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Spectroscopic characterization of bone tissue of experimental animals after glucocorticoid treatment and recovery period

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Authors
Mitić, Žarko
Najman, Stevo
Cakić, Milorad
Ajduković, Zorica
Ignjatović, Nenad L.
Nikolić, Ružica
Nikolić, Goran
Stojanović, Sanja
Vukelić, Marija
Trajanović, Miroslav
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Abstract
The influence of glucocorticoids on the composition and mineral/organic content of the mandible in tested animals after recovery and healing phase was investigated in this work. The results of FTIR analysis demonstrated that bone tissue composition was changed after glucocorticoid treatment. The increase of calcium, magnesium, phosphorus content and mineral part of bones was statistically significant in recovery phase and in treatment phase that included calcitonin and thymus extract. Some changes also happened in the organic part of the matrix, as indicated by intensity changes for already present IR bands and the appearance of new IR bands in the region 3500–1300 cm−1.
Keywords:
FTIR / glucocorticoids / mandible / AAS / minerals
Source:
Journal of Molecular Structure, 2014, 315-320
Publisher:
  • Elsevier

DOI: 10.1016/j.molstruc.2014.06.006

ISSN: 0022-2860

WoS: 000340315200041

Scopus: 2-s2.0-84903718099
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URI
http://dais.sanu.ac.rs/123456789/554
http://www.itn.sanu.ac.rs/opus4/frontdoor/index/index/docId/822
http://vinar.vin.bg.ac.rs/handle/123456789/7476
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Vinča

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