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Chronic Isolation Stress Predisposes the Frontal Cortex but Not the Hippocampus to the Potentially Detrimental Release of Cytochrome c From Mitochondria and the Activation of Caspase-3
(Journal of Neuroscience Research, 2011)
Mitochondria are central integrators and transducers of proapoptotic signals for neuronal apoptosis. The tumor suppressor protein p53 can trigger apoptosis independently of its transcriptional activity, through subcellular ...
Regulation of atrial catecholamine enzymes and adrenoceptor gene expression after chronic stress
(Acta Physiologica Hungarica, 2011)
Chronic stress is a risk factor for the development of numerous psychopathological conditions in humans including depression. Changes in gene expression of tyrosine-hydroxylase (TH), dopamine-beta-hydroxylase (DBH) ...