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The role of G protein coupled receptor kinases in neurocardiovascular pathophysiology

Bojić, Tijana; Sudar, Emina; Mikhailidis, Dimitri P.; Alavantić, Dragan; Isenović, Esma R. (Archives of Medical Science, 2012)

In coronary artery disease the G protein related kinases (GRKs) play a role in desensitization of beta-adrenoreceptors (AR) after coronary occlusion. Targeted deletion and lowering of cardiac myocyte GRK-2 decreases the ...