Search
Now showing items 1-10 of 79
miR-21 Might be Involved in Breast Cancer Promotion and Invasion Rather than in Initial Events of Breast Cancer Development
(Molecular Diagnosis and Therapy, 2016)
Breast cancer (BC) is a heterogeneous disease that develops into a large number of varied phenotypes. One of the features used in its classification and therapy selection is invasiveness. MicroRNA-21 (miR-21) is considered ...
Integrated Assessment and Management of Ambient Particulate Matter - International Perspective and Current Research in Serbia
(Chemical Industry and Chemical Engineering Quarterly / CICEQ, 2012)
Air pollution mitigation is a necessity in Serbia, due to its high levels of criteria pollutants in ambient environment. Successful implementation of mitigation measures requires access to sufficient information from ...
Effects of altered hepatic lipid metabolism on regulation of hepatic iNOS
(Clinical Lipidology, 2015)
An altered hepatic lipid metabolism involves multifactorial pathologies such as hepatic inflammation, insulin resistance and oxidative stress. Immunity has an essential role in the regulation of glucose and lipid metabolism ...
Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA)
(World Journal of Emergency Surgery, 2016)
Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients. The cornerstones in the management of complicated IAIs are timely ...
Biochemical Markers of Renal Function
(Current Medicinal Chemistry, 2016)
Kidney damage can be induced by ischemia, autoimmune diseases, hypertension, allograft rejection, metabolic or genetic disorders, infections or toxins. The influence of these factors could result in acute kidney injury ...
Levels of MicroRNA Heterogeneity in Cancer Biology
(Molecular Diagnosis and Therapy, 2017)
MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression, involved in the silencing of messenger RNA (mRNA) translation. The importance of miRNA signatures in disease screening, prognosis, and progression ...
Determination of thermal conductivity of baled agricultural biomass
(Renewable and Sustainable Energy Reviews, 2016)
Modeling of transport phenomena in materials with porous bed features requires thermophysical properties, such as porosity, permeability and thermal conductivity be known. The paper presents experimental data obtained in ...
Track structure modeling in liquid water: A review of the Geant4-DNA very low energy extension of the Geant4 Monte Carlo simulation toolkit
(Physica Medica -European Journal of Medical Physics, 2015)
Understanding the fundamental mechanisms involved in the induction of biological damage by ionizing radiation remains a major challenge of todays radiobiology research. The Monte Carlo simulation of physical, physicochemical ...
Preclinical discovery and development of maraviroc for the treatment of HIV
(Expert Opinion on Drug Discovery, 2015)
Introduction: Maraviroc is a first-in-class antiretroviral (ARV) drug acting on a host cell target (CCR5), which blocks the entry of the HIV virus into the cell. Maraviroc is currently indicated for combination ARV treatment ...
Antidepressant Action on Mitochondrial Dysfunction in Psychiatric Disorders
(Drug Development Research, 2016)
Mitochondria are cell organelles crucial to the production of cellular energy. Several lines of evidence have indicated that mitochondrial dysfunction could be related to the pathophysiology of CNS diseases including bipolar ...