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dc.creatorMićić, Maja M.
dc.creatorMilić-Vukašinović, Tanja
dc.creatorMitrić, Miodrag
dc.creatorJokić, Bojan M.
dc.creatorSuljovrujić, Edin H.
dc.identifier.issn0170-0839 (print)
dc.identifier.issn1436-2449 (electronic)
dc.description.abstractSilver nanoparticles were fabricated via in situ reduction of silver nitrate embedded in swollen P(HEMA/IA) hydrogel, using gamma radiolysis method. Copolymeric hydrogels based on 2-hydroxyethyl methacrylate (HEMA) and itaconic acid (IA), previously synthesised by gamma radiation for wound dressing application, were used as a carrier and a stabilising agent, while ethyl alcohol was used as a free radical scavenger. The influence of different P(HEMA/IA) hydrogels and silver salt concentrations on the size and distribution of nanoparticles was investigated. The Ag/P(HEMA/IA) nanocomposites were characterised by high resolution scanning electron microscopy, energy dispersive spectroscopy, wide-angle X-ray diffraction, UV-Vis spectroscopy and swelling measurements. Escherichia coli (Gram-negative bacterium), Staphylococcus aureus (Gram-positive bacterium) and Candida albicans (fungus) were used to prove the antimicrobial properties of Ag/P(HEMA/IA) nanocomposites. The inhibition kinetics of bacteria growth was investigated by measuring the colony-forming unit. The antimicrobial effectiveness of the Ag/P(HEMA/IA) hydrogel nanocomposite was demonstrated even at small silver concentrations. P(HEMA/IA) hydrogels containing nanosilver particles was found suitable to be used as wound dressing.en
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172026/RS//
dc.sourcePolymer Bulletinen
dc.subjectAg nanoparticles (AgNPs)en
dc.subjectGamma radiationen
dc.subjectP(HEMA/IA) hydrogelen
dc.subjectAntimicrobial activityen
dc.titleRadiation synthesis, characterisation and antimicrobial application of novel copolymeric silver/poly(2-hydroxyethyl methacrylate/itaconic acid) nanocomposite hydrogelsen
dcterms.abstractЈокиц, Б.; Шуљоврујић Един Х.; Митрић Миодраг; Мициц, М.; Милиц, Т. Вукасиновиц;

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