Mass transfer resistance in a liquid-phase microextraction employing a single hollow fiber under unsteady-state conditions
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2012
Authors
Kumrić, KsenijaVladisavljević, Goran T.
Đorđević, Jelena S.
Jonsson, Jan Ake
Trtić-Petrović, Tatjana M.
Article (Published version)
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In this study, the mass transport resistance in liquid-phase microextraction (LPME) in a single hollow fiber was investigated. A mathematical model has been developed for the determination of the overall mass transfer coefficient based on the acceptor phase in an unsteady state. The overall mass transfer coefficient in LPME in a single hollow fiber has been estimated from time-dependent concentration of extracted analyte in the acceptor phase while maintaining a constant analyte concentration in the donor phase. It can be achieved either using a high volume of donor to acceptor phase ratio or tuning the extraction conditions to obtain a low-enrichment factor, so that the analyte concentration in the sample is not significantly influenced by the mass transfer. Two extraction systems have been used to test experimentally the developed model: the extraction of Lu(III) from a buffer solution and the extraction of three local anesthetics from a buffer or plasma solution. The mass transfer r...esistance, defined as a reciprocal values of the mass transfer coefficient, was found to be 1.2 x 103 cm-1 min for Lu(III) under optimal conditions and from 1.96 to 3.3 x 103 cm-1 min for the local anesthetics depending on the acceptor pH and the hydrophobicity of the drug.
Keywords:
Hollow fiber liquid-phase microextraction / Mass transfer coefficient / Mass transfer resistanceSource:
Journal of Separation Science, 2012, 35, 18, 2390-2398Funding / projects:
- Physics and Chemistry with Ion Beams (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-45006)
DOI: 10.1002/jssc.201200497
ISSN: 1615-9306
PubMed: 22997029
WoS: 000309059700005
Scopus: 2-s2.0-84866504965
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VinčaTY - JOUR AU - Kumrić, Ksenija AU - Vladisavljević, Goran T. AU - Đorđević, Jelena S. AU - Jonsson, Jan Ake AU - Trtić-Petrović, Tatjana M. PY - 2012 UR - https://vinar.vin.bg.ac.rs/handle/123456789/5044 AB - In this study, the mass transport resistance in liquid-phase microextraction (LPME) in a single hollow fiber was investigated. A mathematical model has been developed for the determination of the overall mass transfer coefficient based on the acceptor phase in an unsteady state. The overall mass transfer coefficient in LPME in a single hollow fiber has been estimated from time-dependent concentration of extracted analyte in the acceptor phase while maintaining a constant analyte concentration in the donor phase. It can be achieved either using a high volume of donor to acceptor phase ratio or tuning the extraction conditions to obtain a low-enrichment factor, so that the analyte concentration in the sample is not significantly influenced by the mass transfer. Two extraction systems have been used to test experimentally the developed model: the extraction of Lu(III) from a buffer solution and the extraction of three local anesthetics from a buffer or plasma solution. The mass transfer resistance, defined as a reciprocal values of the mass transfer coefficient, was found to be 1.2 x 103 cm-1 min for Lu(III) under optimal conditions and from 1.96 to 3.3 x 103 cm-1 min for the local anesthetics depending on the acceptor pH and the hydrophobicity of the drug. T2 - Journal of Separation Science T1 - Mass transfer resistance in a liquid-phase microextraction employing a single hollow fiber under unsteady-state conditions VL - 35 IS - 18 SP - 2390 EP - 2398 DO - 10.1002/jssc.201200497 ER -
@article{ author = "Kumrić, Ksenija and Vladisavljević, Goran T. and Đorđević, Jelena S. and Jonsson, Jan Ake and Trtić-Petrović, Tatjana M.", year = "2012", abstract = "In this study, the mass transport resistance in liquid-phase microextraction (LPME) in a single hollow fiber was investigated. A mathematical model has been developed for the determination of the overall mass transfer coefficient based on the acceptor phase in an unsteady state. The overall mass transfer coefficient in LPME in a single hollow fiber has been estimated from time-dependent concentration of extracted analyte in the acceptor phase while maintaining a constant analyte concentration in the donor phase. It can be achieved either using a high volume of donor to acceptor phase ratio or tuning the extraction conditions to obtain a low-enrichment factor, so that the analyte concentration in the sample is not significantly influenced by the mass transfer. Two extraction systems have been used to test experimentally the developed model: the extraction of Lu(III) from a buffer solution and the extraction of three local anesthetics from a buffer or plasma solution. The mass transfer resistance, defined as a reciprocal values of the mass transfer coefficient, was found to be 1.2 x 103 cm-1 min for Lu(III) under optimal conditions and from 1.96 to 3.3 x 103 cm-1 min for the local anesthetics depending on the acceptor pH and the hydrophobicity of the drug.", journal = "Journal of Separation Science", title = "Mass transfer resistance in a liquid-phase microextraction employing a single hollow fiber under unsteady-state conditions", volume = "35", number = "18", pages = "2390-2398", doi = "10.1002/jssc.201200497" }
Kumrić, K., Vladisavljević, G. T., Đorđević, J. S., Jonsson, J. A.,& Trtić-Petrović, T. M.. (2012). Mass transfer resistance in a liquid-phase microextraction employing a single hollow fiber under unsteady-state conditions. in Journal of Separation Science, 35(18), 2390-2398. https://doi.org/10.1002/jssc.201200497
Kumrić K, Vladisavljević GT, Đorđević JS, Jonsson JA, Trtić-Petrović TM. Mass transfer resistance in a liquid-phase microextraction employing a single hollow fiber under unsteady-state conditions. in Journal of Separation Science. 2012;35(18):2390-2398. doi:10.1002/jssc.201200497 .
Kumrić, Ksenija, Vladisavljević, Goran T., Đorđević, Jelena S., Jonsson, Jan Ake, Trtić-Petrović, Tatjana M., "Mass transfer resistance in a liquid-phase microextraction employing a single hollow fiber under unsteady-state conditions" in Journal of Separation Science, 35, no. 18 (2012):2390-2398, https://doi.org/10.1002/jssc.201200497 . .