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Point-of-care amperometric determination of L-dopa using an inkjet-printed carbon nanotube electrode modified with dandelion-like MnO2 microspheres

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Authors
Stanković, Dalibor M.
Jović, Milica
Ognjanović, Miloš
Lesch, Andreas
Fabian, Martin
Girault, Hubert H.
Antić, Bratislav
Article (Published version)
,
© 2019, Springer-Verlag GmbH Austria, part of Springer Nature
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Abstract
An electrochemical sensor is described for the determination of L-dopa (levodopa; 3,4-dihydroxyphenylalanine). An inkjet-printed carbon nanotube (IJPCNT) electrode was modified with manganese dioxide microspheres by drop-casting. They coating was characterized by field emission scanning electron microscopy, Fourier-transform infrared spectroscopy and X-ray powder diffraction. The sensor, best operated at a working voltage of 0.3 V, has a linear response in the 0.1 to 10 μM L-dopa concentration range, a 54 nM detection limit, excellent reproducibility, repeatability and selectivity. The amperometric approach was applied to the determination of L-dopa in spiked biological fluids and displayed satisfactory accuracy and precision. [Figure not available: see fulltext.]. © 2019, Springer-Verlag GmbH Austria, part of Springer Nature.
Keywords:
Levodopa / Electrochemical sensor / Manganese dioxide / Cyclic voltammetry / Amperometry / Point-of-care
Source:
Microchimica Acta, 2019, 186, 8, 532-
Funding / projects:
  • Strengthening of the MagBioVin Research and Innovation Team for Development of Novel Approaches for Tumour Therapy based on Nanostructured Materials (EU-621375)
  • Application of advanced oxidation processes and nanostructured oxide materials for the removal of pollutants from the environment, development and optimisation of instrumental techniques for efficiency monitoring (RS-172030)
  • Allergens, antibodies, enzymes and small physiologically important molecules: design, structure, function and relevance (RS-172049)

DOI: 10.1007/s00604-019-3644-x

ISSN: 0026-3672; 1436-5073

PubMed: 31309336

WoS: 000475700700001

Scopus: 2-s2.0-85069222154
[ Google Scholar ]
17
14
URI
https://vinar.vin.bg.ac.rs/handle/123456789/8394
Collections
  • Radovi istraživača
Institution/Community
Vinča
TY  - JOUR
AU  - Stanković, Dalibor M.
AU  - Jović, Milica
AU  - Ognjanović, Miloš
AU  - Lesch, Andreas
AU  - Fabian, Martin
AU  - Girault, Hubert H.
AU  - Antić, Bratislav
PY  - 2019
UR  - https://vinar.vin.bg.ac.rs/handle/123456789/8394
AB  - An electrochemical sensor is described for the determination of L-dopa (levodopa; 3,4-dihydroxyphenylalanine). An inkjet-printed carbon nanotube (IJPCNT) electrode was modified with manganese dioxide microspheres by drop-casting. They coating was characterized by field emission scanning electron microscopy, Fourier-transform infrared spectroscopy and X-ray powder diffraction. The sensor, best operated at a working voltage of 0.3 V, has a linear response in the 0.1 to 10 μM L-dopa concentration range, a 54 nM detection limit, excellent reproducibility, repeatability and selectivity. The amperometric approach was applied to the determination of L-dopa in spiked biological fluids and displayed satisfactory accuracy and precision. [Figure not available: see fulltext.]. © 2019, Springer-Verlag GmbH Austria, part of Springer Nature.
T2  - Microchimica Acta
T1  - Point-of-care amperometric determination of L-dopa using an inkjet-printed carbon nanotube electrode modified with dandelion-like MnO2 microspheres
VL  - 186
IS  - 8
SP  - 532
DO  - 10.1007/s00604-019-3644-x
ER  - 
@article{
author = "Stanković, Dalibor M. and Jović, Milica and Ognjanović, Miloš and Lesch, Andreas and Fabian, Martin and Girault, Hubert H. and Antić, Bratislav",
year = "2019",
abstract = "An electrochemical sensor is described for the determination of L-dopa (levodopa; 3,4-dihydroxyphenylalanine). An inkjet-printed carbon nanotube (IJPCNT) electrode was modified with manganese dioxide microspheres by drop-casting. They coating was characterized by field emission scanning electron microscopy, Fourier-transform infrared spectroscopy and X-ray powder diffraction. The sensor, best operated at a working voltage of 0.3 V, has a linear response in the 0.1 to 10 μM L-dopa concentration range, a 54 nM detection limit, excellent reproducibility, repeatability and selectivity. The amperometric approach was applied to the determination of L-dopa in spiked biological fluids and displayed satisfactory accuracy and precision. [Figure not available: see fulltext.]. © 2019, Springer-Verlag GmbH Austria, part of Springer Nature.",
journal = "Microchimica Acta",
title = "Point-of-care amperometric determination of L-dopa using an inkjet-printed carbon nanotube electrode modified with dandelion-like MnO2 microspheres",
volume = "186",
number = "8",
pages = "532",
doi = "10.1007/s00604-019-3644-x"
}
Stanković, D. M., Jović, M., Ognjanović, M., Lesch, A., Fabian, M., Girault, H. H.,& Antić, B.. (2019). Point-of-care amperometric determination of L-dopa using an inkjet-printed carbon nanotube electrode modified with dandelion-like MnO2 microspheres. in Microchimica Acta, 186(8), 532.
https://doi.org/10.1007/s00604-019-3644-x
Stanković DM, Jović M, Ognjanović M, Lesch A, Fabian M, Girault HH, Antić B. Point-of-care amperometric determination of L-dopa using an inkjet-printed carbon nanotube electrode modified with dandelion-like MnO2 microspheres. in Microchimica Acta. 2019;186(8):532.
doi:10.1007/s00604-019-3644-x .
Stanković, Dalibor M., Jović, Milica, Ognjanović, Miloš, Lesch, Andreas, Fabian, Martin, Girault, Hubert H., Antić, Bratislav, "Point-of-care amperometric determination of L-dopa using an inkjet-printed carbon nanotube electrode modified with dandelion-like MnO2 microspheres" in Microchimica Acta, 186, no. 8 (2019):532,
https://doi.org/10.1007/s00604-019-3644-x . .

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