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Interrelatedness between C-reactive protein and oxidized low-density lipoprotein
(Clinical Chemistry and Laboratory Medicine, 2015)
C-reactive protein (CRP) is a marker of inflammation. Atherosclerosis is now recognized as inflammatory disease, and it seems that CRP directly contributes to atherogenesis. Oxidation of low-density lipoprotein (LDL) ...
Modulators of Acetylcholinesterase Activity: From Alzheimers Disease to Anti-Cancer Drugs
(Current Medicinal Chemistry, 2017)
Background: Acetylcholinesterase (AChE) is involved in the termination of impulse transmission by rapid hydrolysis of the neurotransmitter acetylcholine in numerous cholinergic pathways in the central and peripheral nervous ...
Fructose-rich diet and insulin action in female rat heart: Estradiol friend or foe?
(European Journal of Pharmacology, 2017)
Increased intake of fructose in humans and laboratory animals is demonstrated to be a risk factor for development of metabolic disorders (insulin resistance, metabolic syndrome, type 2 diabetes) and cardiovascular diseases. ...
Methylation-specific PCR: four steps in primer design
(Central European Journal of Biology, 2014)
Methylation-specific PCR (MSP) is still the method of choice for a single gene methylation study. The proper design of the primer pairs is a prerequisite for obtaining reliable PCR results. Despite numerous protocols ...
The influence of steel surface modification by electrodeposited Zn-Fe alloys on the protective behaviour of an epoxy coating
(Progress in Organic Coatings, 2003)
The electrochemical and transport properties of epoxy coatings electrodeposited on steel and steel modified by Zn-Fe alloys were investigated during exposure to 3% NaCl. The Zn-Fe alloys were deposited on steel surface ...
MicroRNA in breast cancer: The association with BRCA1/2
(Cancer Biomarkers, 2017)
Breast cancer (BC) is a heterogeneous disease in an urgent need for developing novel research, classification, and therapy approaches. Breast cancer 1 (BRCA1) and breast cancer 2 (BRCA2) proteins are well described tumor ...
miR-21 Might be Involved in Breast Cancer Promotion and Invasion Rather than in Initial Events of Breast Cancer Development
(Molecular Diagnosis and Therapy, 2016)
Breast cancer (BC) is a heterogeneous disease that develops into a large number of varied phenotypes. One of the features used in its classification and therapy selection is invasiveness. MicroRNA-21 (miR-21) is considered ...
Biochemical Markers of Renal Function
(Current Medicinal Chemistry, 2016)
Kidney damage can be induced by ischemia, autoimmune diseases, hypertension, allograft rejection, metabolic or genetic disorders, infections or toxins. The influence of these factors could result in acute kidney injury ...
HIV-1 gp120 and immune network
(International Reviews of Immunology, 2004)
It has been demonstrated that the immunodominant V3 loop of HIV-1 gp120 and its flanking regions bear sequence and structural homology to the framework and complementarity-determining regions of human immunoglobulins. It ...
Application of VIP/NTM-reactive natural antibodies in therapy of HIV disease
(International Reviews of Immunology, 2004)
In sera of HIV-infected individuals natural antibodies recognizing nonimmunogenic C-terminal domain of the second conserved region of HIV-1 gp120 and the vasoactive intestinal peptide (VIP) were identified. It has been ...