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The role of long-range intermolecular interactions in discovery of new drugs
(Expert Opinion on Drug Discovery, 2011)
Introduction: Long-range intermolecular interactions (interactions at distances between 100 and 1000 A) play an important role in the interaction between drugs and therapeutic targets, and design techniques based on this ...
Evaluation of the Possible Contribution of Antioxidants Administration in Metabolic Syndrome
(Current Pharmaceutical Design, 2011)
The metabolic syndrome (MetS) is common, and its associated risk burdens of diabetes and cardiovascular disease (CVD) are a major public health problem. The hypothesis that main constituent parameters of the MetS share ...
FAB, ESI and MALDI Mass Spectrometric methods in the study of metallo-drugs and their biomolecular interactions
(Metallomics, 2011)
This review surveys the soft ionisation mass spectrometric methods that are most commonly used for the investigation of the mechanism of interaction between metallo-drugs and biomolecules. In the first part of the review, ...
The Possibilities for Measurement and Characterization of Diesel Engine Fine Particles - a Review
(Thermal Science, 2011)
This review paper considers possible instrumentation for diesel engine fine particles exhaust emission evaluation. The modern diesel engines have extremely low particles emission almost at the level of measurement error ...
The challenge of merging food safety diagnostic needs with quantitative PCR platforms
(Trends in Food Science and Technology, 2011)
The field of food microbiology and safety has experienced an exciting time in the last 10 years. New methods have been introduced to assess safety of foods by targeting pathogenic microorganisms without the need for ...
Involvement of the ADAM 12 in Thrombin-Induced Rats VSMCs Proliferation
(Current Medicinal Chemistry, 2011)
Cardiovascular disease is the largest single cause of mortality and its major underlying pathology is atherosclerosis. The proliferation of vascular smooth muscle cells (VSMCs) is a key event in the pathogenesis of the ...