Link Between Oxidative Stress and Acute Brain Ischemia
Само за регистроване кориснике
2014
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The pathogenesis of acute brain ischemia (ABI) is highly complex and involves multiple mechanisms including free radical generation. Imbalance between the cellular production of free radicals and the ability of cells to defend against them is referred to as oxidative stress. Oxidative stress is one of the mechanisms contributing to neuronal damage, potentially induced through the ABI. Through interactions with a large number of molecules, reactive oxygen species may irreversibly destroy or alter the function of the cellular lipids, proteins, and nucleic acids and initiate cell signaling pathways after cerebral ischemia. Future investigations should focus on the understanding of oxidative stress mechanisms and neuro-protection in order to discover new treatment targets.
Кључне речи:
oxidative stress / free radicals / acute brain ischemia / strokeИзвор:
Angiology, 2014, 65, 8, 667-676Финансирање / пројекти:
- Каротидна болест у Србији - патолошка динамика, превенција, дијагностика и иновативни терапијски поступци (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-41002)
- Хормонска регулација експресије и активности азот оксид синтазе и натријум-калијумове пумпе у експерименталним моделима инсулинске резистенције, дијабетеса и кардиоваскуларних поремећаја (RS-MESTD-Basic Research (BR or ON)-173033)
DOI: 10.1177/0003319713506516
ISSN: 0003-3197; 1940-1574
PubMed: 24132856
WoS: 000340715700003
Scopus: 2-s2.0-84905923659
Институција/група
VinčaTY - JOUR AU - Radak, Đorđe J. AU - Resanović, Ivana AU - Isenović, Esma R. PY - 2014 UR - https://vinar.vin.bg.ac.rs/handle/123456789/79 AB - The pathogenesis of acute brain ischemia (ABI) is highly complex and involves multiple mechanisms including free radical generation. Imbalance between the cellular production of free radicals and the ability of cells to defend against them is referred to as oxidative stress. Oxidative stress is one of the mechanisms contributing to neuronal damage, potentially induced through the ABI. Through interactions with a large number of molecules, reactive oxygen species may irreversibly destroy or alter the function of the cellular lipids, proteins, and nucleic acids and initiate cell signaling pathways after cerebral ischemia. Future investigations should focus on the understanding of oxidative stress mechanisms and neuro-protection in order to discover new treatment targets. T2 - Angiology T1 - Link Between Oxidative Stress and Acute Brain Ischemia VL - 65 IS - 8 SP - 667 EP - 676 DO - 10.1177/0003319713506516 ER -
@article{ author = "Radak, Đorđe J. and Resanović, Ivana and Isenović, Esma R.", year = "2014", abstract = "The pathogenesis of acute brain ischemia (ABI) is highly complex and involves multiple mechanisms including free radical generation. Imbalance between the cellular production of free radicals and the ability of cells to defend against them is referred to as oxidative stress. Oxidative stress is one of the mechanisms contributing to neuronal damage, potentially induced through the ABI. Through interactions with a large number of molecules, reactive oxygen species may irreversibly destroy or alter the function of the cellular lipids, proteins, and nucleic acids and initiate cell signaling pathways after cerebral ischemia. Future investigations should focus on the understanding of oxidative stress mechanisms and neuro-protection in order to discover new treatment targets.", journal = "Angiology", title = "Link Between Oxidative Stress and Acute Brain Ischemia", volume = "65", number = "8", pages = "667-676", doi = "10.1177/0003319713506516" }
Radak, Đ. J., Resanović, I.,& Isenović, E. R.. (2014). Link Between Oxidative Stress and Acute Brain Ischemia. in Angiology, 65(8), 667-676. https://doi.org/10.1177/0003319713506516
Radak ĐJ, Resanović I, Isenović ER. Link Between Oxidative Stress and Acute Brain Ischemia. in Angiology. 2014;65(8):667-676. doi:10.1177/0003319713506516 .
Radak, Đorđe J., Resanović, Ivana, Isenović, Esma R., "Link Between Oxidative Stress and Acute Brain Ischemia" in Angiology, 65, no. 8 (2014):667-676, https://doi.org/10.1177/0003319713506516 . .