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Molecular makeup of HIV-1 envelope protein
(International Reviews of Immunology, 2004)
A broad range of structural, functional, and immunological similarities between HIV-1 gp120 and human proteins, especially those participating in immune responses, highlight gp120 as a pleiotropic protein that can in ...
HIV-1 gp120 and immune network
(International Reviews of Immunology, 2004)
It has been demonstrated that the immunodominant V3 loop of HIV-1 gp120 and its flanking regions bear sequence and structural homology to the framework and complementarity-determining regions of human immunoglobulins. It ...
Discovery of New Therapeutic Targets by the Informational Spectrum Method
(Current Protein and Peptide Science, 2008)
The field of bioinformatics has become a major part of the drug discovery pipeline playing a key role in improvement and acceleration of this time and money consuming process. Here we review the application of the informational ...