In this study hematological toxicity was analyzed after the single and repeated applications of tiazofurin (TZF). Cellularity of bone marrow, spleen and peripheral blood was examined, spanning the period of fifty days after ...

Tiazofurin (TZF) is a cytostatic drug that leads to depletion of the GTP pool in tumor and normal cells via its active metabolite tiazofurin-adenine dinucleotide (TAD). TAD was detected in different cell lines, but not in ...

A new diatomic molecule-containing endohedral fullerenes were prepared by ion implantation technique (introducing negatively charged C-70 into a low temperature lithium plasma column by a strong exial magnetic field). The ...

Composite biomaterials based on calcium phosphate ceramic due to their high bioactivity are of interest for biological application and bone tissue repair. Structural and microstructural parameters of inorganic constituent ...

The role of heat shock protein 70 (HSP70) expression has been investigated in various types of tumors. There are only little and controversial data about its clinical relevance in colorectal carcinoma, one of the most ...

Purpose: To assess the cytogenetic effects in vitro and in vivo of a non-cytotoxic antitumor agent with biomodulator activity, 8-chloro-3, 5 cyclic adenosine monophosphate (8-Cl-cAMP). Materials and methods: Cytogenetic ...

Phonon spectra of Cd1-xMnxS (x = 0; 0.01; 0.05; 0.1; 0.15; 0.3) nanoparticles (d similar to 4.5 rim) have been investigated by far-infrared reflection (FIR) (spectral range 40 - 600 cm(-1), temperature range 80-300 K) and ...

The mechanism of the synthesis of silicon dioxide thin films on the surface of a stainless steel band substrate, by thermal spraying of a silica sol as a precursor was the subject of this work. The structural design of the ...