Exposure to polycyclic aromatic hydrocarbons in women from Poland, Serbia and Italy - relation between PAH metabolite excretion, DNA damage, diet and genotype (the EU DIEPHY project)
Nema prikaza
Autori
Nilsson, RobertAntic, Ruza
Berni, Andrea
Dallner, Gustav
Dettbarn, Gerhard
Gromadzinska, Jolanta
Joksić, Gordana
Lundin, Cecilia
Palitti, Fabrizio
Prochazka, Gabriela
Rydzynski, Konrad
Segerback, Dan
Soucek, Pavel
Tekle, Michael
Seidel, Albrecht
Članak u časopisu
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Exposure of the general population to polycyclic aromatic hydrocarbons (PAH) is ubiquitous. The aim of this study was to analyze biomarkers associated with the uptake of PAH in 428 non-smoking women from Lodz (Poland), Viterbo (Italy), Belgrade (Serbia) and from the Pancevo area, where the petrochemical complex was destroyed by the air raids in 1999. Urinary excretion of PAH metabolites was lowest in Italian women, intermediary for Serbian and highest in Polish women, who predominantly excreted hydroxy phenanthrenes as metabolites of phenanthrene. Bulky DNA adduct levels were highest in Italian and Polish women. Genotype or PAH ambient air levels could not explain the dissimilarities between the study groups with respect to biomarker patterns, which probably reflected differences in life style-associated factors.
Ključne reči:
Biomarkers / diet / DNA adducts / genotyping / metabolism / polycyclic aromatic hydrocarbons / polymorphismIzvor:
Biomarkers, 2013, 18, 2, 165-173Finansiranje / projekti:
- EU DG Research [FOOD-CT-2003-505609]
DOI: 10.3109/1354750X.2012.762807
ISSN: 1354-750X
PubMed: 23384313
WoS: 000314976000010
Scopus: 2-s2.0-84873924267
Kolekcije
Institucija/grupa
VinčaTY - JOUR AU - Nilsson, Robert AU - Antic, Ruza AU - Berni, Andrea AU - Dallner, Gustav AU - Dettbarn, Gerhard AU - Gromadzinska, Jolanta AU - Joksić, Gordana AU - Lundin, Cecilia AU - Palitti, Fabrizio AU - Prochazka, Gabriela AU - Rydzynski, Konrad AU - Segerback, Dan AU - Soucek, Pavel AU - Tekle, Michael AU - Seidel, Albrecht PY - 2013 UR - https://vinar.vin.bg.ac.rs/handle/123456789/5310 AB - Exposure of the general population to polycyclic aromatic hydrocarbons (PAH) is ubiquitous. The aim of this study was to analyze biomarkers associated with the uptake of PAH in 428 non-smoking women from Lodz (Poland), Viterbo (Italy), Belgrade (Serbia) and from the Pancevo area, where the petrochemical complex was destroyed by the air raids in 1999. Urinary excretion of PAH metabolites was lowest in Italian women, intermediary for Serbian and highest in Polish women, who predominantly excreted hydroxy phenanthrenes as metabolites of phenanthrene. Bulky DNA adduct levels were highest in Italian and Polish women. Genotype or PAH ambient air levels could not explain the dissimilarities between the study groups with respect to biomarker patterns, which probably reflected differences in life style-associated factors. T2 - Biomarkers T1 - Exposure to polycyclic aromatic hydrocarbons in women from Poland, Serbia and Italy - relation between PAH metabolite excretion, DNA damage, diet and genotype (the EU DIEPHY project) VL - 18 IS - 2 SP - 165 EP - 173 DO - 10.3109/1354750X.2012.762807 ER -
@article{ author = "Nilsson, Robert and Antic, Ruza and Berni, Andrea and Dallner, Gustav and Dettbarn, Gerhard and Gromadzinska, Jolanta and Joksić, Gordana and Lundin, Cecilia and Palitti, Fabrizio and Prochazka, Gabriela and Rydzynski, Konrad and Segerback, Dan and Soucek, Pavel and Tekle, Michael and Seidel, Albrecht", year = "2013", abstract = "Exposure of the general population to polycyclic aromatic hydrocarbons (PAH) is ubiquitous. The aim of this study was to analyze biomarkers associated with the uptake of PAH in 428 non-smoking women from Lodz (Poland), Viterbo (Italy), Belgrade (Serbia) and from the Pancevo area, where the petrochemical complex was destroyed by the air raids in 1999. Urinary excretion of PAH metabolites was lowest in Italian women, intermediary for Serbian and highest in Polish women, who predominantly excreted hydroxy phenanthrenes as metabolites of phenanthrene. Bulky DNA adduct levels were highest in Italian and Polish women. Genotype or PAH ambient air levels could not explain the dissimilarities between the study groups with respect to biomarker patterns, which probably reflected differences in life style-associated factors.", journal = "Biomarkers", title = "Exposure to polycyclic aromatic hydrocarbons in women from Poland, Serbia and Italy - relation between PAH metabolite excretion, DNA damage, diet and genotype (the EU DIEPHY project)", volume = "18", number = "2", pages = "165-173", doi = "10.3109/1354750X.2012.762807" }
Nilsson, R., Antic, R., Berni, A., Dallner, G., Dettbarn, G., Gromadzinska, J., Joksić, G., Lundin, C., Palitti, F., Prochazka, G., Rydzynski, K., Segerback, D., Soucek, P., Tekle, M.,& Seidel, A.. (2013). Exposure to polycyclic aromatic hydrocarbons in women from Poland, Serbia and Italy - relation between PAH metabolite excretion, DNA damage, diet and genotype (the EU DIEPHY project). in Biomarkers, 18(2), 165-173. https://doi.org/10.3109/1354750X.2012.762807
Nilsson R, Antic R, Berni A, Dallner G, Dettbarn G, Gromadzinska J, Joksić G, Lundin C, Palitti F, Prochazka G, Rydzynski K, Segerback D, Soucek P, Tekle M, Seidel A. Exposure to polycyclic aromatic hydrocarbons in women from Poland, Serbia and Italy - relation between PAH metabolite excretion, DNA damage, diet and genotype (the EU DIEPHY project). in Biomarkers. 2013;18(2):165-173. doi:10.3109/1354750X.2012.762807 .
Nilsson, Robert, Antic, Ruza, Berni, Andrea, Dallner, Gustav, Dettbarn, Gerhard, Gromadzinska, Jolanta, Joksić, Gordana, Lundin, Cecilia, Palitti, Fabrizio, Prochazka, Gabriela, Rydzynski, Konrad, Segerback, Dan, Soucek, Pavel, Tekle, Michael, Seidel, Albrecht, "Exposure to polycyclic aromatic hydrocarbons in women from Poland, Serbia and Italy - relation between PAH metabolite excretion, DNA damage, diet and genotype (the EU DIEPHY project)" in Biomarkers, 18, no. 2 (2013):165-173, https://doi.org/10.3109/1354750X.2012.762807 . .