Production of food-grade multiple emulsions with high encapsulation yield using oscillating membrane emulsification
Апстракт
Food-grade water-in-oil-in-water (W/O/W) multiple emulsions with a volume median diameter of outer droplets of 50-210 mu m were produced by injecting a water-in-oil (W/O) emulsion at the flux of 30 L m(-2) h(-1) through a 10-mu m pore electroplated nickel membrane oscillating at 10-90 Hz frequency and 0.1-5 mm amplitude in 2 wt% aqueous Tween(R) 20 (polyoxyethylene sorbitan monolaurate) solution. The oil phase in the primary W/O emulsion was 5 wt% PGPR (polyglycerol polyricinoleate) dissolved in sunflower oil and the content of water phase in the W/O emulsion was 30 vol%. The size of outer droplets was precisely controlled by the amplitude and frequency of membrane oscillation. Only 3-5% of the inner droplets with a mean diameter of 0.54 mu m were released into the outer aqueous phase during membrane emulsification. A sustained release of 200 ppm copper (II) loaded in the inner aqueous phase was investigated over 7 days. 95% of Cu(II) initially present in the inner water phase was rele...ased in the first 2 days from 56-mu m diameter multiple emulsion droplets and less than 15% of Cu(II) was released over the same interval from 122 mu m droplets. The release rate of Cu(II) decreased with increasing the size of outer droplets and followed non-zero-order kinetics with a release exponent of 0.3-0.5. The prepared multiple emulsions can be used for controlled release of hydrophilic actives in the pharmaceutical, food, and cosmetic industry. (C) 2014 Elsevier B.V. All rights reserved.
Кључне речи:
Multiple emulsion / Oscillating membrane / Sustained release / Membrane emulsification / MicroencapsulationИзвор:
Colloids and Surfaces. A: Physicochemical and Engineering Aspects, 2014, 458, 78-84Напомена:
- 7th Formula Conference, Jul 01-04, 2013, Mulhouse, France
DOI: 10.1016/j.colsurfa.2014.05.011
ISSN: 0927-7757; 1873-4359
WoS: 000341876300011
Scopus: 2-s2.0-84906262194
Колекције
Институција/група
VinčaTY - JOUR AU - Vladisavljević, Goran T. AU - Wang, Bing AU - Dragosavac, Marijana M. AU - Holdich, Richard G. PY - 2014 UR - https://vinar.vin.bg.ac.rs/handle/123456789/7010 AB - Food-grade water-in-oil-in-water (W/O/W) multiple emulsions with a volume median diameter of outer droplets of 50-210 mu m were produced by injecting a water-in-oil (W/O) emulsion at the flux of 30 L m(-2) h(-1) through a 10-mu m pore electroplated nickel membrane oscillating at 10-90 Hz frequency and 0.1-5 mm amplitude in 2 wt% aqueous Tween(R) 20 (polyoxyethylene sorbitan monolaurate) solution. The oil phase in the primary W/O emulsion was 5 wt% PGPR (polyglycerol polyricinoleate) dissolved in sunflower oil and the content of water phase in the W/O emulsion was 30 vol%. The size of outer droplets was precisely controlled by the amplitude and frequency of membrane oscillation. Only 3-5% of the inner droplets with a mean diameter of 0.54 mu m were released into the outer aqueous phase during membrane emulsification. A sustained release of 200 ppm copper (II) loaded in the inner aqueous phase was investigated over 7 days. 95% of Cu(II) initially present in the inner water phase was released in the first 2 days from 56-mu m diameter multiple emulsion droplets and less than 15% of Cu(II) was released over the same interval from 122 mu m droplets. The release rate of Cu(II) decreased with increasing the size of outer droplets and followed non-zero-order kinetics with a release exponent of 0.3-0.5. The prepared multiple emulsions can be used for controlled release of hydrophilic actives in the pharmaceutical, food, and cosmetic industry. (C) 2014 Elsevier B.V. All rights reserved. T2 - Colloids and Surfaces. A: Physicochemical and Engineering Aspects T1 - Production of food-grade multiple emulsions with high encapsulation yield using oscillating membrane emulsification VL - 458 SP - 78 EP - 84 DO - 10.1016/j.colsurfa.2014.05.011 ER -
@article{ author = "Vladisavljević, Goran T. and Wang, Bing and Dragosavac, Marijana M. and Holdich, Richard G.", year = "2014", abstract = "Food-grade water-in-oil-in-water (W/O/W) multiple emulsions with a volume median diameter of outer droplets of 50-210 mu m were produced by injecting a water-in-oil (W/O) emulsion at the flux of 30 L m(-2) h(-1) through a 10-mu m pore electroplated nickel membrane oscillating at 10-90 Hz frequency and 0.1-5 mm amplitude in 2 wt% aqueous Tween(R) 20 (polyoxyethylene sorbitan monolaurate) solution. The oil phase in the primary W/O emulsion was 5 wt% PGPR (polyglycerol polyricinoleate) dissolved in sunflower oil and the content of water phase in the W/O emulsion was 30 vol%. The size of outer droplets was precisely controlled by the amplitude and frequency of membrane oscillation. Only 3-5% of the inner droplets with a mean diameter of 0.54 mu m were released into the outer aqueous phase during membrane emulsification. A sustained release of 200 ppm copper (II) loaded in the inner aqueous phase was investigated over 7 days. 95% of Cu(II) initially present in the inner water phase was released in the first 2 days from 56-mu m diameter multiple emulsion droplets and less than 15% of Cu(II) was released over the same interval from 122 mu m droplets. The release rate of Cu(II) decreased with increasing the size of outer droplets and followed non-zero-order kinetics with a release exponent of 0.3-0.5. The prepared multiple emulsions can be used for controlled release of hydrophilic actives in the pharmaceutical, food, and cosmetic industry. (C) 2014 Elsevier B.V. All rights reserved.", journal = "Colloids and Surfaces. A: Physicochemical and Engineering Aspects", title = "Production of food-grade multiple emulsions with high encapsulation yield using oscillating membrane emulsification", volume = "458", pages = "78-84", doi = "10.1016/j.colsurfa.2014.05.011" }
Vladisavljević, G. T., Wang, B., Dragosavac, M. M.,& Holdich, R. G.. (2014). Production of food-grade multiple emulsions with high encapsulation yield using oscillating membrane emulsification. in Colloids and Surfaces. A: Physicochemical and Engineering Aspects, 458, 78-84. https://doi.org/10.1016/j.colsurfa.2014.05.011
Vladisavljević GT, Wang B, Dragosavac MM, Holdich RG. Production of food-grade multiple emulsions with high encapsulation yield using oscillating membrane emulsification. in Colloids and Surfaces. A: Physicochemical and Engineering Aspects. 2014;458:78-84. doi:10.1016/j.colsurfa.2014.05.011 .
Vladisavljević, Goran T., Wang, Bing, Dragosavac, Marijana M., Holdich, Richard G., "Production of food-grade multiple emulsions with high encapsulation yield using oscillating membrane emulsification" in Colloids and Surfaces. A: Physicochemical and Engineering Aspects, 458 (2014):78-84, https://doi.org/10.1016/j.colsurfa.2014.05.011 . .