Search
Now showing items 1-10 of 24
Biochemical Markers of Renal Function
(Current Medicinal Chemistry, 2016)
Kidney damage can be induced by ischemia, autoimmune diseases, hypertension, allograft rejection, metabolic or genetic disorders, infections or toxins. The influence of these factors could result in acute kidney injury ...
Preclinical discovery and development of maraviroc for the treatment of HIV
(Expert Opinion on Drug Discovery, 2015)
Introduction: Maraviroc is a first-in-class antiretroviral (ARV) drug acting on a host cell target (CCR5), which blocks the entry of the HIV virus into the cell. Maraviroc is currently indicated for combination ARV treatment ...
Radiopharmaceutical complexes of technetium and tin: Physicochemical and biochemical research
(Journal of Radioanalytical and Nuclear Chemistry, 1999)
The list of the developed Tc-99m-kits in our research center is given, while the whole research work as a basis of Tc-99m scanning agents production is described. Research involved physico-chemical studies of both types ...
Dense and near-net-shape fabrication of Si3N4 ceramics
(Materials Science and Engineering A: Structural Materials Properties Microstructure and Processing, 2009)
With silicon nitride significant progress has been made in order to search for fully dense, strong, reliable structural ceramics to find wide use in applications at high temperatures which are allowing new and innovative ...
EACVI/EHRA Expert Consensus Document on the role of multi-modality imaging for the evaluation of patients with atrial fibrillation
(European Heart Journal - Cardiovascular Imaging, 2016)
Atrial fibrillation (AF) is the commonest cardiac rhythm disorder. Evaluation of patients with AF requires an electrocardiogram, but imaging techniques should be considered for defining management and driving treatment. ...
Low temperature Ce2Si2O7 polymorph formed by mechanical activation
(Materials Chemistry and Physics, 2006)
Studying solid state reaction between mechanically activated oxide powders of CeO2 and quartz-SiO2, we obtained directly during heat treatment, the low temperature polymorph of Ce2Si2O7 instead of the high temperature ...
Improving attrition rates in Ebola virus drug discovery
(Expert Opinion on Drug Discovery, 2015)
Introduction: The Ebola 2014/2015 outbreak has had devastating effects on the people living in West Africa. The spread of the disease in endemic countries and the potential introduction of sporadic cases in other continents ...
Na+,K+-ATPase as the Target Enzyme for Organic and Inorganic Compounds
(Sensors, 2008)
This paper gives an overview of the literature data concerning specific and non specific inhibitors of Na+,K+-ATPase receptor. The immobilization approaches developed to improve the rather low time and temperature stability ...
CMS physics technical design report, volume II: Physics performance
(Journal of Physics. G: Nuclear and Particle Physics, 2007)
CMS is a general purpose experiment, designed to study the physics of pp collisions at 14 TeV at the Large Hadron Collider ( LHC). It currently involves more than 2000 physicists from more than 150 institutes and 37 ...
FAB, ESI and MALDI Mass Spectrometric methods in the study of metallo-drugs and their biomolecular interactions
(Metallomics, 2011)
This review surveys the soft ionisation mass spectrometric methods that are most commonly used for the investigation of the mechanism of interaction between metallo-drugs and biomolecules. In the first part of the review, ...