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dc.creatorVasić, Vesna M.
dc.creatorKojic, D.
dc.creatorKrinulovic, K.
dc.creatorČolović, Mirjana B.
dc.creatorVujačić, Ana V.
dc.creatorStojić, Dragica Lj.
dc.date.accessioned2018-03-03T14:28:23Z
dc.date.available2018-03-03T14:28:23Z
dc.date.issued2007
dc.identifier.issn0036-0244 (print)
dc.identifier.issn1531-863X (electronic)
dc.identifier.urihttp://vinar.vin.bg.ac.rs/handle/123456789/6719
dc.description.abstractTime-dependent interactions of Na+/K+-ATPase, isolated from rat brain synaptic plasma membranes (SPMs), with Cd2+ and Pb2+ ions in a single exposure and in a mixture were investigated in vitro. The interference of the enzyme with these metal ions was studied as a function of different protein concentrations and exposure time. The aim of the work was to investigate the possibility of selective recognition of Cd2+ and Pb2+ ions in a mixture, on the basis of the different rates of their protein-ligand interactions. Decreasing protein concentration increased the sensitivity of Na+/K+-ATPase toward both metals. The selectivity in protein-ligand interactions was obtained by variation of preincubation time (incubation before starting the enzymatic reaction).en
dc.rightsrestrictedAccessen
dc.sourceRussian Journal of Physical Chemistry Aen
dc.titleTime-dependent inhibition of Na+/K+-ATPase induced by single and simultaneous exposure to lead and cadmiumen
dc.typearticleen
dcterms.abstractВасић Весна М; Стојиц, Д.; Кринуловиц, К.; Којиц, Д.; Вујачић-Никезић Aна; Чоловић Мирјана;
dc.citation.volume81
dc.citation.issue9
dc.citation.spage1402
dc.citation.epage1406
dc.identifier.wos000253706400010
dc.identifier.doi10.1134/S0036024407090105
dc.citation.rankM23
dc.description.other8th International Conference on Fundamental and Applied Aspects of Physical Chemistry, Sep 26-29, 2006, Belgrade, Serbiaen
dc.identifier.scopus2-s2.0-34548497579


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