Show simple item record

dc.creatorĐorđević, Jelena D.
dc.creatorNiciforovic, A.
dc.creatorRadoičić, Marija B.
dc.date.accessioned2018-03-03T14:36:43Z
dc.date.available2018-03-03T14:36:43Z
dc.date.issued2009
dc.identifier.issn0036-0244
dc.identifier.urihttp://vinar.vin.bg.ac.rs/handle/123456789/6816
dc.description.abstractAltered activities of antioxidant defence system enzymes and the levels of free radicals scavengers have been found to correlate with various physiological or pathological conditions, including stress. The aim of this study was to determine the effects of chronic 21 day isolation stress on antioxidant enzymes (AOEs) expression and activity in Wistar rat liver tissue. The serum corticosterone (CORT) and glucose (GLU) levels were also measured, as one of the most important indicators of stress. Our data revealed that in chronic stress conditions, when both CORT and GLU were low, the AOEs expression was markedly induced. This increase in MnSOD, CuZnSOD, and catalase exhibited similar trend implying efficient detoxification of O(2) radical anion and H(2)O(2). However, this trend was not followed by the respective enzyme activity. While the total SOD activity was induced by the stress, catalase activity remained unaltered. This discrepancy led us to a conclusion that chronic isolation stress may cause oxidant-antioxidant imbalance in rat liver tissue, favoring H(2)O(2) accumulation.en
dc.rightsrestrictedAccessen
dc.sourceRussian Journal of Physical Chemistry Aen
dc.titleAntioxidant Enzymes Expression and Activity in Liver of Stressed Wistar Raten
dc.typearticleen
dcterms.abstractЂорђевић Јелена Д.; Радоичић Марија; Ницифоровиц, A.;
dc.citation.volume83
dc.citation.issue9
dc.citation.spage1617
dc.citation.epage1620
dc.identifier.wos000269314100036
dc.identifier.doi10.1134/S0036024409090362
dc.citation.rankM23
dc.description.other9th International Conference on Fundamental and Applied Aspects of Physical Chemistry, Sep 24-26, 2008, Belgrade, Serbiaen
dc.identifier.scopus2-s2.0-69249213742


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record