Search
Now showing items 1-10 of 40
The role of long-range intermolecular interactions in discovery of new drugs
(Expert Opinion on Drug Discovery, 2011)
Introduction: Long-range intermolecular interactions (interactions at distances between 100 and 1000 A) play an important role in the interaction between drugs and therapeutic targets, and design techniques based on this ...
Interrelatedness between C-reactive protein and oxidized low-density lipoprotein
(Clinical Chemistry and Laboratory Medicine, 2015)
C-reactive protein (CRP) is a marker of inflammation. Atherosclerosis is now recognized as inflammatory disease, and it seems that CRP directly contributes to atherogenesis. Oxidation of low-density lipoprotein (LDL) ...
Evaluation of the Possible Contribution of Antioxidants Administration in Metabolic Syndrome
(Current Pharmaceutical Design, 2011)
The metabolic syndrome (MetS) is common, and its associated risk burdens of diabetes and cardiovascular disease (CVD) are a major public health problem. The hypothesis that main constituent parameters of the MetS share ...
FAB, ESI and MALDI Mass Spectrometric methods in the study of metallo-drugs and their biomolecular interactions
(Metallomics, 2011)
This review surveys the soft ionisation mass spectrometric methods that are most commonly used for the investigation of the mechanism of interaction between metallo-drugs and biomolecules. In the first part of the review, ...
The Possibilities for Measurement and Characterization of Diesel Engine Fine Particles - a Review
(Thermal Science, 2011)
This review paper considers possible instrumentation for diesel engine fine particles exhaust emission evaluation. The modern diesel engines have extremely low particles emission almost at the level of measurement error ...
Toxicity of pristine versus functionalized fullerenes: mechanisms of cell damage and the role of oxidative stress
(Archives of Toxicology, 2012)
The fullerene C-60, due to the physicochemical properties of its spherical cage-like molecule build exclusively from carbon atoms, is able to both scavenge and generate reactive oxygen species. While this unique dual ...
Insulin, Thrombin, ERK1/2 Kinase and Vascular Smooth Muscle Cells Proliferation
(Current Pharmaceutical Design, 2010)
Vascular smooth muscle cells (VSMC) respond to arterial wall injury by intimal proliferation and play a key role in atherogenesis by proliferating and migrating excessively in response to repeated injury, such as hypertension ...
Changes of properties of cured and uncured disiloxane bisbenzocyclobutene thin films under irradiation
(Progress in Organic Coatings, 2013)
The effects induced by alpha-particles and laser beam irradiation in air atmosphere in uncured and cured bisbenzocyclobutene (BCB) 2 mu m thick films, spin-coated on glass/ITO surface have been investigated. alpha-Particle ...
Analytical methods for arsenic speciation analysis
(Journal of the Serbian Chemical Society, 2013)
Arsenic exists in the form of various chemical species differing in their physicochemical behaviour, toxicity, bioavailability and biotransformation. The determination of arsenic species is an important issue for environmental, ...
Regulation of Na+/K+-ATPase by Estradiol and IGF-1 in Cardio-Metabolic Diseases
(Current Pharmaceutical Design, 2017)
Background: The sodium/potassium- adenosine- triphosphatase (Na+/K+-ATPase) is an important mediator in vasculature tone and contractility, and its abnormal regulation has been implicated in many diseases such as obesity, ...