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Differential Regulation of CuZnSOD Expression in Rat Brain by Acute and/or Chronic Stress
(Cellular and Molecular Neurobiology, 2009)
Neuroendocrine stress (NES) causes increase of glucocorticoids and alters physiological levels of reactive oxygen species production in cells, which might involve modifications in the antioxidant defense system. We ...
The effect of acute or/and chronic stress on the MnSOD protein expression in rat prefrontal cortex and hippocampus
(General Physiology and Biophysics, 2009)
Manganese superoxide dismutase (MnSOD) is the major antioxidant in mitochondria that protect brain from neuroendocrine stress. Although MnSOD is localized in the mitochondria, the immediate subcellular distribution of MnSOD ...
Cranial irradiation modulates hypothalamic-pituitary-adrenal axis activity and corticosteroid receptor expression in the hippocampus of juvenile rat
(General Physiology and Biophysics, 2009)
Glucocorticoids, essential for normal,hypothalamic-pituitary-adrenal (HPA) axis activity, exert their action on the hippocampus through two types of corticosteroid receptors: the glucocorticoid receptor (GR) and the ...