sn IV , Pb IV )
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2019
Authors
Yang, PengMa, Tian
Lang, Zhongling
Misirlić-Denčić, Sonja

Isaković, Anđelka

Benyei, Attila
Čolović, Mirjana B.

Marković, Ivanka

Krstić, Danijela Z.

Poblet, Josep M.

Lin, Zhengguo

Kortz, Ulrich
Article (Published version)

© 2019 American Chemical Society
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The first two examples of polyoxopalladates(II) (POPs) containing tetravalent metal ion guests, [MO8Pd12(PO4)8]12- (M = SnIV, PbIV), have been prepared and structurally characterized in the solid state, solution, and gas phase. The interactions of the metal ion guests and the palladium-oxo shell were studied by theoretical calculations. The POPs were shown to possess anticancer activity by causing oxidative stress inducing caspase activation and consecutive apoptosis of leukemic cells.
Source:
Inorganic Chemistry, 2019, 58, 17, 11294-11299Funding / projects:
- German Research Foundation (DFG) [DFG-KO-2288/20-1]
- German Research Foundation (DFG) [DEG-KO-2288/16-1]
- Jacobs University
- China Scholarship Council
- Spanish Ministry of Science [CTQ2017-87269-P]
- Generalitat de Catalunya [2017SGR629]
- ICREA
- CMST COST Action [CM1203]
- Modulation of intracellular energy balance-controlling signalling pathways in therapy of cancer and neuro-immuno-endocrine disorders (RS-41025)
- National Natural Science Foundation of China [21701010]
- Hungarian National Research, Development and Innovation Office - NKFIH [NKFI NN 128368]
DOI: 10.1021/acs.inorgchem.9b01129
ISSN: 0020-1669
PubMed: 31411862
WoS: 000484066500006
Scopus: 2-s2.0-85071784200
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VinčaTY - JOUR AU - Yang, Peng AU - Ma, Tian AU - Lang, Zhongling AU - Misirlić-Denčić, Sonja AU - Isaković, Anđelka AU - Benyei, Attila AU - Čolović, Mirjana B. AU - Marković, Ivanka AU - Krstić, Danijela Z. AU - Poblet, Josep M. AU - Lin, Zhengguo AU - Kortz, Ulrich PY - 2019 UR - https://vinar.vin.bg.ac.rs/handle/123456789/8499 AB - The first two examples of polyoxopalladates(II) (POPs) containing tetravalent metal ion guests, [MO8Pd12(PO4)8]12- (M = SnIV, PbIV), have been prepared and structurally characterized in the solid state, solution, and gas phase. The interactions of the metal ion guests and the palladium-oxo shell were studied by theoretical calculations. The POPs were shown to possess anticancer activity by causing oxidative stress inducing caspase activation and consecutive apoptosis of leukemic cells. T2 - Inorganic Chemistry T1 - Tetravalent Metal Ion Guests in Polyoxopalladate Chemistry: Synthesis and Anticancer Activity of [MO 8 Pd 12 (PO 4 ) 8 ] 12– (M = Sn IV , Pb IV ) VL - 58 IS - 17 SP - 11294 EP - 11299 DO - 10.1021/acs.inorgchem.9b01129 ER -
@article{ author = "Yang, Peng and Ma, Tian and Lang, Zhongling and Misirlić-Denčić, Sonja and Isaković, Anđelka and Benyei, Attila and Čolović, Mirjana B. and Marković, Ivanka and Krstić, Danijela Z. and Poblet, Josep M. and Lin, Zhengguo and Kortz, Ulrich", year = "2019", abstract = "The first two examples of polyoxopalladates(II) (POPs) containing tetravalent metal ion guests, [MO8Pd12(PO4)8]12- (M = SnIV, PbIV), have been prepared and structurally characterized in the solid state, solution, and gas phase. The interactions of the metal ion guests and the palladium-oxo shell were studied by theoretical calculations. The POPs were shown to possess anticancer activity by causing oxidative stress inducing caspase activation and consecutive apoptosis of leukemic cells.", journal = "Inorganic Chemistry", title = "Tetravalent Metal Ion Guests in Polyoxopalladate Chemistry: Synthesis and Anticancer Activity of [MO 8 Pd 12 (PO 4 ) 8 ] 12– (M = Sn IV , Pb IV )", volume = "58", number = "17", pages = "11294-11299", doi = "10.1021/acs.inorgchem.9b01129" }
Yang, P., Ma, T., Lang, Z., Misirlić-Denčić, S., Isaković, A., Benyei, A., Čolović, M. B., Marković, I., Krstić, D. Z., Poblet, J. M., Lin, Z.,& Kortz, U.. (2019). Tetravalent Metal Ion Guests in Polyoxopalladate Chemistry: Synthesis and Anticancer Activity of [MO 8 Pd 12 (PO 4 ) 8 ] 12– (M = Sn IV , Pb IV ). in Inorganic Chemistry, 58(17), 11294-11299. https://doi.org/10.1021/acs.inorgchem.9b01129
Yang P, Ma T, Lang Z, Misirlić-Denčić S, Isaković A, Benyei A, Čolović MB, Marković I, Krstić DZ, Poblet JM, Lin Z, Kortz U. Tetravalent Metal Ion Guests in Polyoxopalladate Chemistry: Synthesis and Anticancer Activity of [MO 8 Pd 12 (PO 4 ) 8 ] 12– (M = Sn IV , Pb IV ). in Inorganic Chemistry. 2019;58(17):11294-11299. doi:10.1021/acs.inorgchem.9b01129 .
Yang, Peng, Ma, Tian, Lang, Zhongling, Misirlić-Denčić, Sonja, Isaković, Anđelka, Benyei, Attila, Čolović, Mirjana B., Marković, Ivanka, Krstić, Danijela Z., Poblet, Josep M., Lin, Zhengguo, Kortz, Ulrich, "Tetravalent Metal Ion Guests in Polyoxopalladate Chemistry: Synthesis and Anticancer Activity of [MO 8 Pd 12 (PO 4 ) 8 ] 12– (M = Sn IV , Pb IV )" in Inorganic Chemistry, 58, no. 17 (2019):11294-11299, https://doi.org/10.1021/acs.inorgchem.9b01129 . .