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Identification of Candidate Allosteric Modulators of the M1 Muscarinic Acetylcholine Receptor Which May Improve Vagus Nerve Stimulation in ChronicTinnitus
(Frontiers in Neuroscience, 2017)
Chronic tinnitus is characterized by neuroplastic changes of the auditory cortex. A promising method for therapy of chronic tinnitus is vagus nerve stimulation (VNS) combined with auditory stimulation. The principle of VNS ...
Generalized Poincare Plots-A New Method for Evaluation of Regimes in Cardiac Neural Control in Atrial Fibrillation and Healthy Subjects
(Frontiers in Neuroscience, 2016)
Classical Poincare plot is a standard way to measure nonlinear regulation of cardiovascular control. In our work we propose a generalized form of Poincare plot where we track correlation between the duration of j preceding ...
In silico Therapeutics for Neurogenic Hypertension and Vasovagal Syncope
(Frontiers in Neuroscience, 2016)
Neurocardiovascular diseases (NCVD) are the leading cause of death in the developed world and will remain so till 2020. In these diseases the pathologically changed nervous control of cardiovascular system has the central ...